LOCUS AJ628420 1846 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens partial mRNA for type II hair keratin 4 (KRTHB4 gene).
ACCESSION AJ628420
VERSION AJ628420.1
KEYWORDS KRTHB4 gene; type II hair keratin 4.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1846)
AUTHORS Rogers M.A.
JOURNAL Submitted (20-FEB-2004) to the INSDC. Rogers M.A., Research Program
A145, German Cancer Research Center, Im Neuenheimer Feld 280,
Baden-Wurttemberg, 69120, GERMANY.
REFERENCE 3
AUTHORS Rogers M.A., Winter H., Langbein L., Wolf C., Schweizer J.
TITLE Characterization of a 300 kbp region of human DNA containing the
type II hair keratin gene domain
JOURNAL J. Invest. Dermatol. 114(3), 464-472(2000).
PUBMED 10692104
REFERENCE 4
AUTHORS Rogers M.A., Edler L., Winter H., Langbein L., Beckmann I.,
Schweizer J.
TITLE Characterization of new members of the human type II keratin gene
family and a general evaluation of the keratin gene domain on
chromosome 12q13.13
JOURNAL J. Invest. Dermatol. 124(3), 536-544(2005).
PUBMED 15737194
FEATURES Location/Qualifiers
source 1..1846
/db_xref="H-InvDB:HIT000249323"
/organism="Homo sapiens"
/chromosome="12"
/map="12q13.13"
/mol_type="mRNA"
/clone="type II hair keratin 4cdna"
/tissue_type="human scalp"
/db_xref="taxon:9606"
CDS <1..1797
/codon_start=1
/gene="KRTHB4"
/product="type II hair keratin 4"
/function="structural protein"
/db_xref="GOA:Q9NSB2"
/db_xref="H-InvDB:HIT000249323.12"
/db_xref="HGNC:HGNC:6461"
/db_xref="InterPro:IPR003054"
/db_xref="InterPro:IPR018039"
/db_xref="InterPro:IPR032444"
/db_xref="InterPro:IPR039008"
/db_xref="InterPro:IPR042180"
/db_xref="UniProtKB/Swiss-Prot:Q9NSB2"
/protein_id="CAF31524.1"
/translation="CRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRG
LGSFGSRSVITFGSYSPRIAAVGSRPVHCGVRFGAGCGMGFGDGRGVGLGPRADSCVG
LGFGAGSGIGYGFGGPGFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVK
KDEKEQIKTLNNKFTSFIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITN
LRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAF
MNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAE
VKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAE
IEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELM
NAKLGLDIEIATYRRLLEGEESRLCEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRG
GVTFSGSSSVCATSGVLASCGPSLGGARVAPATGDLLGTGTRSGSMLISEACVPSVPC
PLPTQGGFSSCSGGRSSSVRFVSTTTSCRTKY"
BASE COUNT 394 a 507 c 583 g 362 t
ORIGIN
1 tgccgctcct accgagtcag ctctggtcac cgggtgggca acttcagctc ttgttcagca
61 atgacaccac agaacctgaa tcgcttccgg gccaactctg tctcctgttg gagtgggcct
121 ggattccggg gccttggcag ctttggtagt cggagtgtca tcacctttgg atcgtactca
181 ccccggatag cagctgtagg ctctcggccc gtccactgtg gagtccgctt tggtgctggc
241 tgtgggatgg gttttggtga tgggagaggt gttggtctgg ggcctagggc tgacagctgt
301 gttggtctgg gctttggagc tggcagtggc attggctatg gctttggtgg ccctggcttt
361 ggttacagag ttggaggggt tggagtccca gcagccccat ctatcacagc tgtgactgtg
421 aacaagagcc tactgacccc cctcaacctg gagattgacc ccaatgccca gagggtgaag
481 aaggatgaga aggagcaaat caagaccctc aacaacaagt ttacctcctt cattgacaag
541 gttcggttcc tagagcagca gaataagctc ctagagacca agtggagctt cctccaagag
601 cagaaatgta tcaggagcaa tctggagcca ctcttcgaga gctacatcac caacctgcgg
661 aggcagttgg aggtgctggt cagtgatcag gcccggctcc aggctgagag gaaccacctg
721 caggatgtcc tagagggctt caagaagaag tatgaagagg aagtggtatg tcgggccaat
781 gctgagaatg agtttgtggc tctgaagaag gatgtggatg cagctttcat gaacaagtct
841 gatctcgagg ccaacgtgga taccctaact caggaaattg actttctaaa aacgctttac
901 atggaggaaa tccagttgct gcagtcgcac atctcagaga cgtcggtcat tgtgaagatg
961 gacaacagcc gtgacctgaa ccttgatggg atcattgctg aggtcaaggc ccagtatgag
1021 gaggtggcca ggcgcagccg ggctgatgct gaggcctggt accagaccaa gtatgaagag
1081 atgcaggtga cagctggcca acactgtgac aacctgcgca acatacggaa cgagatcaac
1141 gaactgaccc gcctgatcca gaggcttaag gcagagattg agcacgccaa ggctcagcgt
1201 gccaagttgg aggctgcagt ggccgaggcc gagcagcagg gcgaggcgac cctcagtgat
1261 gccaaatgca agctggcaga tctggagtgt gccctgcagc aggccaagca ggacatggcg
1321 cggcagctgt gcgagtacca ggagctgatg aatgccaagc tgggcctgga catcgagatc
1381 gccacctaca ggcgcctgct ggagggcgag gagagccggc tctgtgaagg tgttggacca
1441 gtaaacatat ccgtcagcag ctcccggggc ggcctggtgt gcgggcctga gcctttggtt
1501 gccggctcca ccctctcccg cggcggggtc accttctcag gtagcagcag cgtctgtgcc
1561 accagtgggg tcctggcttc ctgtggcccc agcctgggtg gagcccgggt cgccccggcc
1621 actggggacc tgctgggcac tggcacaagg agtggctcca tgctcatcag cgaggcctgt
1681 gtccccagcg tcccctgccc cctgcccacc caggggggct tcagcagctg cagcggcggc
1741 cgcagctcca gcgtccgctt tgtgtccacc accacctcct gccggaccaa gtactgagag
1801 cccagcccca gacagctgct gcccagagaa gaaccagctc cacggc
//