LOCUS AJ567756 1249 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens partial mRNA for KI67 Antigen (MKI67 gene), variant
lacking exons 3,4 and 7.
ACCESSION AJ567756
VERSION AJ567756.1
KEYWORDS alternative splicing; KI67 Antigen; MKI67 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1249)
AUTHORS Schmidt M.H.
JOURNAL Submitted (19-JUN-2003) to the INSDC. Schmidt M.H., Institute for
Biochemistry II, Goethe University Medical School,
Theodor-Stern-Kai 7, 60590 Frankfurt am Main, GERMANY.
REFERENCE 2
AUTHORS Schmidt M.H.H., Broll R., Bruch H.P., Finniss S., Bogler O.,
Duchrow M.
TITLE Proliferation marker pKi-67 occurs in different isoforms with
various cellular effects
JOURNAL J. Cell. Biochem. 91(6), 1280-1292(2004).
PUBMED 15048881
COMMENT Related entries: AJ567755, AJ567757
FEATURES Location/Qualifiers
source 1..1249
/db_xref="H-InvDB:HIT000248875"
/organism="Homo sapiens"
/chromosome="10"
/map="10q25-ter"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS <1..>1249
/codon_start=1
/gene="MKI67"
/product="KI67 Antigen"
/function="cell cycle regulator"
/note="variant lacking exons 3,4 and 7"
/db_xref="H-InvDB:HIT000248875.12"
/db_xref="InterPro:IPR029334"
/db_xref="UniProtKB/TrEMBL:Q70L73"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAD99006.1"
/translation="MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRYENESLQNGRKST
EFPRKIREQEPARRVSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDENLPPNTPL
KRGEAPTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSP
RKTPVASDQRRRSCKTAPASSSKSQTEVPKRGGERVATCLQKRVSISRSQHDILQMIC
SKRRSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGE
VHSQFSTGHANSPCTIIIGKAHTEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMF
KTPVKEQPQLTSTCHIAISNSENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAA
KQPSDKCSASPPLRRQCIRENGNV"
BASE COUNT 417 a 283 c 280 g 269 t
ORIGIN
1 atgtggccca cgagacgcct ggttactatc aaaaggagcg gggtcgacgg tccccacttt
61 cccctgagcc tcagcacctg cttgtttgga aggtatgaaa atgaaagtct tcagaatgga
121 aggaagtcaa ctgaatttcc aagaaaaata cgtgaacagg agccagcacg tcgtgtctca
181 agatctagct tctcttctga ccctgatgag agtgagggaa tacctttgaa aagaaggcgt
241 gtgtcctttg gtgggcacct aagacctgaa ctatttgatg aaaacttgcc tcctaatacg
301 cctctcaaaa ggggagaagc cccaaccaaa agaaagtctc tggtaatgca cactccacct
361 gtcctgaaga aaatcatcaa ggaacagcct caaccatcag gaaaacaaga gtcaggttca
421 gaaatccatg tggaagtgaa ggcacaaagc ttggttataa gccctccagc tcctagtcct
481 aggaaaactc cagttgccag tgatcaacgc cgtaggtcct gcaaaacagc ccctgcttcc
541 agcagcaaat ctcagacaga ggttcctaag agaggaggag aaagagtggc aacctgcctt
601 caaaagagag tgtctatcag ccgaagtcaa catgatattt tacagatgat atgttccaaa
661 agaagaagtg gtgcttcgga agcaaatctg attgttgcaa aatcatgggc agatgtagta
721 aaacttggtg caaaacaaac acaaactaaa gtcataaaac atggtcctca aaggtcaatg
781 aacaaaaggc aaagaagacc tgctactcca aagaagcctg tgggcgaagt tcacagtcaa
841 tttagtacag gccacgcaaa ctctccttgt accataataa tagggaaagc tcatactgaa
901 aaagtacatg tgcctgctcg accctacaga gtgctcaaca acttcatttc caaccaaaaa
961 atggacttta aggaagatct ttcaggaata gctgaaatgt tcaagacccc agtgaaggag
1021 caaccgcagt tgacaagcac atgtcacatc gctatttcaa attcagagaa tttgcttgga
1081 aaacagtttc aaggaactga ttcaggagaa gaacctctgc tccccacctc agagagtttt
1141 ggaggaaatg tgttcttcag tgcacagaat gcagcaaaac agccatctga taaatgctct
1201 gcaagccctc ccttaagacg gcagtgtatt agagaaaatg gaaacgtag
//