LOCUS AJ011001 3845 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for TM7XN1 protein.
ACCESSION AJ011001
VERSION AJ011001.1
KEYWORDS EGF-TM7-like protein; TM7XN1 protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3845)
AUTHORS Zendman A.J.W.
JOURNAL Submitted (14-SEP-1998) to the INSDC. Zendman A.J.W., Pathology,
Academical Hospital Nijmegen, Geert Grooteplein Zuid 24, P.O.Box
9101 6500 HB, THE NETHERLANDS.
REFERENCE 2
AUTHORS Zendman A.J.W., Cornelissen I.M.H.A., Weidle U.H., Ruiter D.J.,
Van Muijen G.N.P.
TITLE TM7XN1, a novel human EGF-TM7-like cDNA, detected with mRNA
differential display using human melanoma cell lines with different
metastatic potential
JOURNAL FEBS Lett. 446(2-3), 292-298(1999).
PUBMED 10100861
FEATURES Location/Qualifiers
source 1..3845
/db_xref="H-InvDB:HIT000244489"
/organism="Homo sapiens"
/chromosome="16"
/map="q13"
/mol_type="mRNA"
/cell_line="530"
/cell_type="melanoma"
/db_xref="taxon:9606"
5'UTR 1..316
sig_peptide 317..391
CDS 317..2380
/product="TM7XN1 protein"
/note="EGF-TM7 like protein"
/db_xref="GOA:Q9Y653"
/db_xref="H-InvDB:HIT000244489.12"
/db_xref="HGNC:HGNC:4512"
/db_xref="InterPro:IPR000203"
/db_xref="InterPro:IPR000832"
/db_xref="InterPro:IPR003910"
/db_xref="InterPro:IPR017981"
/db_xref="InterPro:IPR040679"
/db_xref="InterPro:IPR040950"
/db_xref="UniProtKB/Swiss-Prot:Q9Y653"
/protein_id="CAB37294.1"
/translation="MTPQSLLQTTLFLLSLLFLVQGAHGRGHREDFRFCSQRNQTHRS
SLHYKPTPDLRISIENSEEALTVHAPFPAAHPASRSFPDPRGLYHFCLYWNRHAGRLH
LLYGKRDFLLSDKASSLLCFQHQEESLAQGPPLLATSVTSWWSPQNISLPSAASFTFS
FHSPPHTAAHNASVDMCELKRDLQLLSQFLKHPQKASRRPSAAPASQQLQSLESKLTS
VRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEIMEYSVLLPRTLFQR
TKGRRGEAEKRLLLVDFSSQALFQDKNSSHVLGEKVLGIVVQNTKVANLTEPVVLTFQ
HQLQPKNVTLQCVFWVEDPTLSSPGHWSSAGCETVRRETQTSCFCNHLTYFAVLMVSS
VEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRRKPRDYTIKVHMNLLLAVFLL
DTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEGYNLYRLVVEVFGTYVPG
YLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEGVIYPSMCWIRDSLVSYI
TNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLTLLGLSLVLGLPWALIFFSF
ASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQARGGPSPLKSNSDSARLPISSGST
SSSRI"
mat_peptide 392..2377
/product="TM7XN1 protein"
protein_bind 1949..1972
/bound_moiety="tyrosine kinase"
/note="putative"
misc_binding 2339..2371
/bound_moiety="AMP"
/note="putative"
regulatory 3793..3798
/regulatory_class="polyA_signal_sequence"
polyA_site 3811
BASE COUNT 752 a 1250 c 1017 g 826 t
ORIGIN
1 gggtaccggg ccccccctcg actctagcat gcgcacagcg ggcgcagcaa cacgctggca
61 ggttaagcct ctgggggtgg atcctgaaag gtggtccagc cgcctggccc tgcgtgggac
121 cctccacctg gcagcaggta cccaaacaag ggctggacag cagggtctcg ctctgtcaca
181 caggctggag tgcagtggtg tgatcttggc tcatcgtaac ctccacctcc cgggttcaag
241 tgattctcat gcctcagcct cccgagtagc tgggattaca ggtggtgact tccaagagtg
301 actccgtcgg aggaaaatga ctccccagtc gctgctgcag acgacactgt tcctgctgag
361 tctgctcttc ctggtccaag gtgcccacgg caggggccac agggaagact ttcgcttctg
421 cagccagcgg aaccagacac acaggagcag cctccactac aaacccacac cagacctgcg
481 catctccatc gagaactccg aagaggccct cacagtccat gcccctttcc ctgcagccca
541 ccctgcttcc cgatccttcc ctgaccccag gggcctctac cacttctgcc tctactggaa
601 ccgacatgct gggagattac atcttctcta tggcaagcgt gacttcttgc tgagtgacaa
661 agcctctagc ctcctctgct tccagcacca ggaggagagc ctggctcagg gccccccgct
721 gttagccact tctgtcacct cctggtggag ccctcagaac atcagcctgc ccagtgccgc
781 cagcttcacc ttctccttcc acagtcctcc ccacacggcc gctcacaatg cctcggtgga
841 catgtgcgag ctcaaaaggg acctccagct gctcagccag ttcctgaagc atccccagaa
901 ggcctcaagg aggccctcgg ctgcccccgc cagccagcag ttgcagagcc tggagtcgaa
961 actgacctct gtgagattca tgggggacat ggtgtccttc gaggaggacc ggatcaacgc
1021 cacggtgtgg aagctccagc ccacagccgg cctccaggac ctgcacatcc actcccggca
1081 ggaggaggag cagagcgaga tcatggagta ctcggtgctg ctgcctcgaa cactcttcca
1141 gaggacgaaa ggccggaggg gggaggctga gaagagactc ctcctggtgg acttcagcag
1201 ccaagccctg ttccaggaca agaattccag ccacgtcctg ggtgagaagg tcttggggat
1261 tgtggtacag aacaccaaag tagccaacct cacggagccc gtggtgctca ccttccagca
1321 ccagctacag ccgaagaatg tgactctgca atgtgtgttc tgggttgaag accccacatt
1381 gagcagcccg gggcattgga gcagtgctgg gtgtgagacc gtcaggagag aaacccaaac
1441 atcctgcttc tgcaaccact tgacctactt tgcagtgctg atggtctcct cggtggaggt
1501 ggacgccgtg cacaagcact acctgagcct cctctcctac gtgggctgtg tcgtctctgc
1561 cctggcctgc cttgtcacca ttgccgccta cctctgctcc aggaggaaac ctcgggacta
1621 caccatcaag gtgcacatga acctgctgct ggccgtcttc ctgctggaca cgagcttcct
1681 gctcagcgag ccggtggccc tgacaggctc tgaggctggc tgccgagcca gtgccatctt
1741 cctgcacttc tccctgctca cctgcctttc ctggatgggc ctcgaggggt acaacctcta
1801 ccgactcgtg gtggaggtct ttggcaccta tgtccctggc tacctactca agctgagcgc
1861 catgggctgg ggcttcccca tctttctggt gacgctggtg gccctggtgg atgtggacaa
1921 ctatggcccc atcatcttgg ctgtgcatag gactccagag ggcgtcatct acccttccat
1981 gtgctggatc cgggactccc tggtcagcta catcaccaac ctgggcctct tcagcctggt
2041 gtttctgttc aacatggcca tgctagccac catggtggtg cagatcctgc ggctgcgccc
2101 ccacacccaa aagtggtcac atgtgctgac actgctgggc ctcagcctgg tccttggcct
2161 gccctgggcc ttgatcttct tctcctttgc ttctggcacc ttccagcttg tcgtcctcta
2221 ccttttcagc atcatcacct ccttccaagg cttcctcatc ttcatctggt actggtccat
2281 gcggctgcag gcccggggtg gcccctcccc tctgaagagc aactcagaca gcgccaggct
2341 ccccatcagc tcgggcagca cctcgtccag ccgcatctag gcctccagcc cacctgccca
2401 tgtgatgaag cagagatgcg gcctcgtcgc acactgcctg tggcccccga gccaggccca
2461 gccccaggcc agtcagccgc agactttgga aagcccaacg accatggaga gatgggccgt
2521 tgccatggtg gacggactcc cgggctgggc ttttgaattg gccttgggga ctactcggct
2581 ctcactcagc tcccacggga ctcagaagtg cgccgccatg ctgcctaggg tactgtcccc
2641 acatctgtcc caacccagct ggaggcctgg tctctcctta caacccctgg gcccagccct
2701 cattgctggg ggccaggcct tggatcttga gggtctggca catccttaat cctgtgcccc
2761 tgcctgggac agaaatgtgg ctccagttgc tctgtctctc gtggtcaccc tgagggcact
2821 ctgcatcctc tgtcatttta acctcaggtg gcacccaggg cgaatggggc ccagggcaga
2881 ccttcagggc cagagccctg gcggaggaga ggccctttgc caggagcaca gcagcagctc
2941 gcctacctct gagcccaggc cccctccctc cctcagcccc ccagtcctcc ctccatcttc
3001 cctggggttc tcctcctctc ccagggcctc cttgctcctt cgttcacagc tgggggtccc
3061 cgattccaat gctgtttttt ggggagtggt ttccaggagc tgcctggtgt ctgctgtaaa
3121 tgtttgtcta ctgcacaagc ctcggcctgc ccctgagcca ggctcggtac cgatgcgtgg
3181 gctgggctag gtccctctgt ccatctgggc ctttgtatga gctgcattgc ccttgctcac
3241 cctgaccaag cacacgcctc agaggggccc tcagcctctc ctgaagccct cttgtggcaa
3301 gaactgtgga ccatgccagt cccgtctggt ttccatccca ccactccaag gactgagact
3361 gacctcctct ggtgacactg gcctagagcc tgacactctc ctaagaggtt ctctccaagc
3421 ccccaaatag ctccaggcgc cctcggccgc ccatcatggt taattctgtc caacaaacac
3481 acacgggtag attgctggcc tgttgtaggt ggtagggaca cagatgaccg acctggtcac
3541 tcctcctgcc aacattcagt ctggtatgtg aggcgtgcgt gaagcaagaa ctcctggagc
3601 tacagggaca gggagccatc attcctgcct gggaatcctg gaagacttcc tgcaggagtc
3661 agcgttcaat cttgaccttg aagatgggaa ggatgttctt tttacgtacc aattcttttg
3721 tcttttgata ttaaaaagaa gtacatgttc attgtagaga atttggaaac tgtagaagag
3781 aatcaagaag aaaaataaaa atcagctgtt gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3841 aaaaa
//