LOCUS       AJ011001                3845 bp    mRNA    linear   HUM 07-OCT-2008
DEFINITION  Homo sapiens mRNA for TM7XN1 protein.
ACCESSION   AJ011001
VERSION     AJ011001.1
KEYWORDS    EGF-TM7-like protein; TM7XN1 protein.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3845)
  AUTHORS   Zendman A.J.W.
  JOURNAL   Submitted (14-SEP-1998) to the INSDC. Zendman A.J.W., Pathology,
            Academical Hospital Nijmegen, Geert Grooteplein Zuid 24, P.O.Box
            9101 6500 HB, THE NETHERLANDS.
REFERENCE   2
  AUTHORS   Zendman A.J.W., Cornelissen I.M.H.A., Weidle U.H., Ruiter D.J.,
            Van Muijen G.N.P.
  TITLE     TM7XN1, a novel human EGF-TM7-like cDNA, detected with mRNA
            differential display using human melanoma cell lines with different
            metastatic potential
  JOURNAL   FEBS Lett. 446(2-3), 292-298(1999).
   PUBMED   10100861
FEATURES             Location/Qualifiers
     source          1..3845
                     /db_xref="H-InvDB:HIT000244489"
                     /organism="Homo sapiens"
                     /chromosome="16"
                     /map="q13"
                     /mol_type="mRNA"
                     /cell_line="530"
                     /cell_type="melanoma"
                     /db_xref="taxon:9606"
     5'UTR           1..316
     sig_peptide     317..391
     CDS             317..2380
                     /product="TM7XN1 protein"
                     /note="EGF-TM7 like protein"
                     /db_xref="GOA:Q9Y653"
                     /db_xref="H-InvDB:HIT000244489.12"
                     /db_xref="HGNC:HGNC:4512"
                     /db_xref="InterPro:IPR000203"
                     /db_xref="InterPro:IPR000832"
                     /db_xref="InterPro:IPR003910"
                     /db_xref="InterPro:IPR017981"
                     /db_xref="UniProtKB/Swiss-Prot:Q9Y653"
                     /protein_id="CAB37294.1"
                     /translation="MTPQSLLQTTLFLLSLLFLVQGAHGRGHREDFRFCSQRNQTHRS
                     SLHYKPTPDLRISIENSEEALTVHAPFPAAHPASRSFPDPRGLYHFCLYWNRHAGRLH
                     LLYGKRDFLLSDKASSLLCFQHQEESLAQGPPLLATSVTSWWSPQNISLPSAASFTFS
                     FHSPPHTAAHNASVDMCELKRDLQLLSQFLKHPQKASRRPSAAPASQQLQSLESKLTS
                     VRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEIMEYSVLLPRTLFQR
                     TKGRRGEAEKRLLLVDFSSQALFQDKNSSHVLGEKVLGIVVQNTKVANLTEPVVLTFQ
                     HQLQPKNVTLQCVFWVEDPTLSSPGHWSSAGCETVRRETQTSCFCNHLTYFAVLMVSS
                     VEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRRKPRDYTIKVHMNLLLAVFLL
                     DTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEGYNLYRLVVEVFGTYVPG
                     YLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEGVIYPSMCWIRDSLVSYI
                     TNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLTLLGLSLVLGLPWALIFFSF
                     ASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQARGGPSPLKSNSDSARLPISSGST
                     SSSRI"
     mat_peptide     392..2377
                     /product="TM7XN1 protein"
     protein_bind    1949..1972
                     /bound_moiety="tyrosine kinase"
                     /note="putative"
     misc_binding    2339..2371
                     /bound_moiety="AMP"
                     /note="putative"
     regulatory      3793..3798
                     /regulatory_class="polyA_signal_sequence"
     polyA_site      3811
BASE COUNT          752 a         1250 c         1017 g          826 t
ORIGIN      
        1 gggtaccggg ccccccctcg actctagcat gcgcacagcg ggcgcagcaa cacgctggca
       61 ggttaagcct ctgggggtgg atcctgaaag gtggtccagc cgcctggccc tgcgtgggac
      121 cctccacctg gcagcaggta cccaaacaag ggctggacag cagggtctcg ctctgtcaca
      181 caggctggag tgcagtggtg tgatcttggc tcatcgtaac ctccacctcc cgggttcaag
      241 tgattctcat gcctcagcct cccgagtagc tgggattaca ggtggtgact tccaagagtg
      301 actccgtcgg aggaaaatga ctccccagtc gctgctgcag acgacactgt tcctgctgag
      361 tctgctcttc ctggtccaag gtgcccacgg caggggccac agggaagact ttcgcttctg
      421 cagccagcgg aaccagacac acaggagcag cctccactac aaacccacac cagacctgcg
      481 catctccatc gagaactccg aagaggccct cacagtccat gcccctttcc ctgcagccca
      541 ccctgcttcc cgatccttcc ctgaccccag gggcctctac cacttctgcc tctactggaa
      601 ccgacatgct gggagattac atcttctcta tggcaagcgt gacttcttgc tgagtgacaa
      661 agcctctagc ctcctctgct tccagcacca ggaggagagc ctggctcagg gccccccgct
      721 gttagccact tctgtcacct cctggtggag ccctcagaac atcagcctgc ccagtgccgc
      781 cagcttcacc ttctccttcc acagtcctcc ccacacggcc gctcacaatg cctcggtgga
      841 catgtgcgag ctcaaaaggg acctccagct gctcagccag ttcctgaagc atccccagaa
      901 ggcctcaagg aggccctcgg ctgcccccgc cagccagcag ttgcagagcc tggagtcgaa
      961 actgacctct gtgagattca tgggggacat ggtgtccttc gaggaggacc ggatcaacgc
     1021 cacggtgtgg aagctccagc ccacagccgg cctccaggac ctgcacatcc actcccggca
     1081 ggaggaggag cagagcgaga tcatggagta ctcggtgctg ctgcctcgaa cactcttcca
     1141 gaggacgaaa ggccggaggg gggaggctga gaagagactc ctcctggtgg acttcagcag
     1201 ccaagccctg ttccaggaca agaattccag ccacgtcctg ggtgagaagg tcttggggat
     1261 tgtggtacag aacaccaaag tagccaacct cacggagccc gtggtgctca ccttccagca
     1321 ccagctacag ccgaagaatg tgactctgca atgtgtgttc tgggttgaag accccacatt
     1381 gagcagcccg gggcattgga gcagtgctgg gtgtgagacc gtcaggagag aaacccaaac
     1441 atcctgcttc tgcaaccact tgacctactt tgcagtgctg atggtctcct cggtggaggt
     1501 ggacgccgtg cacaagcact acctgagcct cctctcctac gtgggctgtg tcgtctctgc
     1561 cctggcctgc cttgtcacca ttgccgccta cctctgctcc aggaggaaac ctcgggacta
     1621 caccatcaag gtgcacatga acctgctgct ggccgtcttc ctgctggaca cgagcttcct
     1681 gctcagcgag ccggtggccc tgacaggctc tgaggctggc tgccgagcca gtgccatctt
     1741 cctgcacttc tccctgctca cctgcctttc ctggatgggc ctcgaggggt acaacctcta
     1801 ccgactcgtg gtggaggtct ttggcaccta tgtccctggc tacctactca agctgagcgc
     1861 catgggctgg ggcttcccca tctttctggt gacgctggtg gccctggtgg atgtggacaa
     1921 ctatggcccc atcatcttgg ctgtgcatag gactccagag ggcgtcatct acccttccat
     1981 gtgctggatc cgggactccc tggtcagcta catcaccaac ctgggcctct tcagcctggt
     2041 gtttctgttc aacatggcca tgctagccac catggtggtg cagatcctgc ggctgcgccc
     2101 ccacacccaa aagtggtcac atgtgctgac actgctgggc ctcagcctgg tccttggcct
     2161 gccctgggcc ttgatcttct tctcctttgc ttctggcacc ttccagcttg tcgtcctcta
     2221 ccttttcagc atcatcacct ccttccaagg cttcctcatc ttcatctggt actggtccat
     2281 gcggctgcag gcccggggtg gcccctcccc tctgaagagc aactcagaca gcgccaggct
     2341 ccccatcagc tcgggcagca cctcgtccag ccgcatctag gcctccagcc cacctgccca
     2401 tgtgatgaag cagagatgcg gcctcgtcgc acactgcctg tggcccccga gccaggccca
     2461 gccccaggcc agtcagccgc agactttgga aagcccaacg accatggaga gatgggccgt
     2521 tgccatggtg gacggactcc cgggctgggc ttttgaattg gccttgggga ctactcggct
     2581 ctcactcagc tcccacggga ctcagaagtg cgccgccatg ctgcctaggg tactgtcccc
     2641 acatctgtcc caacccagct ggaggcctgg tctctcctta caacccctgg gcccagccct
     2701 cattgctggg ggccaggcct tggatcttga gggtctggca catccttaat cctgtgcccc
     2761 tgcctgggac agaaatgtgg ctccagttgc tctgtctctc gtggtcaccc tgagggcact
     2821 ctgcatcctc tgtcatttta acctcaggtg gcacccaggg cgaatggggc ccagggcaga
     2881 ccttcagggc cagagccctg gcggaggaga ggccctttgc caggagcaca gcagcagctc
     2941 gcctacctct gagcccaggc cccctccctc cctcagcccc ccagtcctcc ctccatcttc
     3001 cctggggttc tcctcctctc ccagggcctc cttgctcctt cgttcacagc tgggggtccc
     3061 cgattccaat gctgtttttt ggggagtggt ttccaggagc tgcctggtgt ctgctgtaaa
     3121 tgtttgtcta ctgcacaagc ctcggcctgc ccctgagcca ggctcggtac cgatgcgtgg
     3181 gctgggctag gtccctctgt ccatctgggc ctttgtatga gctgcattgc ccttgctcac
     3241 cctgaccaag cacacgcctc agaggggccc tcagcctctc ctgaagccct cttgtggcaa
     3301 gaactgtgga ccatgccagt cccgtctggt ttccatccca ccactccaag gactgagact
     3361 gacctcctct ggtgacactg gcctagagcc tgacactctc ctaagaggtt ctctccaagc
     3421 ccccaaatag ctccaggcgc cctcggccgc ccatcatggt taattctgtc caacaaacac
     3481 acacgggtag attgctggcc tgttgtaggt ggtagggaca cagatgaccg acctggtcac
     3541 tcctcctgcc aacattcagt ctggtatgtg aggcgtgcgt gaagcaagaa ctcctggagc
     3601 tacagggaca gggagccatc attcctgcct gggaatcctg gaagacttcc tgcaggagtc
     3661 agcgttcaat cttgaccttg aagatgggaa ggatgttctt tttacgtacc aattcttttg
     3721 tcttttgata ttaaaaagaa gtacatgttc attgtagaga atttggaaac tgtagaagag
     3781 aatcaagaag aaaaataaaa atcagctgtt gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     3841 aaaaa
//