LOCUS AF313907 1845 bp mRNA linear HUM 01-FEB-2001
DEFINITION Homo sapiens 3'-phosphoadenosine 5'-phosphosulfate synthase 2 alpha
mRNA, complete cds.
ACCESSION AF313907
VERSION AF313907.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1845)
AUTHORS Fuda,H., Shimizu,C. and Strott,C.A.
TITLE Human Bifunctional 3'-Phosphoadenosine 5'-Phosphosulfate Synthase:
Differential Expression of Isoforms and Effect of Polymorphisms on
Activity
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1845)
AUTHORS Shimizu,C., Fuda,H. and Strott,C.A.
TITLE Direct Submission
JOURNAL Submitted (17-OCT-2000) Section on Steroid Regulation, NICHD/NIH,
9000 Rockville Pike, Bethesda, MD 20892-4510, USA
FEATURES Location/Qualifiers
source 1..1845
/db_xref="H-InvDB:HIT000077089"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 1..1845
/function="catalyzes production of 3'-phosphoadenosine
5'-phosphosulfate, the universal sulfonate donor molecule,
from inorganic sulfate and ATP"
/codon_start=1
/product="3'-phosphoadenosine 5'-phosphosulfate synthase 2
alpha"
/protein_id="AAK00296.1"
/translation="MSGIKKQKTENQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCT
VWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNRNLGFSPGDREENIRR
IAEVAKLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDV
KGLYKRARAGEIKGFTGIDSDYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVPY
TIIKDIHELFVPENKLDHVRAEAETLPSLSITKLDLQWVQVLSEGWATPLKGFMREKE
YLQVMHFDTLLDDGVINMSIPIVLPVSAEDKTRLEGCSKFVLAHGGRRVAILRDAEFY
EHRKEERCSRVWGTTCTKHPHIKMVMGSGDWLVGGDLQVLEKIRWNDGLDQYRLTPLE
LKQKCKEMNADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKD
DDVPLDWRMKQHAAVLEEGVLDPKSTIVAIFPSPMLYAGPTEVQWHCRSRMIAGANFY
IVGRDPAGMPHPETKKDLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKAKKAMDFYD
PARHNEFDFISGTRMRKLAREGENPPDGFMAPKAWKVLTDYYRSLEKN"
BASE COUNT 494 a 436 c 496 g 419 t
ORIGIN
1 atgtcgggga tcaagaagca aaagacggag aaccagcaga aatccaccaa tgtagtctat
61 caggcccacc atgtgagcag gaataagaga gggcaagtgg ttggaacaag gggtgggttc
121 cgaggatgta ccgtgtggct aacaggtctc tctggtgctg gaaaaacaac gataagtttt
181 gccctggagg agtaccttgt ctcccatgcc atcccttgtt actccctgga tggggacaat
241 gtccgtcatg gccttaacag aaatctcgga ttctctcctg gggacagaga ggaaaatatc
301 cgccggattg ctgaggtggc taagctgttt gctgatgctg gtctggtctg cattaccagc
361 tttatttctc cattcgcaaa ggatcgtgag aatgcccgca aaatacatga atcagcaggg
421 ctgccattct ttgaaatatt tgtagatgca cctctaaata tttgtgaaag cagagacgta
481 aaaggcctct ataaaagggc cagagctggg gagattaaag gatttacagg tattgattct
541 gattatgaga aacctgaaac tcctgagcgt gtgcttaaaa ccaatttgtc cacagtgagt
601 gactgtgtcc accaggtagt ggaacttctg caagagcaga acattgtacc ctatactata
661 atcaaagata tccacgaact ctttgtgccg gaaaacaaac ttgaccacgt ccgagctgag
721 gctgaaactc tcccttcatt atcaattact aagctggatc tccagtgggt ccaggttttg
781 agcgaaggct gggccactcc cctcaaaggt ttcatgcggg agaaggagta cttacaggtt
841 atgcactttg acaccctgct agatgatggc gtgatcaaca tgagcatccc cattgtactg
901 cccgtctctg cagaggataa gacacggctg gaagggtgca gcaagtttgt cctggcacat
961 ggtggacgga gggtagctat cttacgagac gctgaattct atgaacacag aaaagaggaa
1021 cgctgttccc gtgtttgggg gacaacatgt acaaaacacc cccatatcaa aatggtgatg
1081 ggaagtgggg actggctggt tggtggagac cttcaggtgc tggagaaaat aagatggaat
1141 gatgggctgg accaataccg tctgacacct ctggagctca aacagaaatg taaagaaatg
1201 aatgctgatg cggtgtttgc attccagttg cgcaatcctg tccacaatgg ccatgccctg
1261 ttgatgcagg acactcgccg caggctccta gagaggggct acaagcaccc ggtcctccta
1321 ctacaccctc tgggcggctg gaccaaggat gacgatgtgc ctctagactg gcggatgaag
1381 cagcacgcgg ctgtgctcga ggaaggggtc ctggatccca agtcaaccat tgttgccatc
1441 tttccgtctc ccatgttata tgctggcccc acagaggtcc agtggcactg caggtcccgg
1501 atgattgcgg gtgccaattt ctacattgtg gggagggacc ctgcaggaat gccccatcct
1561 gaaaccaaga aggatctgta tgaacccact catgggggca aggtcttgag catggcccct
1621 ggcctcacct ctgtggaaat cattccattc cgagtggctg cctacaacaa agccaaaaaa
1681 gccatggact tctatgatcc agcaaggcac aatgagtttg acttcatctc aggaactcga
1741 atgaggaagc tcgcccggga aggagagaat cccccagatg gcttcatggc ccccaaagca
1801 tggaaggtcc tgacagatta ttacaggtcc ctggagaaga actaa
//