LOCUS AF288991 1519 bp mRNA linear HUM 12-NOV-2000
DEFINITION Homo sapiens 15 kDa selenoprotein (SEP15) mRNA, complete cds;
alternatively spliced.
ACCESSION AF288991
VERSION AF288991.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1519)
AUTHORS Kumaraswamy,E., Malykh,A., Korotkov,K.V., Kozyavkin,S., Hu,Y.,
Kwon,S.Y., Moustafa,M.E., Carlson,B.A., Berry,M.J., Lee,B.J.,
Hatfield,D.L., Diamond,A.M. and Gladyshev,V.N.
TITLE Structure-expression relationships of the 15-kDa selenoprotein
gene. Possible role of the protein in cancer etiology
JOURNAL J. Biol. Chem. 275 (45), 35540-35547 (2000)
PUBMED 10945981
REFERENCE 2 (bases 1 to 1519)
AUTHORS Kumaraswamy,E., Malykh,A., Korotkov,K.V., Kozyavkin,S., Hu,Y.,
Kwon,S., Moustafa,M.E., Carlson,B.A., Berry,M.J., Lee,B.J.,
Hatfield,D.L., Diamond,A.M. and Gladyshev,V.N.
TITLE Direct Submission
JOURNAL Submitted (21-JUL-2000) Department of Biochemistry, University of
Nebraska, N151 Beadle Center, Lincoln, NE 68588, USA
FEATURES Location/Qualifiers
source 1..1519
/db_xref="H-InvDB:HIT000076369"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31"
gene 1..1519
/gene="SEP15"
CDS 5..493
/gene="SEP15"
/note="alternatively spliced; long alternative transcript;
contains SECIS element"
/codon_start=1
/transl_except=(pos:281..283,aa:Sec)
/product="15 kDa selenoprotein"
/protein_id="AAG31556.1"
/translation="MAAGPSGCLVPAFGLRLLLATVLQAVSAFGAEFSSEACRELGFS
SNLLCSSCDLLGQFNLLQLDPDCRGCCQEEAQFETKKLYAGAILEVCGUKLGRFPQVQ
AFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLE
RI"
BASE COUNT 458 a 245 c 292 g 524 t
ORIGIN
1 agcgatggcg gctgggccga gtgggtgtct ggtgccggcg tttgggctac ggttgttgtt
61 ggcgactgtg cttcaagcgg tgtctgcttt tggggcagag ttttcatcgg aggcatgcag
121 agagttaggc ttttctagca acttgctttg cagctcttgt gatcttctcg gacagttcaa
181 cctgcttcag ctggatcctg attgcagagg atgctgtcag gaggaagcac aatttgaaac
241 caaaaagctg tatgcaggag ctattcttga agtttgtgga tgaaaattgg gaaggttccc
301 tcaagtccaa gcttttgtta ggagtgataa acccaaactg ttcagaggac tgcaaatcaa
361 gtatgtccgt ggttcagacc ctgtattaaa gcttttggac gacaatggga acattgctga
421 agaactgagc attctcaaat ggaacacaga cagtgtagaa gaattcctga gtgaaaagtt
481 ggaacgcata taaatcttgc ttaaattttg tcctatcctt ttgttacctt atcaaatgaa
541 atattacagc acctagaaaa taatttagtt ttgcttgctt ccattgatca gtcttttact
601 tgaggcatta aatatctaat taaatcgtga aatggcagta tagtccatga tatctaagga
661 gttggcaagc ttaacaaaac ccatttttta taaatgtcca tcctcctgca tttgttgata
721 ccactaacaa aatgctttgt aacagacttg cggttaatta tgcaaatgat agtttgtgat
781 aattggtcca gttttacgaa caacagattt ctaaattaga gaggttaaca agacagatga
841 ttactatgcc tcatgtgctg tgtgctcttt gaaaggaatg acagcagact acaaagcaaa
901 taagatatac tgagcctcaa cagattgcct gctcctcaga gtctctccta tttttgtatt
961 acccagcttt ctttttaata caaatgttat ttatagttta caatgaatgc actgcataaa
1021 aactttgtag cttcattatt gtaaaacata ttcaagatcc tacagtaaga gtgaaacatt
1081 cacaaagatt tgcgttaatg aagactacac agaaaacctt tctagggatt tgtgtggatc
1141 agatacatac ttggcaaatt tttgagtttt acattcttac agaaaagtcc atttaaaagt
1201 gatcatttgt aagaccaaaa tataaataaa aagtttcaaa aatctatctg aatttggaat
1261 tcttctggtt tgttctttca tgtttaaaaa tgatgttttt caatgcattt ttttcatgta
1321 agcccttttt ttagccaaaa tgtaaaaatg gctgtaatat ttaaaactta taacatctta
1381 ttgttggtaa tagtgcttta tatttgtctg attttatttt tcaaagtttt ttcatttatg
1441 aacacatttt cattggtata ttatttaagg aatatctctt gatatagaat ttttatatta
1501 aaaatgattt ttctttggc
//