LOCUS AF275816 2903 bp mRNA linear HUM 23-JUL-2000
DEFINITION Homo sapiens PR-domain containing protein 9 (PRDM9) mRNA, complete
cds.
ACCESSION AF275816
VERSION AF275816.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2903)
AUTHORS Yang,X.-h. and Huang,S.
TITLE A family of novel PR-domain (PRDM) genes as candidate tumor
suppressors
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2903)
AUTHORS Yang,X.-h. and Huang,S.
TITLE Direct Submission
JOURNAL Submitted (08-JUN-2000) Oncogenes and Tumor Suppressor Genes, The
Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA
92037, USA
FEATURES Location/Qualifiers
source 1..2903
/db_xref="H-InvDB:HIT000075947"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5p14"
gene 1..2903
/gene="PRDM9"
CDS 10..2079
/gene="PRDM9"
/note="PFM6; contains zinc fingers; PR-domain family
member 6"
/codon_start=1
/product="PR-domain containing protein 9"
/protein_id="AAF87242.1"
/translation="MCQNFFIDSCAAHGPPTFVKDSAVDKGHPNRSALSLPPGLRIGP
SGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANNGYSWLVRRACHFTKGRNCY
EYVDGKDKSWANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVWYGDE
YGQELGIKWGSKWKKEEPKPEIHPCPSCCLAFSSQKFLSQHVERNHSSQNFPGPSARK
LLQPENPCPGDQNQEQQYPDPHSRNDKTKGQEIKERSKLLNKRTWQREISRAFSSPPK
GQMGSCRVGKRIMEEESRTGQKVNPGNTGKLFVGVGISRIAKVKYGECGQGFSVKSDV
ITHQRTHTGEKLYVCRECGRGFSWKSHLLIHQRIHTGEKPYVCRECGRGFSWQSVLLT
HQRTHTGEKPYVCRECGRGFSRQSVLLTHQRRHTGEKPYVCRECGRGFSRQSVLLTHQ
RRHTGEKPYVCRECGRGFSWQSVLLTHQRTHTGEKPYVCRECGRGFSWQSVLLTHQRT
HTGEKPYVCRECGRGFSNKSHLLRHQRTHTGEKPYVCRECGRGFRDKSHLLRHQRTHT
GEKPYVCRECGRGFRDKSNLLSHQRTHTGEKPYVCRECGRGFSNKSHLLRHQRTHTGE
KPYVCRECGRGFRNKSHLLRHQRTHTGEKPYVCRECGRGFSDRSSLCYHQRTHTGEKP
YVCREDE"
BASE COUNT 793 a 702 c 811 g 597 t
ORIGIN
1 gattgtgaga tgtgtcagaa cttcttcatt gacagctgtg ctgcccatgg gccccctaca
61 tttgtaaagg acagtgcagt ggacaagggg caccccaacc gttcagccct cagtctgccc
121 ccagggctga gaattgggcc atcaggcatc cctcaggctg ggcttggagt atggaatgag
181 gcatctgatc tgccgctggg tctgcacttt ggcccttatg agggccgaat tacagaagac
241 gaagaggcag ccaacaatgg atactcctgg ctggtaagaa gagcctgcca tttcaccaag
301 gggagaaact gctatgagta tgtggatgga aaagataaat cctgggccaa ctggatgagg
361 tatgtgaact gtgcccggga tgatgaagag cagaacctgg tggccttcca gtaccacagg
421 cagatcttct atagaacctg ccgagtcatt aggccaggct gtgaactgct ggtctggtat
481 ggggatgaat acggccagga actgggcatc aagtggggca gcaagtggaa gaaagaggaa
541 ccaaagccag agatccatcc atgtccctca tgctgtctgg ccttttcaag tcagaaattt
601 ctcagtcaac atgtagaacg caatcactcc tctcagaact tcccaggacc atctgcaaga
661 aaactcctcc aaccagagaa tccctgccca ggggatcaga atcaggagca gcaatatcca
721 gatccacaca gccgtaatga caaaaccaaa ggtcaagaga tcaaagaaag gtccaaactc
781 ttgaataaaa ggacatggca gagggagatt tcaagggcct tttctagccc acccaaagga
841 caaatgggga gctgtagagt gggaaaaaga ataatggaag aagagtccag aacaggccag
901 aaagtgaatc cagggaacac aggcaaatta tttgtggggg taggaatctc aagaattgca
961 aaagtcaagt atggagagtg tggacaaggt ttcagtgtta aatcagatgt tattacacac
1021 caaaggacac atacagggga gaagctctac gtctgcaggg agtgtgggcg gggctttagc
1081 tggaagtcac acctcctcat tcaccagagg atacacacag gggagaagcc ctatgtctgc
1141 agggagtgtg ggcggggctt tagctggcag tcagtcctcc tcactcacca gaggacacac
1201 acaggggaga agccctatgt ctgcagggag tgtgggcggg gctttagccg gcagtcagtc
1261 ctcctcactc accagaggag acacacaggg gagaagccct atgtctgcag ggagtgtggg
1321 cggggcttta gccggcagtc agtcctcctc actcaccaga ggagacacac aggggagaag
1381 ccctatgtct gcagggagtg tgggcggggc tttagctggc agtcagtcct cctcactcac
1441 cagaggacac acacagggga gaagccctat gtctgcaggg agtgtgggcg gggctttagc
1501 tggcagtcag tcctcctcac tcaccagagg acacacacag gggagaagcc ctatgtctgc
1561 agggagtgtg ggcggggctt tagcaataag tcacacctcc tcagacacca gaggacacac
1621 acaggggaga agccctatgt ctgcagggag tgtgggcggg gctttcgcga taagtcacac
1681 ctcctcagac accagaggac acacacaggg gagaagccct atgtctgcag ggagtgtggg
1741 cggggcttta gagataagtc aaacctcctc agtcaccaga ggacacacac aggggagaag
1801 ccctatgtct gcagggagtg tgggcggggc tttagcaata agtcacacct cctcagacac
1861 cagaggacac acacagggga gaagccctat gtctgcaggg agtgtgggcg gggctttcgc
1921 aataagtcac acctcctcag acaccagagg acacacacag gggagaagcc ctacgtctgc
1981 agggagtgtg ggcggggctt tagcgatagg tcaagcctct gctatcacca gaggacacac
2041 acaggggaga agccctacgt ctgcagggag gatgagtaag tcattagtaa taaaacctca
2101 tctcaatagc cacaaaaaga caaatgtggt caccacacac ttgcacaccc cagctgtgag
2161 gtggcttcag cggaagtctg ctgacccctt atattccccg agagtataaa gagatcggaa
2221 ataactgatt aaacaaatcc gccactttca tgactagaga tgaggaagaa caagggatag
2281 ttctgtaagt gttcggggga catcagcatg tgtggttctt tcccgcactg atcccctcca
2341 ttttttgttt gtttttttgc ctcctgttct aataaatttt gtctccatac aaatctgaac
2401 cccaagtgtg tacctcattc ttcccttatc actgaaggca agaagagtcc agaagggcca
2461 cagagaactc atgtgttcag ctcaagactc cacaggaatt caacccccag aaagacataa
2521 acttggagtc cgtctggttt aattattgga gaatcgattc ccaagtccag gaagagaaat
2581 gtaagattct agaaagtcgc agcaggaaag ggagttccct ggtctcctgg gaagtgtggc
2641 ttcttctcct aatggacacc tctcctctgc tgccatactc tcccttggct ccccagtctc
2701 ctctcctgat ctcctccaat ctctgtagcc caagatgtga aagccagaca agaacacgcg
2761 tgtgtgtata tatgtgttcg ggtgtggggg tatgtgccct ccgtgtaggt aactgtgtga
2821 gtgtgggggg tttcaagggt gtgttaggaa caacgctcaa aatcctaagg aaactgaaca
2881 ctcgaacgaa ggattcttag caa
//