LOCUS AF203694 1875 bp mRNA linear HUM 22-AUG-2000
DEFINITION Homo sapiens glucocorticoid modulatory element binding protein 1
(GMEB1) mRNA, complete cds.
ACCESSION AF203694
VERSION AF203694.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1875)
AUTHORS Kaul,S., Blackford,J.A. Jr., Chen,J., Ogryzko,V.V. and Simons,S.S.
Jr.
TITLE Properties of the glucocorticoid modulatory element binding
proteins GMEB-1 and -2: potential new modifiers of glucocorticoid
receptor transactivation and members of the family of KDWK proteins
JOURNAL Mol. Endocrinol. 14 (7), 1010-1027 (2000)
PUBMED 10894151
REFERENCE 2 (bases 1 to 1875)
AUTHORS Kaul,S. and Simons,S.S. Jr.
TITLE Direct Submission
JOURNAL Submitted (11-NOV-1999) Steroid Hormones Section, NIDDK/NIH, Bldg.
8, Room B2A-07, MSC 0805, Bethesda, MD 20892-0805, USA
FEATURES Location/Qualifiers
source 1..1875
/db_xref="H-InvDB:HIT000073808"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
gene 1..1875
/gene="GMEB1"
CDS 67..1758
/gene="GMEB1"
/note="binds as homo- and heterooligomer to glucocorticoid
modulatory element (GME) about 3.6 kb upstream of the rat
tyrosine aminotransferase (TAT) gene"
/codon_start=1
/product="glucocorticoid modulatory element binding
protein 1"
/protein_id="AAG01189.1"
/translation="MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGI
YEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCGESKAILLWKKFV
CPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQH
DKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLE
WNSALTAAVTMATEEGVKKDSEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRG
VQQRLIQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRRNQVEQGEEQFLYTLTDLER
QLEEQKKQGQDHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQF
TVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSP
DTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDG
QTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED"
BASE COUNT 526 a 449 c 485 g 415 t
ORIGIN
1 cgccctggcc gctcgccgcc cgcccgcccg acgaagacgt cccagctatc tgacttcatg
61 tgaaagatgg ctaatgcaga agtgagtgtc ccagtggggg atgtggttgt ggtacctact
121 gaaggaaatg aaggggagaa tcctgaagac actaaaaccc aagtgatttt gcagttacag
181 cctgtgcaac aagggattta tgaagctggg tcggagaaca acacggcagt tgtagcagta
241 gaaactcaca cgatacacaa aattgaagaa gggattgata caggcactat agaagcaaat
301 gaggatatgg aaattgctta ccccataact tgtggggaga gcaaagccat cctcctctgg
361 aagaagtttg tatgtccagg aataaacgtg aagtgtgtca agttcaatga tcagttgatc
421 agccccaagc actttgttca tctggctggc aagtccactc tgaaggactg gaagagagct
481 attcgtctgg gtgggatcat gctcaggaaa atgatggact ccggacagat tgatttttac
541 caacatgaca aagtttgctc caatacctgc agaagcacca aatttgatct tctgatcagc
601 agtgcaagag ctccagtgcc aggacagcag acaagtgtgg tgcagacacc cacttcggct
661 gatggtagca tcacgcagat tgccatctca gaagagagca tggaagaggc agggctggaa
721 tggaactcag ctctcaccgc tgctgtcacc atggccacgg aggagggtgt aaagaaagac
781 tcagaggaaa tttcagagga cactttgatg ttctggaaag gaatagctga tgtagggctg
841 atggaagagg ttgtctgcaa tatacagaag gaaatagagg agctactcag gggagttcag
901 cagcggctca tccaggctcc cttccaagtc acagatgctg ctgttctcaa caatgtagca
961 cacacatttg gcctaatgga cacagtcaag aaggttttag acaacagaag gaaccaagta
1021 gagcagggag aagaacagtt tctctatact ctgacagact tggaacgcca gttggaggag
1081 cagaagaagc aaggccagga tcacaggctg aaatctcaga cagttcaaaa tgtggtactg
1141 atgcctgtga gcactcctaa gcctccaaaa aggccccggc tccagcggcc agcctccacc
1201 actgtcttga gcccttctcc tcctgtccag cagcctcagt tcacagtcat ctcacccatc
1261 accatcaccc cagtgggtca gtcattttcc atgggcaata ttccagtggc caccctcagc
1321 cagggctcca gtcctgtgac tgtccacaca ctgccttctg gccctcagct cttccgctat
1381 gccacagtgg tctcctctgc caagagcagc tcaccagaca cagtgaccat ccacccttca
1441 tctagcttgg cgctgctgag ctctactgcc atgcaggatg ggagtacact gggcaacatg
1501 accaccatgg ttagccctgt ggaattggtg gccatggagt ccggcctaac ctcggcaatt
1561 caggctgttg aaagcacctc agaggatggg cagaccatca ttgagattga tccagccccg
1621 gacccagaag ctgaagatac tgagggcaaa gcagtcatct tggagacaga gctgaggact
1681 gaggagaaag ttgtggctga gatggaagaa caccagcatc aagttcacaa tgtggagatt
1741 gtggtcttag aggattaact ggggatctca gggccaggag ttatgttttg atttggaatt
1801 ttaaattatt tgtttatttt tatcattgtc ccactcattt ccacataggg cccctttttt
1861 aaaaaaaaaa aaaaa
//