LOCUS AF173365 1909 bp mRNA linear HUM 23-NOV-1999
DEFINITION Homo sapiens ATP sulfurylase/APS kinase isoform SK2 mRNA,
alternatively spliced, complete cds.
ACCESSION AF173365
VERSION AF173365.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1909)
AUTHORS Kurima,K., Warman,M.L., Krishnan,S., Domowicz,M., Krueger,R.C. Jr.,
Deyrup,A. and Schwartz,N.B.
TITLE A member of a family of sulfate-activating enzymes causes murine
brachymorphism
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (15), 8681-8685 (1998)
PUBMED 9671738
REFERENCE 2 (bases 1 to 1909)
AUTHORS Kurima,K., Singh,B. and Schwartz,N.B.
TITLE Genomic organization of the mouse and human genes encoding the ATP
sulfurylase/adenosine 5'-phosphosulfate kinase isoform SK2
JOURNAL J. Biol. Chem. 274 (47), 33306-33312 (1999)
PUBMED 10559207
REFERENCE 3 (bases 1 to 1909)
AUTHORS Kurima,K., Singh,B. and Schwartz,N.B.
TITLE Direct Submission
JOURNAL Submitted (28-JUL-1999) Pediatrics, University of Chicago, 5841 S.
Maryland Ave. MC5058, Chicago, IL 60637, USA
FEATURES Location/Qualifiers
source 1..1909
/db_xref="H-InvDB:HIT000072455"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/tissue_type="liver"
/dev_stage="fetus"
5'UTR 1..48
CDS 49..1908
/EC_number="2.7.7.4"
/EC_number="2.7.1.25"
/note="bifunctional enzyme; alternatively spliced"
/codon_start=1
/product="ATP sulfurylase/APS kinase isoform SK2"
/protein_id="AAF12761.1"
/translation="MSGIKKQKTENQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCT
VWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNRNLGFSPGDREENIRR
IAEVAKLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDV
KGLYKRARAGEIKGFTGIDSDYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVPY
TIIKDIHELFVPENKLDHVRAEAETLPSLSITKLDLQWVQVLSEGWATPLKGFMREKE
YLQVMHFDTLLDGMALPDGVINMSIPIVLPVSAEDKTRLEGCSKFVLAHGGRRVAILR
DAEFYEHRKEERCSRVWGTTCTKHPHIKMVMESGDWLVGGDLQVLEKIRWNDGLDQYR
LTPLELKQKCKEMNADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLG
GWTKDDDVPLDWRMKQHAAVLEEGVLDPKSTIVAIFPSPMLYAGPTEVQWHCRSRMIA
GANFYIVGRDPAGMPHPETKKDLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKAKKA
MDFYDPARHNEFDFISGTRMRKLAREGENPPDGFMAPKAWKVLTDYYRSLEKN"
BASE COUNT 500 a 465 c 514 g 430 t
ORIGIN
1 ccttcggtct ctgctcccgg gacccgggct ccgccgcagc cagccagcat gtcggggatc
61 aagaagcaaa agacggagaa ccagcagaaa tccaccaatg tagtctatca ggcccaccat
121 gtgagcagga ataagagagg gcaagtggtt ggaacaaggg gtgggttccg aggatgtacc
181 gtgtggctaa caggtctctc tggtgctgga aaaacaacga taagttttgc cctggaggag
241 taccttgtct cccatgccat cccttgttac tccctggatg gggacaatgt ccgtcatggc
301 cttaacagaa atctcggatt ctctcctggg gacagagagg aaaatatccg ccggattgct
361 gaggtggcta agctgtttgc tgatgctggt ctggtctgca ttaccagctt tatttctcca
421 ttcgcaaagg atcgtgagaa tgcccgcaaa atacatgaat cagcagggct gccattcttt
481 gaaatatttg tagatgcacc tctaaatatt tgtgaaagca gagacgtaaa aggcctctat
541 aaaagggcca gagctgggga gattaaagga tttacaggta ttgattctga ttatgagaaa
601 cctgaaactc ctgagcgtgt gcttaaaacc aatttgtcca cagtgagtga ctgtgtccac
661 caggtagtgg aacttctgca agagcagaac attgtaccct atactataat caaagatatc
721 cacgaactct ttgtgccgga aaacaaactt gaccacgtcc gagctgaggc tgaaactctc
781 ccttcattat caattactaa gctggatctc cagtgggtcc aggttttgag cgaaggctgg
841 gccactcccc tcaaaggttt catgcgggag aaggagtact tacaggttat gcactttgac
901 accctgctag atggcatggc ccttcctgat ggcgtgatca acatgagcat ccccattgta
961 ctgcccgtct ctgcagagga taagacacgg ctggaagggt gcagcaagtt tgtcctggca
1021 catggtggac ggagggtagc tatcttacga gacgctgaat tctatgaaca cagaaaagag
1081 gaacgctgtt cccgtgtttg ggggacaaca tgtacaaaac acccccatat caaaatggtg
1141 atggaaagtg gggactggct ggttggtgga gaccttcagg tgctggagaa aataagatgg
1201 aatgatgggc tggaccaata ccgtctgaca cctctggagc tcaaacagaa atgtaaagaa
1261 atgaatgctg atgcggtgtt tgcattccag ttgcgcaatc ctgtccacaa tggccatgcc
1321 ctgttgatgc aggacactcg ccgcaggctc ctagagaggg gctacaagca cccggtcctc
1381 ctactacacc ctctgggcgg ctggaccaag gatgacgatg tgcctctaga ctggcggatg
1441 aagcagcacg cggctgtgct cgaggaaggg gtcctggatc ccaagtcaac cattgttgcc
1501 atctttccgt ctcccatgtt atatgctggc cccacagagg tccagtggca ctgcaggtcc
1561 cggatgattg cgggtgccaa tttctacatt gtggggaggg accctgcagg aatgccccat
1621 cctgaaacca agaaggatct gtatgaaccc actcatgggg gcaaggtctt gagcatggcc
1681 cctggcctca cctctgtgga aatcattcca ttccgagtgg ctgcctacaa caaagccaaa
1741 aaagccatgg acttctatga tccagcaagg cacaatgagt ttgacttcat ctcaggaact
1801 cgaatgagga agctcgcccg ggaaggagag aatcccccag atggcttcat ggcccccaaa
1861 gcatggaagg tcctgacaga ttattacagg tccctggaga agaactaag
//