LOCUS AF152328 4605 bp mRNA linear HUM 22-JUL-1999
DEFINITION Homo sapiens protocadherin gamma A8 (PCDH-gamma-A8) mRNA, complete
cds.
ACCESSION AF152328
VERSION AF152328.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4605)
AUTHORS Wu,Q. and Maniatis,T.
TITLE A striking organization of a large family of human neural
cadherin-like cell adhesion genes
JOURNAL Cell 97 (6), 779-790 (1999)
PUBMED 10380929
REFERENCE 2 (bases 1 to 4605)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Human protocadherin genes
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 4605)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-1999) Department of Molecular and Cellular
Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA
02138, USA
FEATURES Location/Qualifiers
source 1..4605
/db_xref="H-InvDB:HIT000071754"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q31"
/tissue_type="brain"
gene 1..4605
/gene="PCDH-gamma-A8"
CDS 1..2799
/gene="PCDH-gamma-A8"
/function="cell-cell adhesion"
/note="member of the cadherin superfamily"
/codon_start=1
/product="protocadherin gamma A8"
/protein_id="AAD43722.1"
/translation="MAAPQSRPRRGELILLCALLGTLWEIGRGQIRYSVPEETDKGSF
VGNISKDLGLDPRKLAKHGVRIVSRGRTQLFALNPRSGSLITAGRIDREELCAQSPRC
LININTLVEDKGKLFGVEIEIIDINDNNPKFQVEDLEVKINEIAVPGARYPLPEAVDP
DVGVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLERALDREEEAAHHLVLTASDGG
KPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPPGTRLLTVTASDPDEGINGK
VAYKFRKINEKQTPLFQLNENTGEISIAKSLDYEECSFYEMEIQAEDVGALLGRTKLL
ISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPF
KLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPPLSTETQIALHVADINDNPP
TFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQVTYSVTEDTLQGAPLSSYISIN
SDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEILYPA
LPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTG
EVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLTELGSLKPSV
DPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWHKSRLLQDSGGRLVGVPASHF
VGVEEVQAFLQTYSQEVSLTADSRKSHLIFPQPNYADMLISQEGCEKNDSLLTSVDFH
EYKNEADHGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASA
SEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGK
APAGGNGNKKKSGKKEKK"
BASE COUNT 1070 a 1344 c 1198 g 993 t
ORIGIN
1 atggccgctc cacagagtcg ccccagacgc ggcgagctga tcctgctgtg cgcgctgctg
61 ggaacgctgt gggaaatcgg gaggggacag attcgctact ctgtgccaga agagacggac
121 aaaggctcct tcgtgggtaa tatctccaag gacctggggc tggacccccg gaagctggcg
181 aagcacggag tccgtatcgt ctccagaggt aggacgcagc tctttgctct gaacccgcgc
241 agcggcagct tgatcaccgc gggcaggata gatcgggagg agctctgcgc tcagagcccg
301 cggtgtctga taaatattaa caccctggtt gaggataaag gaaaactctt tggggtagaa
361 atagaaataa ttgatattaa cgataataac ccaaaattcc aggtcgaaga tctagaagta
421 aaaattaacg aaatcgcggt tcctggagca cgttatccac tcccagaagc tgttgacccg
481 gatgtgggcg tgaactccct ccagagctac cagctcagcc ccaatcacca cttctccctg
541 gacgtgcaga ctggagacaa tggagccata aacccagagc tggtgctgga gcgcgccctg
601 gacagggagg aagaggctgc tcaccacctg gtcctcacgg cctcggatgg cggcaagccg
661 cctcgctcta gcacagtgcg catccacgtg acagtgttgg atacaaatga caatgccccg
721 gtttttcctc acccgattta ccgagtgaaa gtccttgaga acatgccccc aggcacgcgg
781 ctgcttactg taacagccag cgacccggat gagggaatca acggaaaagt ggcatacaaa
841 ttccggaaaa ttaatgaaaa acaaactccg ttattccagc ttaatgaaaa tactggggaa
901 atatcaatag caaaaagtct agattatgaa gaatgttcat tttatgaaat ggaaatacaa
961 gccgaagatg tgggggcact tctggggagg accaaattgc tcatttcggt ggaagatgta
1021 aatgacaata gaccagaagt gatcattacg tctttgttta gcccagtgtt agaaaattct
1081 cttcccggga cagtaattgc cttcttgagt gtgcatgacc aagactctgg aaagaatggt
1141 caagttgtct gttacacacg tgataattta ccttttaaat tagaaaagtc aataggtaat
1201 tattatagat tagtgacaag gaaatatttg gaccgagaaa atgtctctat ctacaatatc
1261 acagtgatgg cctcagatct aggaacacca cctctgtcca ctgaaactca aatcgctctg
1321 cacgtggcag acattaacga caaccctcct actttccctc atgcctccta ctcagcgtat
1381 atcctagaga acaacctgag aggagcctcc atcttttcct tgactgcaca cgaccccgac
1441 agccaggaga atgcccaggt cacttactct gtgaccgagg acacgctgca gggggcgccc
1501 ctgtcctcgt atatctccat caactctgac accggtgtcc tgtatgcgct gcaatctttc
1561 gactatgagc agatccgaga cctgcagcta ctggtaacag ccagcgacag cggggacccg
1621 cccctcagca gcaacatgtc actgagcctg ttcgtgctgg accagaatga caacgcgccc
1681 gagatcctgt accccgccct ccccacagac ggttccactg gcgtggagct ggcgccccgc
1741 tccgcagagc gtggctacct ggtgaccaag gtggtggcgg tggacagaga ctcgggccag
1801 aacgcctggc tgtcctaccg cctgctcaag gccagcgagc cgggactctt ctcggtgggt
1861 ctgcacacgg gcgaggtgcg cacggcgcga gccctgctgg acagagatgc gctcaagcag
1921 agcctcgtgg tggccgtcca ggaccatggc cagccccctc tctccgccac tgtcacgctc
1981 accgtagccg tggctgacag catccccgaa gtcctgaccg agttgggcag tctgaagcct
2041 tcggtcgacc cgaacgattc gagccttaca ctctatctcg tggtggcagt ggctgccatc
2101 tcctgtgtct tcctcgcctt tgtcgctgtg cttctggggc tcaggctgag gcgctggcac
2161 aagtcacgcc tgctccagga ttccggtggc agattggtag gcgtgcctgc ctcacatttt
2221 gtgggtgttg aggaggtaca ggctttcctg cagacctatt cccaggaagt ctccctcacc
2281 gccgactcgc ggaagagtca cctgatcttt ccccagccca actacgcaga catgctcatc
2341 agtcaggagg gctgtgagaa aaatgattct ttgttaacat ccgtagattt tcatgaatat
2401 aagaatgaag ctgatcatgg tcagcaagcc ccgcccaaca cggactggcg tttctctcag
2461 gcccagagac ccggcaccag cggctcccaa aatggcgatg acaccggcac ctggcccaac
2521 aaccagtttg acacagagat gctgcaagcc atgatcttgg cgtccgccag tgaagctgct
2581 gatgggagct ccaccctggg agggggtgcc ggcaccatgg gattgagcgc ccgctacgga
2641 ccccagttca ccctgcagca cgtgcccgac taccgccaga atgtctacat cccaggcagc
2701 aatgccacac tgaccaacgc agctggcaag cgggatggca aggccccagc aggtggcaat
2761 ggcaacaaga agaagtcggg caagaaggag aagaagtaac atggaggcca ggccaagagc
2821 cacagggcgg cctctcccca accagcccag cttctcctta cctgcaccca ggcctcagag
2881 tttcagggct aacccccaga atactggtag gggccaaggc catgctcccc ttgggaaaca
2941 gaaacaagtg cccagtcagc acctacccct tcccccccag ggggttgaat atgcaaaagc
3001 agttccgctg ggaaccccca tccaatcaac tgctgtaccc atgggggtag tggggttact
3061 gtagacacca agaaccattt gccacacccc gtttagttac agctgaactc ctccatcttc
3121 caaatcaatc aggcccatcc atcccatgcc tccctcctcc ccaccccact ccaacagttc
3181 ctctttcccg agtaaggtgg ttggggtgtt gaagtaccaa gtaacctaca agcctcctag
3241 ttctgaaaag ttggaagggc atcatgacct cttggcctct cctttgattc tcaatcttcc
3301 cccaaagcat ggtttggtgc cagccccttc acctccttcc agagcccaag atcaatgctc
3361 aagttttgga ggacatgatc accatcccca tggtactgat gcttgctgga tttagggagg
3421 gcattttgct accaagcctc ttcccaacgc cctggggacc agtcttctgt tttgtttttc
3481 attgtttgac gtttccactg catgccttga cttcccccac ctcctcctca aacaagagac
3541 tccactgcat gttccaagac agtatggggt ggtaagataa ggaagggaag tgtgtggatg
3601 tggatggtgg gggcatggac aaagcttgac acatcaagtt atcaaggcct tggaggaggc
3661 tctgtatgtc ctcaggggac tgacaacatc ctccagattc cagccataaa ccaataacta
3721 ggctggaccc ttcccactac ataatagggc tcagcccagg cagccagctt tgggctgagc
3781 taacaggacc aatggattaa actggcattt cagtccaagg aagctcgaag caggtttagg
3841 accaggtccc cttgagaggt cagaggggcc tctgtgggtg ctgggtactc cagaggtgcc
3901 actggtggaa gggtcagcgg agccccagca ggaagggtgg gccagccagg ccattcttag
3961 tccctgggtt ggggaggcag ggagctaggg cagggaccaa atgaacagaa agtctcagcc
4021 caggatgggg cttcttcaac agggcccctg ccctcctgaa gcctcagtcc ttcaccttgc
4081 caggtgccgt ttctcttccg tgaaggccac tgcccaggtc cccagtgcgc cccctagtgg
4141 ccatagcctg gttaaagttc cccagtgcct ccttgtgcat agaccttctt ctcccacccc
4201 cttctgcccc tgggtccccg gccatccagc ggggctgcca gagaacccca gacctgccct
4261 tacagtagtg tagcgccccc tccctctttc ggctggtgta gaatagccag tagtgtagtg
4321 cggtgtgctt ttacgtgatg gcgggtgggc agcgggcggc gggctccgcg cagccgtctg
4381 tccttgatct gcccgcggcg gcccgtgttg tgttttgtgc tgtgtccacg cgctaaggcg
4441 accccctccc ccgtactgac ttctcctata agcgcttctc ttcgcatagt cacgtagctc
4501 ccaccccacc ctcttcctgt gtctcacgca agttttatac tctaatattt atatggcttt
4561 ttttcttcga caaaaaaata ataaaacgtt tcttctgaaa agctg
//