LOCUS AF150754 2377 bp mRNA linear HUM 25-JAN-2001
DEFINITION Homo sapiens 3'phosphoadenosine 5'-phosphosulfate synthase 2b
isoform mRNA, complete cds.
ACCESSION AF150754
VERSION AF150754.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2377)
AUTHORS Venkatachalam,K.V., Fuda,H. and Strott,C.A.
TITLE 3'-phosphoadenosine 5'-phosphosulfate synthase 2b isoform
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2377)
AUTHORS Venkatachalam,K.V., Fuda,H. and Strott,C.A.
TITLE Direct Submission
JOURNAL Submitted (12-MAY-1999) Steroid Regulation, National Institute of
Health, 9000 Rockville Pike, Bethesda, MD 20892-4510, USA
REFERENCE 3 (bases 1 to 2377)
AUTHORS Venkatachalam,K.V., Fuda,H. and Strott,C.A.
TITLE Direct Submission
JOURNAL Submitted (25-JAN-2001) Steroid Regulation, National Institute of
Health, 9000 Rockville Pike, Bethesda, MD 20892-4510, USA
REMARK Sequence update by submitter
COMMENT On Jan 25, 2001 this sequence version replaced AF150754.1.
FEATURES Location/Qualifiers
source 1..2377
/db_xref="H-InvDB:HIT000071578"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 81..1940
/note="PAPS synthase 2b b; ATP sulfurylase/adenosine
5'-phosphosulfate kinase 2b; bifunctional enzyme that
regulates production of the universal sulfonate donor
molecule, 3'-phosphoadenosine 5'-phosphosulfate"
/codon_start=1
/product="3'phosphoadenosine 5'-phosphosulfate synthase 2b
isoform"
/protein_id="AAF20366.2"
/translation="MSGIKKQKTENQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCT
VWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNRNLGFSPGDREENIRR
IAEVAKLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDV
KGLYKRARAGEIKGFTGIDSDYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVPY
TIIKDIHELFVPENKLDHVRAEAETLPSLSITKLDLQWVQVLSEGWATPLKGFMREKE
YLQVMHFDTLLDGMALPDGVINMSIPIVLPVSAEDKTRLEGCSKFVLAHGGRRVAILR
DAEFYEHRKEERCSRVWGTTCTKHPHIKMVMESGDWLVGGDLQVLEKIRWNDGLDQYR
LTPLELKQKCKEMNADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLG
GWTKDDDVPLDWRMKQHAAVLEEGVLDPKSTIVAIFPSPMLYAGPTEVQWHCRSRMIA
GANFYIVGRDPAGMPHPETKKDLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKAKKA
MDFYDPARHNEFDFISGTRMRKLAREGENPPDGFMAPKAWKVLTDYYRSLEKN"
polyA_site 2376
BASE COUNT 636 a 556 c 584 g 601 t
ORIGIN
1 ctgctgccgc cgccgccgcc gccgtccctg cgtccttcgg tctctgctcc cgggacccgg
61 ctccgccgca gccagccagc atgtcgggga tcaagaagca aaagacggag aaccagcaga
121 aatccaccaa tgtagtctat caggcccacc atgtgagcag gaataagaga gggcaagtgg
181 ttggaacaag gggtgggttc cgaggatgta ccgtgtggct aacaggtctc tctggtgctg
241 gaaaaacaac gataagtttt gccctggagg agtaccttgt ctcccatgcc atcccttgtt
301 actccctgga tggggacaat gtccgtcatg gccttaacag aaatctcgga ttctctcctg
361 gggacagaga ggaaaatatc cgccggattg ctgaggtggc taagctgttt gctgatgctg
421 gtctggtctg cattaccagc tttatttctc cattcgcaaa ggatcgtgag aatgcccgca
481 aaatacatga atcagcaggg ctgccattct ttgaaatatt tgtagatgca cctctaaata
541 tttgtgaaag cagagacgta aaaggcctct ataaaagggc cagagctggg gagattaaag
601 gatttacagg tattgattct gattatgaga aacctgaaac tcctgagcgt gtgcttaaaa
661 ccaatttgtc cacagtgagt gactgtgtcc accaggtagt ggaacttctg caagagcaga
721 acattgtacc ctatactata atcaaagata tccacgaact ctttgtgccg gaaaacaaac
781 ttgaccacgt ccgagctgag gctgaaactc tcccttcatt atcaattact aagctggatc
841 tccagtgggt ccaggttttg agcgaaggct gggccactcc cctcaaaggt ttcatgcggg
901 agaaggagta cttacaggtt atgcactttg acaccctgct agatggcatg gcccttcctg
961 atggcgtgat caacatgagc atccccattg tactgcccgt ctctgcagag gataagacac
1021 ggctggaagg gtgcagcaag tttgtcctgg cacatggtgg acggagggta gctatcttac
1081 gagacgctga attctatgaa cacagaaaag aggaacgctg ttcccgtgtt tgggggacaa
1141 catgtacaaa acacccccat atcaaaatgg tgatggaaag tggggactgg ctggttggtg
1201 gagaccttca ggtgctggag aaaataagat ggaatgatgg gttggaccaa taccgtctga
1261 cacctttgga gctcaaacag aaatgtaaag aaatgaatgc tgatgcggtg tttgcattcc
1321 agttgcgcaa tcctgtccac aatggccatg ccctgttgat gcaggacact cgccgcaggc
1381 tcctagagag gggctacaag cacccggtcc tcctactaca ccctctgggc ggctggacca
1441 aggatgacga tgtgcctcta gactggcgga tgaagcagca cgcggctgtg ctcgaggaag
1501 gggtcctgga tcccaagtca accattgttg ccatctttcc gtctcccatg ttatatgctg
1561 gccccacaga ggtccagtgg cactgcaggt cccggatgat tgcgggtgcc aatttctaca
1621 ttgtggggag ggaccctgca ggaatgcccc atcctgaaac caagaaggat ctgtatgaac
1681 ccactcatgg gggcaaggtc ttgagcatgg cccctggcct cacctctgtg gaaatcattc
1741 cattccgagt ggctgcctac aacaaagcca aaaaagccat ggacttctat gatccagcaa
1801 ggcacaatga gtttgacttc atctcaggaa ctcgaatgag gaagctcgcc cgggaaggag
1861 agaatccccc agatggcttc atggccccca aagcatggaa ggtcctgaca gattattaca
1921 ggtccctgga gaagaactaa gcctttgggt ccagagtttc tttctgaagt gctctttgat
1981 taccttttct atttttatga ttagatgctt tgtattaaat tgcttctcaa tgatgcattt
2041 taatctttta taatgaagta aaagttgtgt ctataattaa aaaaaaatat atatatatac
2101 acacacacat atacatacaa agtcaaactg aagaccaaat cttagcaggt aaaagcaata
2161 ttcttataca tttcataata aaattagctc tatgtatttt ctactgcacc tgagcaggca
2221 ggtcccagat ttcttaaggc tttgtttgac catgtgtcta gttacttgct gaaaagtgaa
2281 tatattttcc agcatgtctt gacaacctgt actcttccaa tgtcatttat cagttgtaaa
2341 atatatcaga ttgtgtcctc ttctgtacaa ttgacca
//