LOCUS AF141347 1657 bp mRNA linear HUM 21-SEP-2001
DEFINITION Homo sapiens hum-a-tub2 alpha-tubulin mRNA, complete cds.
ACCESSION AF141347
VERSION AF141347.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1657)
AUTHORS Crabtree,D.V., Ojima,I., Geng,X. and Adler,A.J.
TITLE Tubulins in the primate retina: evidence that xanthophylls may be
endogenous ligands for the paclitaxel-binding site
JOURNAL Bioorg. Med. Chem. 9 (8), 1967-1976 (2001)
PUBMED 11504633
REFERENCE 2 (bases 1 to 1657)
AUTHORS Crabtree,D.V. and Adler,A.J.
TITLE Direct Submission
JOURNAL Submitted (07-APR-1999) Schepens Eye Research Institute, 20
Staniford Street, Boston, MA 02114, USA
FEATURES Location/Qualifiers
source 1..1657
/db_xref="H-InvDB:HIT000071172"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="hum-a-tub2"
/sex="male; female"
/tissue_type="whole retina"
/note="Caucasians; death from trauma"
CDS 80..1435
/codon_start=1
/product="alpha-tubulin"
/protein_id="AAD33871.1"
/translation="MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGG
GDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANN
YARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD
YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLD
IERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVI
SAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAT
IKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD
HKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEE
Y"
BASE COUNT 402 a 426 c 418 g 411 t
ORIGIN
1 cctaagagtc gcgctgtaag aagcaacaac ctctcctctt cgtctccgcc atcagctcgg
61 cagtcgcgaa gcagcaacca tgcgtgagtg catctccatc cacgttggcc aggctggtgt
121 ccagattggc aatgcctgct gggagctcta ctgcctggaa cacggcatcc agcccgatgg
181 ccagatgcca agtgacaaga ccattggggg aggagatgat tccttcaaca ccttcttcag
241 tgagacgggg gctggcaagc atgtgccccg ggcagtgttt gtagacttgg aacccacagt
301 cattgatgaa gttcgcactg gcacctaccg ccagctcttc caccctgagc aacttatcac
361 aggcaaagaa gatgctgcca ataactatgc ccgagggcac tacaccattg gcaaggagat
421 cattgacctc gtgttggacc gaattcgcaa gctggccgac cagtgcacgg gtctccaggg
481 cttcttggtt ttccacagct ttggtggggg aactggttct gggttcacct cgctgctcat
541 ggaacgtctc tcagttgatt atggcaagaa gtccaagctg gagttctcta tttacccggc
601 gccccaggtt tccacagctg tagttgagcc ctacaactcc atcctcacca cccacaccac
661 cctggagcac tctgattgtg ccttcatggt agacaatgag gccatctatg acatctgtcg
721 tagaaacctc gatattgagc gtccaaccta tactaacctg aataggttaa taggtcaaat
781 tgtgtcctcc atcactgctt ccctgagatt tgatggagcc ctgaatgttg acctgacaga
841 attccagacc aacctggtgc cctatccccg catccacttc cctctggcca catatgcccc
901 tgtcatctct gctgagaaag cctaccatga acagctttct gtagcagaga tcaccaatgc
961 ttgctttgag ccagccaacc agatggtgaa atgtgaccct cgccatggta aatacatggc
1021 ttgctgcctg ttgtaccgtg gtgacgtggt tcccaaagat gtcaatgctg ccattgccac
1081 catcaagacc aagcgtacca tccagtttgt ggattggtgc cccactggct tcaaggttgg
1141 catcaactac cagcctccca ctgtggtgcc tggtggagac ctggccaagg tacagagagc
1201 tgtgtgcatg ctgagcaaca ccacagccat tgctgaggcc tgggctcgcc tggaccacaa
1261 gtttgacctg atgtatgcca aacgtgcctt tgttcactgg tacgttgggg aggggatgga
1321 ggaaggtgag ttttcagagg cccgtgagga catggctgcc cttgagaagg attatgagga
1381 ggttggtgtg gattctgttg aaggagaggg tgaggaagaa ggagaggaat actaaagtta
1441 aaacgtcaca aaggtgctgc ttttacaggg aagcttattc tgttttaaac attgaaaagt
1501 tgtggtctga tcagttaatt tgtatgtagc agtgtatgct ctcatataca attactgacc
1561 tatgctctaa aacatgaatg ctttgttaca gacccaagct gtccatttct gtgatgggtt
1621 ttgaataaag tattccctgt cttaaaaaaa aaaaaaa
//