LOCUS AF117946 3340 bp mRNA linear HUM 01-JAN-2000
DEFINITION Homo sapiens Link guanine nucleotide exchange factor II mRNA,
complete cds.
ACCESSION AF117946
VERSION AF117946.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3340)
AUTHORS Kawasaki,H., Chen,E.J., Springett,G.M., Graybiel,A.M. and
Housman,D.E.
TITLE A new family of Rap guanine nucleotide exchange factors
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3340)
AUTHORS Kawasaki,H., Chen,E.J., Springett,G.M., Graybiel,A.M. and
Housman,D.E.
TITLE Direct Submission
JOURNAL Submitted (06-JAN-1999) Center for Cancer Research/Dept. Brain and
Cognitive Sciences, Massachusetts Institute of Technology, 77
Massachusetts Avenue, Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..3340
/db_xref="H-InvDB:HIT000070127"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 127..1497
/note="Link-GEFII"
/codon_start=1
/product="Link guanine nucleotide exchange factor II"
/protein_id="AAF22003.1"
/translation="MEGPEGLGRKQACLAMLLHFLDTYQGLLQEEEGAGHIIKDLYLL
IMKDESLYQGLREDTLRLHQLVETVELKIPEENQPPSKQVKPLFRHFRRIDSCLQTRV
AFRGSDEIFCRVYMPDHSYVTIRSRLSASVQDILGSVTEKLQYSEEPAGREDSLILVA
VSSSGEKVLLQPTEDCVFTALGINSHLFACTRDSYEALVPLPEEIQVSPGDTEIHRVE
PEDVANHLTAFHWELFRCVHELEFVDYVFHGERGRRETANLELLLQRCSEVTHWVATE
VLLCEAPGKRAQLLKKFIKIAALCKQNQDLLSFYAVVMGLDNAAVSRLRLTWEKLPGK
FKNLFRKFENLTDPCRNHKSYREVISKMKPPVIPFVPLILKDLTFLHEGSKTLVDGLV
NIEKLHSVAEKVRTIRKYRSRPLCLDMEASPNHLQTKAYVRQFQVIDNQNLLFELSYK
LEANSQ"
BASE COUNT 673 a 982 c 899 g 786 t
ORIGIN
1 cgggcgccca gagacagcgc cgcctcagat atcctgctgg atgacattgt ccttacccat
61 tctctcttcc tcccgacgga gaaatttctg caggagctac accagtactt tgttcgggca
121 ggaggcatgg agggccctga agggctgggc cggaagcaag cctgtctagc catgcttctc
181 catttcttgg acacctacca ggggctgctt caagaggaag agggggccgg ccacatcatc
241 aaggatctat acctgctaat tatgaaggac gagtcccttt accagggcct ccgagaggac
301 actctgaggc tgcaccagct ggtggagacg gtggaactaa agattccaga ggagaaccag
361 ccacccagca agcaggtgaa gccactcttc cgccacttcc gccggataga ctcctgtctg
421 cagacccggg tggccttccg gggctctgat gagatcttct gccgtgtata catgcctgac
481 cactcttatg tgaccatacg cagccgcctt tcagcatctg tgcaggacat tctgggctct
541 gtgacggaga aacttcaata ttcagaggag cccgcggggc gtgaggattc cctcatcctg
601 gtagctgtgt cctcctctgg agagaaggtc cttctccagc ccactgagga ctgtgttttc
661 accgcactgg gcatcaacag ccacctgttt gcctgtactc gggacagcta tgaggctctg
721 gtgcccctcc ccgaggagat ccaggtctcc cctggagaca cagagatcca ccgagtggag
781 cctgaggacg ttgccaacca cctaactgcc ttccactggg agctgttccg atgtgtgcat
841 gagctggagt tcgtggacta cgtgttccac ggggagcgcg gccgccggga gacggccaac
901 ttggagctgc tgctgcagcg ctgcagcgag gtcacgcact gggtggccac cgaagtgctg
961 ctctgcgagg ccccgggcaa gcgcgcgcag ctgctcaaga agttcatcaa gatcgcggcc
1021 ctctgcaagc agaaccagga cctgctgtct ttctacgccg tggtcatggg gctggacaac
1081 gccgctgtca gccgccttcg actcacctgg gagaagctgc cagggaaatt caagaacttg
1141 tttcgcaaat ttgagaacct gacggacccc tgcaggaacc acaaaagcta ccgagaagtg
1201 atctccaaaa tgaagccccc tgtgattccc ttcgtgcctc tgatcctcaa agacctgact
1261 ttcctgcacg aagggagtaa gacccttgta gatggtttgg tgaacatcga gaagctgcat
1321 tcagtggccg aaaaagtgag gacaatccgc aaataccgga gccggcccct ttgcctggac
1381 atggaggcat cccccaatca cctgcagacc aaggcctatg tgcgccagtt tcaggtcatc
1441 gacaaccaga acctcctctt cgagctctcc tacaagctgg aggcaaacag tcagtgagag
1501 tggaggctcc agtcagaccc gccagatcct tgggcacctg gcactcaagc actttgcacg
1561 atgtctcaac caacatctga catctttccc gtggagcaac ttcctgctcc acgggaaaga
1621 ggtcgatgga tttacccctg gacccataag tctgttcatc ctgctgaagt cccctcccca
1681 ttgctccttc aagccaaaac tacactttgc tggttcctgt cccctctgag aaaggggata
1741 gaaagctcct tcctctatgt cctcccatcg agatctgttc tggggatgga gcttccaact
1801 tcctcttgca gcaggaaaga atgctgctca cccttctgtc ttgcagagtg ggattgtggg
1861 agggattggc agccttcttc tccaccacct gtccagcttc ttcctggtca gggctgggac
1921 ccccaggaat attatgttgc cgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
1981 tgtgtcttct tttagggagc aggagtgcat ctggtaattg agggtggatg ttgtgtgtgc
2041 tggggagggg tccttctgtt tggtgctacc cttgtctact ctgcccctgg atggtgcggg
2101 gtgctttctc cacccccaca ctccctgctc agctcctcgt gctgccctgc atgcccaggc
2161 ttgtgagcca aggtgctttt tggggcaggg agtagcagca ggtgggaggg gttacccatc
2221 agcccttgca agtcccccac tcaggcctct ggaaggtcca gggatgggct ctgatgagag
2281 ggtaaaagat gctcagggaa acacaggcct cagctgccta gaggaccctc cccctgcctt
2341 gcagtgggct cgggtagagc agtatcagga gctagggttg tctgctgccc acactcctgc
2401 tttttgggat atctaactgc taaggaggga gttgacatcc cccttctggc tcatgtgtct
2461 gacaccaaca acatggtctc cgtccctctc tcttagactc tccctttgtc ctccccatag
2521 agctggggtg gggtggatcc ctatactggg gcaggcagcc ccaaagtggg ggagggggat
2581 ggcagagact gtaaaggcgc cactggactc tggcaaggcc tttattacct ttactccctc
2641 cctctcccat caccagcctc aaggcctgag gggtgcaggg gctcctggca gctactgggt
2701 gaggtttcct ggcacagact cacccttctt tctggcacca ctctttccct tttgaagaga
2761 cagcaacagc cgtagcaaaa gcagctgctg ctcctgctat gagggtgtat atatttttta
2821 cccaaagctc tggaattgta catttatttt ttaaaactca aagagggaaa gagccttgta
2881 tcatatgtga acattgtatc ataggtaatg ttgtacagac ccttttatac agtgatctgt
2941 cttgttcctg cagcaaaaat cctctatgga cataggaggt gctgtgtccc atgccttctt
3001 gccctgacag tgtcccatgg gcccccttct gctccctgcc ccctccctgc tactgctgat
3061 gcactgtcct ctccctgcag cccctggctt cccagccttc ctcctgaccc cttccaacag
3121 ccttggaact ccagctgcca ccaccctctg ggtcggacac tgggacccac tggcccagtc
3181 ttggctgctg cttaccccta gccttgatgc ctgcccaggg acccccagcc ccctcccgtt
3241 gccctgcagc tttaacagag tgaaccatgt gtattgtaca ggcgcggttg tcattgcaga
3301 aaccgctggg tggagaagaa gccgataaag tctatgaatc
//