LOCUS       AF103563                 321 bp    mRNA    linear   HUM 26-JUL-2016
DEFINITION  Homo sapiens isolate donor Z clone Z31K immunoglobulin kappa light
            chain variable region mRNA, partial cds.
ACCESSION   AF103563
VERSION     AF103563.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   de Wildt,R.M., Hoet,R.M., van Venrooij,W.J., Tomlinson,I.M. and
            Winter,G.
  TITLE     Analysis of heavy and light chain pairings indicates that receptor
            editing shapes the human antibody repertoire
  JOURNAL   J. Mol. Biol. 285 (3), 895-901 (1999)
   PUBMED   9887257
REFERENCE   2  (bases 1 to 321)
  AUTHORS   de Wildt,R.M.T., Hoet,R.M.A., van Venrooij,W.J., Tomlinson,I.M. and
            Winter,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-1998) Centre for Protein Engineering, MRC, Hills
            Road, Cambridge CB2 2QH, UK
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="donor Z"
                     /db_xref="taxon:9606"
                     /clone="Z31K"
                     /cell_type="B cell"
                     /tissue_type="peripheral blood"
                     /note="isolated from patient with systemic lupus
                     erythematosus"
     CDS             <1..>321
                     /codon_start=3
                     /product="immunoglobulin kappa light chain variable
                     region"
                     /protein_id="AAD16623.1"
                     /translation="SLGERASINCKSSQSVLYSSNSKNYLAWYQQKPGQPPRLLIYWA
                     STRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYFCQQYYSSPLTFGGGTTVEIKRT
                     GQHH"
     V_region        <1..>321
BASE COUNT           80 a           86 c           82 g           73 t
ORIGIN      
        1 tgtctctggg cgagagggcc tccatcaact gcaagtccag ccagagtgtt ctatacagct
       61 ccaacagtaa gaactactta gcttggtatc aacaaaaacc aggacagcct ccaaggctgc
      121 tcatttactg ggcatctacc cgggaatccg gggtccctga ccgattcagt ggcagcgggt
      181 ctgggacaga tttcactctc accatcagca gcctgcaggc tgaagatgtg gcagtttatt
      241 tctgtcagca atattatagt agtcctctca ctttcggcgg agggaccacg gtggagatca
      301 aacgaactgg gcagcaccat t
//