LOCUS AF076464 1222 bp mRNA linear HUM 25-FEB-2003
DEFINITION Homo sapiens PhLOP1 mRNA, complete cds.
ACCESSION AF076464
VERSION AF076464.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1222)
AUTHORS Zhu,X. and Craft,C.M.
TITLE Interaction of phosducin and phosducin isoforms with a 26S
proteasomal subunit, SUG1
JOURNAL Mol. Vis. 4, 13 (1998)
PUBMED 9701609
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 1222)
AUTHORS Craft,C.M., Xu,J., Slepak,V.Z., Zhan-Poe,X., Zhu,X., Brown,B. and
Lolley,R.N.
TITLE PhLPs and PhLOPs in the phosducin family of G beta gamma binding
proteins
JOURNAL Biochemistry 37 (45), 15758-15772 (1998)
PUBMED 9843381
REFERENCE 3 (bases 1 to 1222)
AUTHORS Zhu,X. and Craft,C.M.
TITLE The carboxyl terminal domain of phosducin functions as a
transcriptional activator
JOURNAL Biochem. Biophys. Res. Commun. 270 (2), 504-509 (2000)
PUBMED 10753654
REFERENCE 4 (bases 1 to 1222)
AUTHORS Zhu,X. and Craft,C.M.
TITLE Modulation of CRX transactivation activity by phosducin isoforms
JOURNAL Mol. Cell. Biol. 20 (14), 5216-5226 (2000)
PUBMED 10866677
REFERENCE 5 (bases 1 to 1222)
AUTHORS Craft,C.M., Xu,J., Slepak,V.Z., Zhan,X., Zhu,X., Brown,B. and
Lolley,R.N.
TITLE Direct Submission
JOURNAL Submitted (07-JUL-1998) Cell and Neurobiology, Mary D. Allen
Laboratory for Vision Research, Doheny Eye Institute, USC School of
Medicine, 1333 San Pablo St. BMT 401, Los Angeles, CA 90033, USA
FEATURES Location/Qualifiers
source 1..1222
/db_xref="H-InvDB:HIT000066184"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="retina"
5'UTR 1..193
CDS 194..778
/note="G beta gamma binding protein"
/codon_start=1
/product="PhLOP1"
/protein_id="AAD43142.1"
/translation="MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQ
CMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSS
LTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEF
FAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE"
3'UTR 779..1222
regulatory 1146..1151
/regulatory_class="polyA_signal_sequence"
BASE COUNT 456 a 175 c 236 g 355 t
ORIGIN
1 caaatgtgtg gagatttatt ttataatagc aatgtgagga ataccttcct aattatgaca
61 aaaacaaaaa caacaacaaa aagaccattg aagaaaagga cccaaaggag taataaatga
121 ttggagaaag tttaaattag agagtcaaga cagtgattca attccaccta gcaagaagga
181 gattctcagg caaatgtctt ctcctcagag taggaatggc aaagattcaa aggaacgagt
241 cagcagaaag atgagcattc aagaatatga actaatccat aaagagaaag aggatgaaaa
301 ctgccttcgt aaataccgta gacagtgtat gcaggatatg caccagaagc tgagttttgg
361 gcctagatat gggtttgtgt atgagctgga aactggaaag caattcctag aaacaattga
421 aaaggaactg aagatcacca caattgttgt tcacatttat gaagatggta ttaagggttg
481 tgatgctcta aacagtagtt taacatgcct tgcagcagaa taccctatag ttaagttttg
541 taaaataaaa gcttcgaata caggtgctgg ggaccgcttt tccttagatg tacttcctac
601 actgctcatc tataaaggtg gggaactcat aagcaatttt attagtgttg ctgaacagtt
661 tgctgaagaa ttttttgctg gggatgtgga gtctttccta aatgaatatg ggttactacc
721 tgaaagagag gtacatgtcc tagagcatac caaaatagaa gaagaagatg ttgaatgaag
781 attcactatg tcaatatctc atgtttatcc tttaggtatt ggatgatggt tttggtagta
841 tctatattgc tttagtgaac acagagtatg ggcacggcta tgctaacttg acaaaaatga
901 ctgatgcaac aatcgagtta ttagcatttc ttagtattag ttactcaaat tgatacaatg
961 cttgactaca aaacgaagct gtcttcagca acattattag tagacaaaga ggatgtggat
1021 aatattatga catttttcaa aaatcccttt caagttatgt tttgtctttt ttactccatt
1081 ttccctcatc actgttatta tttggacttt tcaaattaca ttattcatta taattttctt
1141 tgtgtaataa aaatgaaatc tcatgaggaa ataaaaaaaa aaaaaaaaaa aaaaaaaaaa
1201 aaaaaaaaaa aaaaaaaaaa aa
//