LOCUS AF074016 5302 bp mRNA linear HUM 18-JUL-1998
DEFINITION Homo sapiens nonsense-mediated mRNA decay trans-acting factor mRNA,
complete cds.
ACCESSION AF074016
VERSION AF074016.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5302)
AUTHORS Page,M.F., Carr,B. and Anderson,P.
TITLE SMG-2 is a phosphoprotein
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 5302)
AUTHORS Page,M.F., Carr,B. and Anderson,P.
TITLE Direct Submission
JOURNAL Submitted (24-JUN-1998) Genetics, University of Wisconsin-Madison,
445 Henry Mall, Madison, WI 53706, USA
FEATURES Location/Qualifiers
source 1..5302
/db_xref="H-InvDB:HIT000065980"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p12-13.1"
CDS 228..3584
/note="RENT1; HUPF1; SMG2; phosphoprotein"
/codon_start=1
/product="nonsense-mediated mRNA decay trans-acting
factor"
/protein_id="AAC26788.1"
/translation="MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQT
QTPPGGPGGPGGGGAGGPGGAGAGAAAGQLDAQVGPEGILQNGAVDDSVAKTSQLLAE
LNFEEDEEDTYYTKDLPIHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHL
VRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSS
LKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSAT
LEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWD
LGLNKKRIAYFTLPKTDSDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIA
IELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEV
EDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYH
LARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIR
NMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPR
LAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQ
SLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWP
QPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEG
QRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDP
RRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFS
KPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSSMYFQTHDQIGMISAG
PSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRGTPKGKTGRGGRQKNRFGLPGP
SQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQPGLSQPELSQDSYLGDEFK
SQIDVALSQDSTYQGERAYQHGGVTGLSQY"
BASE COUNT 1097 a 1553 c 1643 g 1009 t
ORIGIN
1 ccgggcggct tcgaggggag ctgaggcgcg gaggggctcg gcggcagcgg cggcggctcg
61 gcactgttac ctctcggtcc ggctggcgcc ggggcgggcg gtttggtcct ttccgggcgc
121 gcgggggcga cagcggcagc gacccgaggc ctgcggccta ggcctcagcg cggcggcggg
181 ctcgagtgca gcgcggaacc ggcccgaggg ccctacccgg aggcaccatg agcgtggagg
241 cgtacgggcc cagctcgcag actctcactt tcctggacac ggaggaggcc gagctgcttg
301 gcgccgacac acagggctcc gagttcgagt tcaccgactt tactcttcct agccagacgc
361 agacgccccc cggcggcccc ggcggcccgg gcggtggcgg cgcgggaggc ccgggcggcg
421 cgggcgcggg cgctgcggcg ggacagctcg acgcgcaggt tgggcccgaa ggcatcctgc
481 agaacggggc tgtggacgac agtgtagcca agaccagcca gttgttggct gagttgaact
541 tcgaggaaga tgaagaagac acctattaca cgaaggacct ccccatacac gcctgcagtt
601 actgtggaat acacgatcct gcctgcgtgg tttactgtaa taccagcaag aagtggttct
661 gcaacggacg tggaaatact tctggcagcc acattgtaaa tcaccttgtg agggcaaaat
721 gcaaagaggt gaccctgcac aaggacgggc ccctggggga gacagtcctg gagtgctaca
781 actgcggctg tcgcaacgtc ttcctcctcg gcttcatccc ggccaaagct gactcagtgg
841 tggtgctgct gtgcaggcag ccctgtgcca gccagagcag cctcaaggac atcaactggg
901 acagctcgca gtggcagccg ctgatccagg accgctgctt cctgtcctgg ctggtcaaga
961 tcccctccga gcaggagcag ctgcgggcac gccagatcac ggcacagcag atcaacaagc
1021 tggaggagct gtggaaggaa aacccttctg ccacgctgga ggacctggag aagccggggg
1081 tggacgagga gccgcagcat gtcctcctgc ggtacgagga cgcctaccag taccagaaca
1141 tattcgggcc cctggtcaag ctggaggccg actacgacaa gaagctgaag gagtcccaga
1201 ctcaagataa catcactgtc aggtgggacc tgggccttaa caagaagaga atcgcctact
1261 tcactttgcc caagactgac tctgacatgc ggctcatgca gggggatgag atatgcctgc
1321 ggtacaaagg ggaccttgcg cccctgtgga aagggatcgg ccacgtcatc aaggtccctg
1381 ataattatgg cgatgagatc gccattgagc tgcggagcag cgtgggtgca cctgtggagg
1441 tgactcacaa cttccaggtg gattttgtgt ggaagtcgac ctcctttgac aggatgcaga
1501 gcgcattgaa aacgtttgcc gtggatgaga cctcggtgtc tggctacatc taccacaagc
1561 tgttgggcca cgaggtggag gacgtaatca tcaagtgcca gctgcccaag cgcttcacgg
1621 cgcagggcct ccccgacctc aaccactccc aggtttatgc cgtgaagact gtgctgcaaa
1681 gaccactgag cctgatccag ggcccgccag gcacggggaa gacggtgacg tcggccacca
1741 tcgtctacca cctggcccgg caaggcaacg ggccggtgct ggtgtgtgct ccgagcaaca
1801 tcgccgtgga ccagctaacg gagaagatcc accagacggg gctaaaggtc gtgcgcctct
1861 gcgccaagag ccgtgaggcc atcgactccc cggtgtcttt tctggccctg cacaaccaga
1921 tcaggaacat ggacagcatg cctgagctgc agaagctgca gcagctgaaa gacgagactg
1981 gggagctgtc gtctgccgac gagaagcggt accgggcctt gaagcgcacc gcagagagag
2041 agctgctgat gaacgcagat gtcatctgct gcacatgtgt gggcgccggt gacccgaggc
2101 tggccaagat gcagttccgc tccattttaa tcgacgaaag cacccaggcc accgagccgg
2161 agtgcatggt tcccgtggtc ctcggggcca agcagctgat ccttgtaggc gaccactgcc
2221 agctgggccc agtggtgatg tgcaagaagg cggccaaggc cgggctgtca cagtcgctct
2281 tcgagcgcct ggtggtgctg ggcatccggc ccatccgcct gcaggtccag taccggatgc
2341 accctgcact cagcgccttc ccatccaaca tcttctacga gggctccctc cagaatggtg
2401 tcactgcagc ggatcgtgtg aagaagggat ttgacttcca gtggccccaa cccgataaac
2461 cgatgttctt ctacgtgacc cagggccaag aggagattgc cagctcgggc acctcctacc
2521 tgaacaggac cgaggctgcg aacgtggaga agatcaccac gaagttgctg aaggcaggcg
2581 ccaagccgga ccagattggc atcatcacgc cctacgaggg ccagcgctcc tacctggtgc
2641 agtacatgca gttcagcggc tccctgcaca ccaagctcta ccaggaggtg gagatcgcca
2701 gtgtggacgc ctttcaggga cgcgagaagg acttcatcat cctgtcctgt gtgcgggcca
2761 acgagcacca aggcattggc tttttaaatg accccaggcg tctgaacgtg gccctgacca
2821 gagcaaggta tggcgtcatc attgtgggca acccgaaggc actatcaaag cagccgctct
2881 ggaaccacct gctgaactac tataaggagc agaaggtgct ggtggagggg ccgctcaaca
2941 acctgcgtga gagcctcatg cagttcagca agccacggaa gctggtcaac actatcaacc
3001 cgggagcccg cttcatgacc acagccatgt atgatgcccg ggaggccatc atcccaggct
3061 ccgtctatga tcggagcagc cagggccggc cttccagcat gtacttccag acccatgacc
3121 agattggcat gatcagtgcc ggccctagcc acgtggctgc catgaacatt cccatcccct
3181 tcaacctggt catgccaccc atgccaccgc ctggctattt tggacaagcc aacgggcctg
3241 ctgcagggcg aggcaccccg aaaggcaaga ctggtcgtgg gggacgccag aagaaccgct
3301 ttgggcttcc tggacccagc cagactaacc tccccaacag ccaagccagc caggatgtgg
3361 cgtcacagcc cttctctcag ggcgccctga cgcagggcta catctccatg agccagcctt
3421 cccagatgag ccagcccggc ctctcccagc cggagctgtc ccaggacagt taccttggtg
3481 acgagtttaa atcacaaatc gacgtggcgc tctcacagga ctccacgtac cagggagagc
3541 gggcttacca gcatggcggg gtgacggggc tgtcccagta ttaaaaggtg gcggcggaag
3601 agctaagcaa cgtggcttag tccatcagca tcttattctg ggtaataaaa aataaaaata
3661 aacggatacc tgttttccac tgctaaaact gaagcaccac tgtgtgagca acaggaaggg
3721 agagcgcacg agggagagga gccgaggccg agcgccccct gctggcccgc ggcggcgagg
3781 agcagaggga gcggaggagg ggccggcccg cgggagccgc ggccaccagg aggccccgct
3841 ccgtcccatc ggggctgcgg ccagggcgga gggaggaaga ccctcatctc agagtagccc
3901 tttcctctgt tcttttattt ctttttctct ttgattgaaa ggggactacg tcttagcagg
3961 aaaaaaaaac ttcgcatttc tgtgcccgag caggctcctt gcaaagacag cagcgtgcgg
4021 ggcagagccc cgggagggcg cgtctgtcca cgcctaccgg acgcgccgag gtcgcgctgc
4081 ctgtgttctc cgagggcctt catttaaaga aaataagggt gttttgggtt tttctctttg
4141 tttttttcaa gattctttta aaggagtact gaagaatatt ttcctaagtt tgtctctaaa
4201 atcttagcgg tggacctggg agatttgaga agcttccaga aacagtttaa acaagccagc
4261 gctactggag aagaggagca acacctgtgc cgcggccgga ggagttttgt tgttggtttt
4321 agcttccagt ggcttctttc tgcggggcat caggctgctg gggtagccgc ccgccgagcc
4381 tggaagctgc tcgttctccg ctggactcag aagccaagct gcttcccgcc tagactcggc
4441 gcagggcccc gcaccggtga ggaaggtgct tttggcccca ttgcgagggg ccttggccag
4501 gactggccct gtggccagga ggcgagaagg tggctgttcc cggattgacg gctttttccc
4561 gggggccttt ggaagatttg gtggaaggac aagagggcct gtccctgtcc ccgtccccag
4621 gaggtaccga cagtccctgt gctggttaga cacggagcgc tgcacaccga aagcccaaat
4681 tgggagctct gcctgccggc aactttgctg atggggtgat tgctgcttct ggggggtaag
4741 gaaacaagtt acagaaatta ccgcgttctg tgtgaaggga ctgagggtgt ggtgtcattg
4801 gcagaaggtc attttaggag agctgcccca gcccctcgaa cgcctggctt ggggtgtcat
4861 tctgcctggc ggccaggcct ccagcttccc ctgccccggg cctggggctg tcactggccc
4921 tgatccgaac acctccagat tccggcttct acatgggaca gacggggacg cacaggccac
4981 cttccttctg gcagggactc ttatttattc ccattgctct agggctttcg gtttcccctt
5041 cttccggtag gccgcgtaga ggcatgcacc gggtaggttt ccgcggtgac cccgcggcgg
5101 cctgagggac gctccctgcc ccatcccggc tgttgggctg ggccgctttg cctctgcttc
5161 gccctgtgct gtgttctcca gctttgtagc agcagccttg acaaacccag gcgcactgta
5221 ccaaggcaat gtaacttttg attttcggtc aatttaagtt cttttgtcac caaatattaa
5281 taaacagttt tgacttcaaa aa
//