LOCUS AF071538 1894 bp mRNA linear HUM 10-JAN-2000
DEFINITION Homo sapiens Ets transcription factor PDEF (PDEF) mRNA, complete
cds.
ACCESSION AF071538
VERSION AF071538.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1894)
AUTHORS Oettgen,P., Finger,E., Sun,Z., Akbarali,Y., Thamrongsak,U.,
Boltax,J., Grall,F., Dube,A., Weiss,A., Brown,L., Quinn,G., Kas,K.,
Endress,G., Kunsch,C. and Libermann,T.A.
TITLE PDEF, a novel prostate epithelium-specific ets transcription
factor, interacts with the androgen receptor and activates
prostate-specific antigen gene expression
JOURNAL J. Biol. Chem. 275 (2), 1216-1225 (2000)
PUBMED 10625666
REFERENCE 2 (bases 1 to 1894)
AUTHORS Libermann,T.A., Oettgen,P., Kunsch,C. and Finger,E.
TITLE Direct Submission
JOURNAL Submitted (10-JUN-1998) Medicine, Beth Israel Deaconess Medical
Center, 330 Brookline Ave., Boston, MA 02215, USA
FEATURES Location/Qualifiers
source 1..1894
/db_xref="H-InvDB:HIT000065861"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6p21.3"
/tissue_type="prostate"
gene 1..1894
/gene="PDEF"
CDS 416..1423
/gene="PDEF"
/note="prostate epithelium-specific"
/codon_start=1
/product="Ets transcription factor PDEF"
/protein_id="AAC95296.1"
/translation="MGSASPGLSSVSPSHLLLPPDTVSRTGLEKAAAGAVGLERRDWS
PSPPATPEQGLSAFYLSYFDMLYPEDSSWAAKAPGASSREEPPEEPEQCPVIDSQAPA
GSLDLVPGGLTLEEHSLEQVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLL
WTEHQYRLPPMGKAFQELAGKELCAMSEEQFRQRSPLGGDVLHAHLDIWKSAAWMKER
TSPGAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEK
GIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHP
I"
BASE COUNT 368 a 653 c 571 g 302 t
ORIGIN
1 gtctgacttc ctcccagcac attcctgcac tctgccgtgt ccacactgcc ccacagaccc
61 agtcctccaa gcctgctgcc agctccctgc aagcccctca ggttgggcct tgccacggtg
121 ccagcaggca gccctgggct gggggtaggg gactccctac aggcacgcag ccctgagacc
181 tcagagggcc accccttgag ggtggccagg cccccagtgg ccaacctgag tgctgcctct
241 gccaccagcc ctgctggccc ctggttccgc tggcccccca gatgcctggc tgagacacgc
301 cagtggcctc agctgcccac acctcttccc ggcccctgaa gttggcactg cagcagacag
361 ctccctgggc accaggcagc taacagacac agccgccagc ccaaacagca gcggcatggg
421 cagcgccagc ccgggtctga gcagcgtatc ccccagccac ctcctgctgc cccccgacac
481 ggtgtcgcgg acaggcttgg agaaggcggc agcgggggca gtgggtctcg agagacggga
541 ctggagtccc agtccacccg ccacgcccga gcagggcctg tccgccttct acctctccta
601 ctttgacatg ctgtaccctg aggacagcag ctgggcagcc aaggcccctg gggccagcag
661 tcgggaggag ccacctgagg agcctgagca gtgcccggtc attgacagcc aagccccagc
721 gggcagcctg gacttggtgc ccggcgggct gaccttggag gagcactcgc tggagcaggt
781 gcagtccatg gtggtgggcg aagtgctcaa ggacatcgag acggcctgca agctgctcaa
841 catcaccgca gatcccatgg actggagccc cagcaatgtg cagaagtggc tcctgtggac
901 agagcaccaa taccggctgc cccccatggg caaggccttc caggagctgg cgggcaagga
961 gctgtgcgcc atgtcggagg agcagttccg ccagcgctcg cccctgggtg gggatgtgct
1021 gcacgcccac ctggacatct ggaagtcagc ggcctggatg aaagagcgga cttcacctgg
1081 ggcgattcac tactgtgcct cgaccagtga ggagagctgg accgacagcg aggtggactc
1141 atcatgctcc gggcagccca tccacctgtg gcagttcctc aaggagttgc tactcaagcc
1201 ccacagctat ggccgcttca ttaggtggct caacaaggag aagggcatct tcaaaattga
1261 ggactcagcc caggtggccc ggctgtgggg catccgcaag aaccgtcccg ccatgaacta
1321 cgacaagctg agccgctcca tccgccagta ttacaagaag ggcatcatcc ggaagccaga
1381 catctcccag cgcctcgtct accagttcgt gcaccccatc tgagtgcctg gcccagggcc
1441 tgaaacccgc cctcaggggc ctctctcctg cctgccctgc ctcagccagg ccctgagatg
1501 ggggaaaacg ggcagtctgc tctgctgctc tgaccttcca gagcccaagg tcagggaggg
1561 gcaaccaact gccccagggg gatatgggtc ctctggggcc ttcgggacca tggggcaggg
1621 gtgcttcctc ctcaggccca gctgctcccc tggaggacag agggagacag ggctgctccc
1681 caacacctgc ctctgacccc agcatttcca gagcagagcc tacagaaggg cagtgactcg
1741 acaaaggcca caggcagtcc aggcctctct ctgctccatc cccctgcctc ccattctgca
1801 ccacacctgg catggtgcag ggagacatct gcacccctga gttgggcagc caggagtgcc
1861 cccgggaatg gataataaag atactagaga actg
//