LOCUS AF068626 4195 bp mRNA linear ROD 06-DEC-1999
DEFINITION Mus musculus DNA cytosine-5 methyltransferase 3B1 (Dnmt3b) mRNA,
alternatively spliced, complete cds.
ACCESSION AF068626
VERSION AF068626.2
KEYWORDS .
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 4195)
AUTHORS Okano,M., Xie,S. and Li,E.
TITLE Cloning and characterization of a family of novel mammalian DNA
(cytosine-5) methyltransferases
JOURNAL Nat. Genet. 19 (3), 219-220 (1998)
PUBMED 9662389
REFERENCE 2 (bases 1 to 4195)
AUTHORS Xie,S., Okano,M. and Li,E.
TITLE Direct Submission
JOURNAL Submitted (28-MAY-1998) CVRC, Mass. Gen. Hospital, 149 13th Street,
Charlestown, MA 02129, USA
REFERENCE 3 (bases 1 to 4195)
AUTHORS Okano,M., Chijiwa,T., Sasaki,H. and Li,E.
TITLE Direct Submission
JOURNAL Submitted (04-NOV-1999) CVRC, Mass. Gen. Hospital, 149 13th Street,
Charlestown, MA 02129, USA
REMARK Sequence update by submitter
COMMENT On Nov 18, 1999 this sequence version replaced AF068626.1.
FEATURES Location/Qualifiers
source 1..4195
/organism="Mus musculus"
/mol_type="mRNA"
/db_xref="taxon:10090"
/chromosome="2"
/map="84.0 cM"
gene 1..4195
/gene="Dnmt3b"
misc_feature 1..4195
/gene="Dnmt3b"
/note="similar to EST sequences deposited in GenBank
Accession Numbers AA116694, AA119979, AA177277, AA210568,
AA407106, and AA575617"
CDS 269..2848
/gene="Dnmt3b"
/function="de novo DNA methylation"
/note="alternatively spliced product; contains Cys-rich
region; C-terminal region is similar to corresponding
region of DNA cytosine-5 methyltransferase 3A"
/codon_start=1
/product="DNA cytosine-5 methyltransferase 3B1"
/protein_id="AAC40178.2"
/translation="MKGDSRHLNEEEGASGYEECIIVNGNFSDQSSDTKDAPSPPVLE
AICTEPVCTPETRGRRSSSRLSKREVSSLLNYTQDMTGDGDRDDEVDDGNGSDILMPK
LTRETKDTRTRSESPAVRTRHSNGTSSLERQRASPRITRGRQGRHHVQEYPVEFPATR
SRRRRASSSASTPWSSPASVDFMEEVTPKSVSTPSVDLSQDGDQEGMDTTQVDAESRD
GDSTEYQDDKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMPGMRWVQWFGDGKF
SEISADKLVALGLFSQHFNLATFNKLVSYRKAMYHTLEKARVRAGKTFSSSPGESLED
QLKPMLEWAHGGFKPTGIEGLKPNKKQPVVNKSKVRRSDSRNLEPRRRENKSRRRTTN
DSAASESPPPKRLKTNSYGGKDRGEDEESRERMASEVTNNKGNLEDRCLSCGKKNPVS
FHPLFEGGLCQSCRDRFLELFYMYDEDGYQSYCTVCCEGRELLLCSNTSCCRCFCVEC
LEVLVGAGTAEDAKLQEPWSCYMCLPQRCHGVLRRRKDWNMRLQDFFTTDPDLEEFEP
PKLYPAIPAAKRRPIRVLSLFDGIATGYLVLKELGIKVEKYIASEVCAESIAVGTVKH
EGQIKYVNDVRKITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFY
HLLNYTRPKEGDNRPFFWMFENVVAMKVNDKKDISRFLACNPVMIDAIKVSAAHRARY
FWGNLPGMNRPVMASKNDKLELQDCLEFSRTAKLKKVQTITTKSNSIRQGKNQLFPVV
MNGKDDVLWCTELERIFGFPAHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYF
ACE"
BASE COUNT 1061 a 1059 c 1125 g 950 t
ORIGIN
1 gaattccggg cgccggggtt aagcggccca agtaaacgta gcgcagcgat cggcgccgga
61 gattcgcgaa cccgacactc cgcgccgccc gccggccagg acccgcggcg cgatcgcggc
121 gccgcgctac agccagcctc acgacaggcc cgctgaggct tgtgccagac cttggaaacc
181 tcaggtatat acctttccag acgcgggatc tcccctcccc catccatagt gccttgggac
241 caaatccagg gccttctttc aggaaacaat gaagggagac agcagacatc tgaatgaaga
301 agagggtgcc agcgggtatg aggagtgcat tatcgttaat gggaacttca gtgaccagtc
361 ctcagacacg aaggatgctc cctcaccccc agtcttggag gcaatctgca cagagccagt
421 ctgcacacca gagaccagag gccgcaggtc aagctcccgg ctgtctaaga gggaggtctc
481 cagccttctg aattacacgc aggacatgac aggagatgga gacagagatg atgaagtaga
541 tgatgggaat ggctctgata ttctaatgcc aaagctcacc cgtgagacca aggacaccag
601 gacgcgctct gaaagcccgg ctgtccgaac ccgacatagc aatgggacct ccagcttgga
661 gaggcaaaga gcctccccca gaatcacccg aggtcggcag ggccgccacc atgtgcagga
721 gtaccctgtg gagtttccgg ctaccaggtc tcggagacgt cgagcatcgt cttcagcaag
781 cacgccatgg tcatcccctg ccagcgtcga cttcatggaa gaagtgacac ctaagagcgt
841 cagtacccca tcagttgact tgagccagga tggagatcag gagggtatgg ataccacaca
901 ggtggatgca gagagcagag atggagacag cacagagtat caggatgata aagagtttgg
961 aataggtgac ctcgtgtggg gaaagatcaa gggcttctcc tggtggcctg ccatggtggt
1021 gtcctggaaa gccacctcca agcgacaggc catgcccgga atgcgctggg tacagtggtt
1081 tggtgatggc aagttttctg agatctctgc tgacaaactg gtggctctgg ggctgttcag
1141 ccagcacttt aatctggcta ccttcaataa gctggtttct tataggaagg ccatgtacca
1201 cactctggag aaagccaggg ttcgagctgg caagaccttc tccagcagtc ctggagagtc
1261 actggaggac cagctgaagc ccatgctgga gtgggcccac ggtggcttca agcctactgg
1321 gatcgagggc ctcaaaccca acaagaagca accagtggtt aataagtcga aggtgcgtcg
1381 ttcagacagt aggaacttag aacccaggag acgcgagaac aaaagtcgaa gacgcacaac
1441 caatgactct gctgcttctg agtccccccc acccaagcgc ctcaagacaa atagctatgg
1501 cgggaaggac cgaggggagg atgaggagag ccgagaacgg atggcttctg aagtcaccaa
1561 caacaagggc aatctggaag accgctgttt gtcctgtgga aagaagaacc ctgtgtcctt
1621 ccaccccctc tttgagggtg ggctctgtca gagttgccgg gatcgcttcc tagagctctt
1681 ctacatgtat gatgaggacg gctatcagtc ctactgcacc gtgtgctgtg agggccgtga
1741 actgctgctg tgcagtaaca caagctgctg cagatgcttc tgtgtggagt gtctggaggt
1801 gctggtgggc gcaggcacag ctgaggatgc caagctgcag gaaccctgga gctgctatat
1861 gtgcctccct cagcgctgcc atggggtcct ccgacgcagg aaagattgga acatgcgcct
1921 gcaagacttc ttcactactg atcctgacct ggaagaattt gagccaccca agttgtaccc
1981 agcaattcct gcagccaaaa ggaggcccat tagagtcctg tctctgtttg atggaattgc
2041 aacggggtac ttggtgctca aggagttggg tattaaagtg gaaaagtaca ttgcctccga
2101 agtctgtgca gagtccatcg ctgtgggaac tgttaagcat gaaggccaga tcaaatatgt
2161 caatgacgtc cggaaaatca ccaagaaaaa tattgaagag tggggcccgt tcgacttggt
2221 gattggtgga agcccatgca atgatctctc taacgtcaat cctgcccgca aaggtttata
2281 tgagggcaca ggaaggctct tcttcgagtt ttaccacttg ctgaattata cccgccccaa
2341 ggagggcgac aaccgtccat tcttctggat gttcgagaat gttgtggcca tgaaagtgaa
2401 tgacaagaaa gacatctcaa gattcctggc atgtaaccca gtgatgatcg atgccatcaa
2461 ggtgtctgct gctcacaggg cccggtactt ctggggtaac ctacccggaa tgaacaggcc
2521 cgtgatggct tcaaagaatg ataagctcga gctgcaggac tgcctggagt tcagtaggac
2581 agcaaagtta aagaaagtgc agacaataac caccaagtcg aactccatca gacagggcaa
2641 aaaccagctt ttccctgtag tcatgaatgg caaggacgac gttttgtggt gcactgagct
2701 cgaaaggatc ttcggcttcc ctgctcacta cacggacgtg tccaacatgg gccgcggcgc
2761 ccgtcagaag ctgctgggca ggtcctggag tgtaccggtc atcagacacc tgtttgcccc
2821 cttgaaggac tactttgcct gtgaatagtt ctacccagga ctggggagct ctcggtcaga
2881 gccagtgccc agagtcaccc ctccctgaag gcacctcacc tgtccccttt ttagctcacc
2941 tgtgtggggc ctcacatcac tgtacctcag ctttctcctg ctcagtggga gcagagcctc
3001 ctggcccttg caggggagcc ccggtgctcc ctccgtgtgc acagctcaga cctggctgct
3061 tagagtagcc cggcatggtg ctcatgttct cttaccctga aactttaaaa cttgaagtag
3121 gtagtaagat ggctttcttt taccctcctg agtttatcac tcagaagtga tggctaagat
3181 accaaaaaaa caaacaaaaa cagaaacaaa aaacaaaaaa aaacctcaac agctctctta
3241 gtactcaggt tcatgctgca aaatcacttg agattttgtt tttaagtaac ccgtgctcca
3301 catttgctgg aggatgctat tgtgaatgtg ggctcagatg agcaaggtca aggggccaaa
3361 aaaaattccc cctctccccc caggagtatt tgaagatgat gtttatggtt taagtcttcc
3421 tggcaccttc cccttgcttt ggtacaaggg ctgaagtcct gttggtcttg tagcatttcc
3481 caggatgatg atgtcagcag ggatgacatc accaccttta gggcttttcc ctggcagggg
3541 cccatgtggc tagtcctcac gaagactgga gtagaatgtt tggagctcag gaagggtggg
3601 tggagtggcc ctcttccagg tgtgagggat acgaaggagg aagcttaggg aaatccattc
3661 cccactccct cttgccaaat gaggggccca gtccccaaca gctcaggtcc ccagaacccc
3721 ctagttcctc atgagaagct aggaccagaa gcacatcgtt ccccttatct gagcagtgtt
3781 tggggaacta cagtgaaaac cttctggaga tgttaaaagc tttttacccc acgatagatt
3841 gtgtttttaa ggggtgcttt ttttaggggc atcactggag ataagaaagc tgcatttcag
3901 aaatgccatc gtaatggttt ttaaacacct tttacctaat tacaggtgct attttataga
3961 agcagacaac acttcttttt atgactctca gacttctatt ttcatgttac catttttttt
4021 gtaactcgca aggtgtgggc ttttgtaact tcacaggtgt ggggagagac tgccttgttt
4081 caacagtttg tctccactgg tttctaattt ttaggtgcaa agatgacaga tgcccagagt
4141 ttacctttct ggttgattaa agttgtattt ctctaaaaaa aaaaaaaaaa aaaaa
//