LOCUS AF048731 4499 bp mRNA linear HUM 21-MAR-1998
DEFINITION Homo sapiens cyclin T2a mRNA, complete cds.
ACCESSION AF048731
VERSION AF048731.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4499)
AUTHORS Peng,J., Zhu,Y., Milton,J.T. and Price,D.H.
TITLE Identification of multiple cyclin subunits of human P-TEFb
JOURNAL Genes Dev. 12 (5), 755-762 (1998)
PUBMED 9499409
REFERENCE 2 (bases 1 to 4499)
AUTHORS Peng,J.M., Zhu,Y., Milton,J.T. and Price,D.H.
TITLE Direct Submission
JOURNAL Submitted (17-FEB-1998) Biochemistry, University of Iowa, 51 Newton
Road, Iowa City, IA 52242, USA
FEATURES Location/Qualifiers
source 1..4499
/db_xref="H-InvDB:HIT000064153"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 33..2024
/note="subunit of positive elongation transcription factor
b (P-TEFb); associates with CDK9 (PITALRE)"
/codon_start=1
/product="cyclin T2a"
/protein_id="AAC39665.1"
/translation="MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLI
QEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEH
VIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCT
QLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGK
HWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETP
LLGSSLVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSML
ATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSG
LHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDL
DVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLR
IPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSS
RHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVN
DASHNHHSKMSKSSKSSGGLRTSQHPRETGQEASGDQRS"
BASE COUNT 1430 a 823 c 882 g 1364 t
ORIGIN
1 tgaatgaagg agcgggcgga ggaggaattg tcatggcgtc gggccgtgga gcttcttctc
61 gctggttctt tactcgggaa cagctggaga acacgccgag ccgccgctgc ggagtggagg
121 cggataaaga gctctcgtgc cgccagcagg cggccaacct catccaggag atgggacagc
181 gtctcaatgt ctctcagctt acaataaaca ctgcgattgt ttatatgcac aggttttata
241 tgcaccattc tttcaccaaa ttcaacaaaa atataatatc gtctactgca ttatttttgg
301 ctgcaaaagt ggaagaacag gctcgaaaac ttgaacatgt tatcaaagta gcacatgctt
361 gtcttcatcc tctagagcca ctgctggata ctaaatgtga tgcttacctt caacagactc
421 aagaactggt tatacttgaa accataatgc tacaaactct aggttttgag atcaccattg
481 aacacccaca cacagatgtg gtgaaatgta cccagttagt aagagcaagc aaggatttgg
541 cacagacatc ctatttcatg gctaccaaca gtctgcatct tacaaccttc tgtcttcagt
601 acaaaccaac agtgatagca tgtgtatgca ttcatttggc ttgcaaatgg tccaattggg
661 agatccctgt atcaactgat ggaaagcatt ggtgggaata tgtggatcct acagttactc
721 tagaattatt agatgagcta acacatgagt ttctacaaat attggagaaa acgcctaata
781 ggttgaagaa gattcgaaac tggagggcta atcaggcagc taggaaacca aaagtagatg
841 gacaggtatc agagacacca cttcttggtt catctttggt ccagaattcc attttagtag
901 atagtgtcac tggtgtgcct acaaacccaa gttttcagaa accatctaca tcagcattcc
961 ctgcgccagt acctctaaat tcaggaaata tttctgttca agacagccat acatctgata
1021 atttgtcaat gctagcaaca ggaatgccaa gtacttcata cggtttatca tcacaccagg
1081 aatggcctca acatcaagac tcagcaagga cagaacagct atattcacag aaacaggaga
1141 catctttgtc tggtagccag tacaacatca acttccagca gggaccttct atatcactgc
1201 attcaggatt acatcacaga cctgacaaaa tttcagatca ttcttctgtt aagcaagaat
1261 atactcataa agcagggagc agtaaacacc atgggccaat ttccactact ccaggaataa
1321 ttcctcagaa aatgtcttta gataaatata gagaaaagcg taaactagaa actcttgatc
1381 tcgatgtaag ggatcattat atagctgccc aggtagaaca gcagcacaaa caagggcagt
1441 cacaggcagc cagcagcagt tctgttactt ctcccattaa aatgaaaata cctatcgcaa
1501 atactgaaaa atacatggca gataaaaagg aaaagagtgg gtcactgaaa ttacggattc
1561 caataccacc cactgataaa agcgccagta aagaagaact gaaaatgaaa ataaaagttt
1621 cttcttcaga aagacacagc tcttctgatg aaggcagtgg gaaaagcaaa cattcaagcc
1681 cacatattag cagagaccat aaggagaagc acaaggagca tccttcaagc cgccaccaca
1741 ccagcagcca caagcattcc cactcgcata gtggcagcag cagcggtggc agtaaacaca
1801 gtgccgacgg aataccaccc actgttctga ggagtcctgt tggcctgagc agtgatggca
1861 tttcctctag ctccagctct tcaaggaaga ggctgcatgt caatgatgca tctcacaacc
1921 accactccaa aatgagcaaa agttccaaaa gttcaggtgg gctacggaca tctcagcacc
1981 ctcgtgaaac tggacaagaa gccagtggag accaacggtc ctgatgccaa tcacgagtac
2041 agtacaagca gccagcatat ggactacaaa gacacattcg acatgctgga ctcactgtta
2101 agtgcccaag gaatgaacat gtaataattt gtttaggtca atttttcctt tactttttta
2161 atttaaaaat tgttagaatg gaaaaattcc ttctgatcta gcagtggtaa cccctgctgt
2221 tgctgccact gcttcaatat ttgtaagtgc tactttattc ttcattctga aaagaagaga
2281 ttatagtaaa caagtcttta tctccacata tgatagtgtt ataaatactg taaaggcatg
2341 gaaggtgcaa aactcagtat ttctacaatt gcagctaaga acattaggat gaatggctgg
2401 ctgcttctag gaatataaga tgcctcaagc attcattatt tatgatttga atactgtagc
2461 tattttttgt tgcttggctt ttgaatgagt gtaaattgtt ttcttttgtg tatttatact
2521 tgtatgtatg atttgcatgt ttcaatgata aagggataaa acagtatact gacaactgtt
2581 tacaagaaag tggagaaaat gtactacatt ttgtatgttt agatattacc gtaaatactc
2641 aggattggag ctgcttgtaa gtataacaat atacagaata ctttatttta tcttgtcaga
2701 gttccatcac tatctaaaac aaaggtgcaa ttttttatgt taaccttaaa tctagccctt
2761 actggaagcc actgataggg acattcacta ccagatgtgt gcagtgcagc agatggtcat
2821 ataacactgt gaggcactga attttgcctt cagaggttct gaccagattg gctgctgaaa
2881 tagcccctaa ctttctgaag gcttgaagag gaaaaaataa agtttacata ctcttgatgg
2941 aagtgcattt aaatgtttgt tggcttgttg cagttctatg aaacagagct gttaataatg
3001 gttatgtgga ttactgtgat ttgaaaacta aattcacaat aacttaccta gtagagattt
3061 agtgagttgt ttcctttaaa gaattttaca ctacatattt taatagtaaa cagggtcact
3121 ttcctttagc attcagaatg acaccatatt cttaaatata ctccttccct gaagcgtgtt
3181 tgtgtgtgat gccatatttc tttttcaggt aaatgtagtc ttccttataa aaatgaaatt
3241 aaacctatgc tctcaattct tttatattct aacaataaat aaaaaagaaa agattactga
3301 ctgtgcattg tacctgtatt tatagtttat ggttatcaga agctctgtaa gaaagaaaag
3361 gtcagctccc aggcaaacca gtagtggagg ttttacattt gtttgcacat ctcagtatat
3421 ttctgttgag gtaaagtttg cacagtcatc tgacttctga tcaagcatta gattttaact
3481 tgtttagatt ttgtcttaaa caccagtaat atggctcttg tttatcagct aatcttgaat
3541 ttattctgtg gtaaatcttt tgagttgctg agtatatttg agattgattg gattcaacct
3601 cttgttgaac tgaaaactta attttttctc tgtatttttg ttacaaagcc actgatacgt
3661 gcacaattgt aattaagtat gttgcagttg taaatattag agtttaatct catgctctac
3721 ctttatttag caattaccta atttgccagt agctttataa tttttaaaga taattgttca
3781 ttattttgtc aatgttattt gaacttgggg tacttaggag cctctttgta gggactgtgc
3841 ctaggtagca tgtcctaaca tttgttctgg tcttgcataa cttcagtatc tttgtcatta
3901 tatgtaactt tgttgctctg tatggcataa tattgtatcc ataaacatgg taattttgat
3961 acagttatac ttttacagtg gtacataatc caaggactag tatagaatta agctgagtgc
4021 aagatgaggg agggaagggc tttcttggta atttagatgt gaaacctcta cagagctatc
4081 atgtaaaaac tacatgaggt ggttgtgcta ctgtataatt gggggtgata ataccaggaa
4141 ttttaataag attttgtaaa gaatatccag aaaagtagtg aacttatttt cagtaggcat
4201 agaaaacaat gtgaatattt aaggtctgtg actatagtta aacttcacta agaatttgca
4261 gaattgtttt gagatgtgtg aataaaggta attttattga atcttcattg gtgctaatgt
4321 tggacagtta aaaagatagc tagtgtatat tgttatgggt cagtacttat tagtacttcc
4381 aaaattgaat ttgaaatgct atgtattcac ttttcactct gtaaatgtaa ttctttacaa
4441 tgactttatt tattaaaggg cagccagttg tcatttgtaa aaaaaaaaaa aaaaaaaaa
//