LOCUS AF017445 3144 bp mRNA linear HUM 12-NOV-1998
DEFINITION Homo sapiens GDP-L-fucose pyrophosphorylase (GFPP) mRNA, complete
cds.
ACCESSION AF017445
VERSION AF017445.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3144)
AUTHORS Pastuszak,I., Ketchum,C., Hermanson,G., Sjoberg,E.J., Drake,R. and
Elbein,A.D.
TITLE GDP-L-fucose pyrophosphorylase. Purification, cDNA cloning, and
properties of the enzyme
JOURNAL J. Biol. Chem. 273 (46), 30165-30174 (1998)
PUBMED 9804772
REFERENCE 2 (bases 1 to 3144)
AUTHORS Hermanson,G., Ketchum,C., Pastuszak,I., Drake,R. and Elbein,A.D.
TITLE Direct Submission
JOURNAL Submitted (05-AUG-1997) Molecular Biology, Cytel Corporation, 3525
John Hopkins Court, San Diego, CA 92121, USA
FEATURES Location/Qualifiers
source 1..3144
/db_xref="H-InvDB:HIT000062427"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3144
/gene="GFPP"
CDS 38..1822
/gene="GFPP"
/EC_number="2.7.7.30"
/function="catalyzes the formation of GDP-L-fucose from
GTP and L-fucose-1-phosphate"
/codon_start=1
/product="GDP-L-fucose pyrophosphorylase"
/protein_id="AAC73005.1"
/translation="MAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITA
ADEKQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGD
KWNSFTILLIHSGGYSQRLPNASALGKIFTALPLGNPIYQMLELKLAMYIDFPLNMNP
GILVTCADDIELYSIGEFEFIRFDKPGFTALAHPSSLTIGTTHGVFVLDPFDDLKHRD
LEYRSCHRFLHKPSIEKMYQFNAVCRPGNFCQQDFAGGDIADLKLDSDYVYTDSLFYM
DHKSAKMLLAFYEKIGTLSCEIDAYGDFLQALGPGATVEYTRNTSHVIKEESELVEMR
QRIFHLLKGTSLNVVVLNNSKFYHIGTTEEYLFYFTSDNSLKSELGLQSITFSIFPDI
PECSGKTSCIIQSILDSRCSVAPGSVVEYSRLGPDVSVGENCIISGSYILTKAALPAH
SFVCSLSLKMNRCLKYATMAFGVQDNLKKSVKTLSDIKLLQFFGVCFLSCLDVWNLKV
TEELFSGNKTCLSLWTARIFPVCSSLSDSVITSLKMLNAVKNKSAFSLNSYKLLSIEE
MLIYKDVEDMITYREQIFLEISLKSSLM"
BASE COUNT 999 a 509 c 601 g 1035 t
ORIGIN
1 gcgtgctgtg cggcgcggtc tcagggaagg tggggctatg gcagctgcta gggaccctcc
61 ggaagtatcg ctgcgagaag ccacccagcg aaaattgcgg aggttttccg agctaagagg
121 caaacttgta gcacgtggag aattctggga catagttgca ataacagcgg ctgatgaaaa
181 acaggaactt gcttacaacc aacagctgtc agaaaagctg aaaagaaagg agttacccct
241 tggagttcaa tatcacgttt ttgtggatcc tgctggagcc aaaattggaa atggaggatc
301 aacactttgt gcccttcaat gtttggaaaa gctatatgga gataaatgga attcttttac
361 catcttatta attcactctg gtggctacag tcaacgactt ccaaatgcaa gtgctctggg
421 aaaaattttc actgctttac ctcttggtaa ccccatttat cagatgctag aattaaagct
481 agccatgtac attgatttcc ccttaaatat gaatcctgga attctggtta cctgtgcaga
541 tgatattgaa ctttatagta ttggagaatt tgagtttatt aggtttgaca aacctggctt
601 tactgcttta gctcatcctt ctagtttgac gataggtacc acacatggag tatttgtctt
661 agatcctttt gatgatttaa aacatagaga ccttgaatac aggtcttgcc atcgtttcct
721 tcataagccc agcatagaaa agatgtatca gtttaatgct gtgtgtagac ctggaaattt
781 ttgtcaacag gactttgctg ggggtgacat tgccgatctt aaattagact ctgactatgt
841 ctacacagat agcctatttt atatggatca taaatcagca aaaatgttac ttgcttttta
901 tgaaaaaata ggcacactga gctgtgaaat agatgcctat ggtgactttc tgcaggcttt
961 gggacctgga gcaactgtgg agtacaccag aaacacatca catgtcatta aagaagagtc
1021 agagttggta gaaatgaggc agagaatatt tcatcttctt aaaggaacat cactaaatgt
1081 tgttgttctt aataactcca aattttatca cattggaaca accgaagaat atttgtttta
1141 ctttacctca gataacagtt taaagtcaga gctcggctta cagtccataa cttttagtat
1201 ctttccagat ataccagaat gctctggcaa aacatcctgt atcattcaaa gcatactgga
1261 ttcaagatgt tctgtggcac ctggctcagt tgtggagtat tccagattgg ggcctgatgt
1321 ttcagttggg gaaaactgca ttattagtgg ttcttacatc ctaacaaaag ctgccctccc
1381 cgcacattct tttgtatgtt ccttaagctt aaagatgaat agatgcttaa agtatgcaac
1441 tatggcattt ggagtgcaag acaacttgaa aaagagtgtg aaaacattgt cagatataaa
1501 gttacttcaa ttctttggag tctgtttcct gtcatgctta gatgtttgga atcttaaagt
1561 tacagaggaa ctgttctctg gtaacaagac atgtctgagt ttgtggactg cacgcatttt
1621 cccagtttgt tcttctttga gtgactcagt tataacatcc ctaaagatgt taaatgctgt
1681 taagaacaag tcagcattca gcctgaatag ctataagttg ctgtccattg aagaaatgct
1741 tatctacaaa gatgtagaag atatgataac ttacagggaa caaatttttc tagaaatcag
1801 tttaaaaagc agtttgatgt agagatattt taaatattgt acactttgcc tttttgagta
1861 acattccaga gataggtatt tttggtaggc tgtttcactg aactcagtta atgaaaactg
1921 tattaacata attgttgtag cataatatta atagtgcaaa agtacatata agtcattttg
1981 atgaaaaata ttccaagact aagttgagaa aagagatact attttggatg tgtatcagta
2041 tttttgtttt taataatgat tgatttgtgg agcattgttt tttcacataa ttagttttaa
2101 aggtaatttt ctaagcatac ctttggaatt tttccatctt ttttgaggct tttggtccag
2161 tgaagttcta agtattcact ggcacttctc tcctcaactg taattctatt tttaataata
2221 aaaatggcat actgtagggt cttcagagta gtgtaggaat actgtagaaa tactttttca
2281 gaaacgaatc catagctgac aaattcactc agtgcccaat atattgtgat tattttcgtt
2341 gataaagaac tagatacaaa gacctctgaa attgatgata aaatttgtat ctcattaatt
2401 ttatcaaaat gaaactaaaa gtacatatgt attatacact tgaacatgtg tttgtatatc
2461 tttaaaattt tcctttatgt ccattccata ggaagacaca catatgcaca caaaactcag
2521 ttatctgtgg gggaagtggt agtaataatt gagattcatc aataatcata taatttcact
2581 atagacatta cttgcattat ctcctatcag tccttctcac aaaacttcaa ttaccagatg
2641 aactgacttt agttttcatc ttattttttg tccacatgct ggtgatgctg agaaacaata
2701 attggcccaa atgcagacat caagaagcag gcaggaaaat ggaaaaactg agataataca
2761 caggtgataa acagtttcga gaaaataaaa attggctaga atctcaagtt atgtgtttct
2821 atattggtat aagcatataa gtgaaaagtc ttataagtgt aatagagaaa agatttgtca
2881 gtgtgttttt ttaaatgaaa taactagtct gtgctacttt atgtcaatat aaaaattggt
2941 aaactagaag taacttgtcc acaaccctca gttatgatac ttatgtgcgt gttttttttt
3001 ccaaagtttt tcccaaggag aagatacaaa tatatggtag ctattgttta aaaatgattg
3061 atttacttgc agatttttca gaggatgtta tgtctttgtc attcattaaa tgttcaaaat
3121 tgtagtttta aaaaaaaaaa aaaa
//