LOCUS AB022918 1469 bp mRNA linear HUM 14-MAY-1999
DEFINITION Homo sapiens ST3Gal VI mRNA for alpha2,3-sialyltransferase ST3Gal
VI, complete cds.
ACCESSION AB022918
VERSION AB022918.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1469)
AUTHORS Furukawa,K.
TITLE Direct Submission
JOURNAL Submitted (29-JAN-1999) to the DDBJ/EMBL/GenBank databases.
Contact:Koichi Furukawa
Nagoya University School of Medicine, Department of Biochemistry
II; 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-0065, Japan
REFERENCE 2
AUTHORS Okajima,T., Fukumoto,S., Miyazaki,H., Ishida,H., Kiso,M.,
Furukawa,K., Urano,T. and Furukawa,K.
TITLE Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal
VI) that sialylates type II lactosamine structures on
glycoproteins and glycolipids
JOURNAL J. Biol. Chem. 274, 11479-11486 (1999)
COMMENT
FEATURES Location/Qualifiers
source 1..1469
/cell_line="SK-MEL-37"
/cell_type="melanoma"
/db_xref="H-InvDB:HIT000058758"
/db_xref="taxon:9606"
/mol_type="mRNA"
/note="vector:pCDM8"
/organism="Homo sapiens"
CDS 259..1254
/codon_start=1
/function="synthesize sialylparagloboside"
/gene="ST3Gal VI"
/note="novel alpha2,3-sialyltransferase"
/product="alpha2,3-sialyltransferase ST3Gal VI"
/protein_id="BAA77609.1"
/transl_table=1
/translation="MRGYLVAIFLSAVFLYYVLHCILWGTNVYWVAPVEMKRRNKIQP
CLSKPAFASLLRFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQ
SCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRR
TTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALN
LIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHL
AGFKYNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLTQD"
BASE COUNT 414 a 306 c 311 g 438 t
ORIGIN
1 tcagtgttta cttctgccgc ctgccagccg ggcggggaag gggagtaccc ggccacccct
61 cactttagct cctgcagctt tccaaacaaa ccagggcggg atgggagtgt cttcttggct
121 gtggaaatcg atcctcctac cttgtcctga agccacccgc cgcctttcct cgtccctccc
181 ttcgcggtga ttttccggtc ccggcgcccg gcgagggcgc gcggctggtg tccgccccgc
241 ccgaaaggtg agccagccat gagagggtat cttgtggcca tattcctgag tgctgtcttc
301 ctctattatg tactgcattg catattatgg ggaacgaatg tctattgggt ggcacctgtg
361 gaaatgaaac ggagaaataa gatccagcct tgtttatcaa agccagcttt tgcctctctg
421 ctgaggtttc atcagtttca cccttttctg tgtgcggctg attttagaaa gattgcttcc
481 ttgtatggta gcgataagtt tgatttgccc tatgggatga gaacatcagc ggaatatttt
541 cgacttgctc tttcaaaact gcagagttgt gatctctttg atgagtttga caacataccc
601 tgtaaaaagt gtgtggtggt tggtaatgga ggagttttga agaataagac attaggagaa
661 aaaatcgact cctatgatgt aataataaga atgaataatg gtcctgtttt aggacatgaa
721 gaagaagttg ggagaaggac aaccttccga cttttttatc cagaatctgt tttttcagat
781 cctattcaca atgaccctaa tacgacagtg attctcactg cttttaagcc acatgattta
841 aggtggctgt tggaattgtt gatgggtgac aaaataaaca ctaatggttt ttggaagaaa
901 ccagccttaa acctgattta taaaccttat caaatccgaa tattagatcc tttcattatc
961 agaacagcag cttatgaact gcttcatttt ccaaaagtgt ttcccaaaaa tcagaaacct
1021 aaacacccaa caacaggaat tattgccatc acattggcgt tttacatatg tcacgaagtt
1081 cacctagctg gttttaaata caacttttct gacctcaaga gtcctttgca ctactatggg
1141 aatgccacca tgtctttgat gaataagaac gcgtatcaca atgtgactgc agagcagctc
1201 tttttgaagg acattataga aaaaaacctc gtaatcaact tgactcaaga ttgactctac
1261 agactcagaa gatgatgcta acagtgttag ttttattttt gtactgcaat ttttagttta
1321 aaatatgttg gatgcactcg tcaaataatt atgtatactg tctgttgctg cctggtgatt
1381 cataaccacc agcttaattt ctgtgaatac tgtatattta acttatgaaa accaagaaat
1441 taaagataac aggaaaaaaa aaaaaaaaa
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