LOCUS SIU02179.1 354 aa PRT BCT 25-MAY-2020
DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible
lipid transfer protein or keto acyl-coa thiolase ltp4
protein.
ACCESSION LT708304-3593
PROTEIN_ID SIU02179.1
SOURCE Mycobacterium tuberculosis variant bovis AF2122/97
ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Malone K.M.
JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine, University College
Dublin, D4, Ireland
REFERENCE 2
AUTHORS Malone M K., Farrell D., Malone K.
JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine,, University College
Dublin, D4, Ireland
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis variant bovis
AF2122/97"
/chromosome="Mycobacterium_bovis_AF212297"
/isolate="AF2122/97"
/mol_type="genomic DNA"
/isolation_source="Mycobacterium bovis subsp. bovis strain
AF2122/97. This strain is a fully virulent strain that was
isolated in 1997 in the UK from a cow suffering necrotic
lesions in lung and bronchomediastinal lymph nodes. The
strain was also reported to infect and persist in badgers
that are considered to be a significant source of bovine
infection."
/db_xref="taxon:233413"
protein /transl_table=11
/gene="ltp4"
/locus_tag="BQ2027_MB3552"
/note="Mb3552, -, len: 354 aa. Equivalent to Rv3522, len:
354 aa, from Mycobacterium tuberculosis strain H37Rv,
(99.7% identity in 354 aa overlap). Possible lipid carrier
protein or keto acyl-CoA thiolase (EC 2.3.1.16), similar
to several e.g. O30103|AF0134 3-KETOACYL-COA THIOLASE
(ACAB-4) from Archaeoglobus fulgidus (398 aa) FASTA
scores: opt: 352, E(): 5.3e-15, (30.45% identity in 381 aa
overlap); O29295|AF0967 3-KETOACYL-COA THIOLASE (ACAB-9)
from Archaeoglobus fulgidus (400 aa) FASTA scores: opt:
312, E(): 1.8e-12, (28.05% identity in 367 aa overlap);
O29294|AF0968 3-KETOACYL-COA THIOLASE (ACAB-10) from
Archaeoglobus fulgidus (388 aa), FASTA scores: opt: 293,
E(): 2.9e-11, (25.9% identity in 309 aa overlap);
O58409|PH0676 LONG HYPOTHETICAL NONSPECIFIC LIPID-TRANSFER
PROTEIN (ACETHYL CoA SYNTHETASE) (EC 6.2.1.-) from
Pyrococcus horikoshii (389 aa), FASTA scores: opt: 292,
E(): 3.3e-11, (25.8% identity in 368 aa overlap);
Q9Y9A3|APE2382 LONG HYPOTHETICAL NON SPECIFIC
LIPID-TRANSFER PROTEIN from Aeropyrum pernix (360 aa)
FASTA scores: opt: 270, E(): 7.8e-10, (27.25% identity in
363 aa overlap); Q9YDI4|APE0929 LONG HYPOTHETICAL
NONSPECIFIC LIPID-TRANSFER PROTEIN from Aeropyrum pernix
(400 aa), FASTA scores: opt: 258, E(): 4.9e-09, (26.45%
identity in 306 aa overlap); etc. Contains PS00017
ATP/GTP-binding site motif A (P-loop). Protein product
from Mb3552 detected using shotgun mass spectrometry and
SWATH mass spectrometry. Mb3552 found to be expressed
during exponential growth in Sauton's minimal media by
RNA-sequencing."
/db_xref="GOA:A0A1R3Y4H2"
/db_xref="InterPro:IPR016039"
/db_xref="UniProtKB/TrEMBL:A0A1R3Y4H2"
BEGIN
1 MSVRDIAVVG FAHAPHVRRT DGTTNGVEML MPCFAQLYDE LGITKADIGF WCSGSSDYLA
61 GRAFSFISAI DSIGAVPPIN ESHVEMDAAW ALYEAYIKLL TGEVDTALVY GFGKSSAGTL
121 RRVLSRQTDP YTVAPLWPDS VSMAGLQARL GLDSGKWTHE QMARVAFDSF TNARRVDSVE
181 PPITVGELLA RPFFADPLRR HDIAPITDGA AAVVLAADNR ARELRENPAW ITGIEHRIES
241 PALGARDITE SPSTKLAAKI ATGGHTGDID VAEIHGPFTH QHLIVAEAIR IPGKTKVNPS
301 GGPLAANPMF AAGLERIGFA AQHIWDGSAR RVLAHATSGP ALQQNLVAVM EGRG
//