LOCUS CCP46453.1 431 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable conserved integral
membrane protein protein.
ACCESSION AL123456-3731
PROTEIN_ID CCP46453.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/locus_tag="Rv3630"
/note="Rv3630, (MTCY15C10.22c), len: 431 aa. Probable
conserved integral membrane, highly similar to
P71789|YF10_MYCTU|Rv1510|MTCY277.32 hypothetical 44.3 KDA
protein from Mycobacterium tuberculosis (432 aa) FASTA
scores: opt: 1940, E(): 2.3e-103, (70.75% identity in 424
aa overlap). Note that N-terminal end is highly similar to
AAK45825|MT1558 hypothetical 18.1 KDA protein from
Mycobacterium tuberculosis strain CDC1551 (172 aa) FASTA
scores: opt: 649, E(): 4.2e-30, (61.65% identity in 167 aa
overlap); and C-terminal end is highly similar to
AAK45826|MT1560 hypothetical 25.8 KDA protein from
Mycobacterium tuberculosis strain CDC1551 (256 aa), FASTA
scores: opt: 1269, E(): 2.6e-65, (76.7% identity in 253 aa
overlap). Contains PS00639 Eukaryotic thiol (cysteine)
proteases histidine active site, so could be a protease."
/db_xref="EnsemblGenomes-Gn:Rv3630"
/db_xref="EnsemblGenomes-Tr:CCP46453"
/db_xref="GOA:P9WKX9"
/db_xref="UniProtKB/Swiss-Prot:P9WKX9"
/inference="protein motif:PROSITE:PS00639"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MAVGAAAVTE VGDTASPVGS SGASGGAIAS GSVARVGTAA AVTALCGYAV IYLAARNLAP
61 NGFSVFGVFW GAFGLVTGAA NGLLQETTRE VRSLGYLDVS ADGRRTHPLR VSGMVGLGSL
121 VVIAGSSPLW SGRVFAEARW LSVALLSIGL AGFCLHATLL GMLAGTNRWT QYGALMVADA
181 VIRVVVAAAT FVIGWQLVGF IWATVAGSVA WLIMLMTSPP TRAAARLMTP GATATFLRGA
241 AHSIIAAGAS AILVMGFPVL LKLTSNELGA QGGVVILAVT LTRAPLLVPL TAMQGNLIAH
301 FVDERTERIR ALIAPAALIG GVGAVGMLAA GVVGPWIMRV AFGSEYQSSS ALLAWLTAAA
361 VAIAMLTLTG AAAVAAALHR AYSLGWVGAT VGSGLLLLLP LSLETRTVVA LLCGPLVGIG
421 VHLVALARTD E
//