LOCUS       CCP46453.1               431 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable conserved integral
            membrane protein protein.
ACCESSION   AL123456-3731
PROTEIN_ID  CCP46453.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /locus_tag="Rv3630"
                     /note="Rv3630, (MTCY15C10.22c), len: 431 aa. Probable
                     conserved integral membrane, highly similar to
                     P71789|YF10_MYCTU|Rv1510|MTCY277.32 hypothetical 44.3 KDA
                     protein from Mycobacterium tuberculosis (432 aa) FASTA
                     scores: opt: 1940, E(): 2.3e-103, (70.75% identity in 424
                     aa overlap). Note that N-terminal end is highly similar to
                     AAK45825|MT1558 hypothetical 18.1 KDA protein from
                     Mycobacterium tuberculosis strain CDC1551 (172 aa) FASTA
                     scores: opt: 649, E(): 4.2e-30, (61.65% identity in 167 aa
                     overlap); and C-terminal end is highly similar to
                     AAK45826|MT1560 hypothetical 25.8 KDA protein from
                     Mycobacterium tuberculosis strain CDC1551 (256 aa), FASTA
                     scores: opt: 1269, E(): 2.6e-65, (76.7% identity in 253 aa
                     overlap). Contains PS00639 Eukaryotic thiol (cysteine)
                     proteases histidine active site, so could be a protease."
                     /db_xref="EnsemblGenomes-Gn:Rv3630"
                     /db_xref="EnsemblGenomes-Tr:CCP46453"
                     /db_xref="GOA:P9WKX9"
                     /db_xref="UniProtKB/Swiss-Prot:P9WKX9"
                     /inference="protein motif:PROSITE:PS00639"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MAVGAAAVTE VGDTASPVGS SGASGGAIAS GSVARVGTAA AVTALCGYAV IYLAARNLAP
       61 NGFSVFGVFW GAFGLVTGAA NGLLQETTRE VRSLGYLDVS ADGRRTHPLR VSGMVGLGSL
      121 VVIAGSSPLW SGRVFAEARW LSVALLSIGL AGFCLHATLL GMLAGTNRWT QYGALMVADA
      181 VIRVVVAAAT FVIGWQLVGF IWATVAGSVA WLIMLMTSPP TRAAARLMTP GATATFLRGA
      241 AHSIIAAGAS AILVMGFPVL LKLTSNELGA QGGVVILAVT LTRAPLLVPL TAMQGNLIAH
      301 FVDERTERIR ALIAPAALIG GVGAVGMLAA GVVGPWIMRV AFGSEYQSSS ALLAWLTAAA
      361 VAIAMLTLTG AAAVAAALHR AYSLGWVGAT VGSGLLLLLP LSLETRTVVA LLCGPLVGIG
      421 VHLVALARTD E
//