LOCUS CCP45640.1 900 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable translation
initiation factor if-2 InfB protein.
ACCESSION AL123456-2918
PROTEIN_ID CCP45640.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="infB"
/locus_tag="Rv2839c"
/note="Rv2839c, (MTCY16B7.03), len: 900 aa. Probable
infB,translation initiation factor if-2, highly similar,
but in part, to Q9Z5I9|IF2_MYCLE|ML1556|MLCB596.14
translation initiation factor if-2 from Mycobacterium
leprae (924 aa),FASTA scores: opt: 4548, E(): 2.4e-132,
(83.6% identity in 933 aa overlap). Also similar in part
to others e.g. Q9K3E2|SC5H4.30 from Streptomyces
coelicolor (835 aa),FASTA scores: opt: 2559, E(): 1.3e-71,
(59.9% identity in 833 aa overlap); P17889|IF2_BACSU|INFB
from Bacillus subtilis (716 aa), FASTA scores: opt: 1782,
E(): 6.6e-48,(46.65% identity in 686 aa overlap);
P02995|IF2_ECOLI|INFB|SSYG|B3168|Z4529|ECS4049 from
Escherichia coli strains O157:H7 and K12 (890 aa), FASTA
scores: opt: 1708, E(): 1.3e-45, (46.2% identity in 662 aa
overlap); etc. Contains PS00017 ATP/GTP-binding site motif
A (P-loop). Belongs to the if-2 family."
/db_xref="EnsemblGenomes-Gn:Rv2839c"
/db_xref="EnsemblGenomes-Tr:CCP45640"
/db_xref="GOA:P9WKK1"
/db_xref="InterPro:IPR000178"
/db_xref="InterPro:IPR000795"
/db_xref="InterPro:IPR005225"
/db_xref="InterPro:IPR006847"
/db_xref="InterPro:IPR009000"
/db_xref="InterPro:IPR015760"
/db_xref="InterPro:IPR023115"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR036925"
/db_xref="UniProtKB/Swiss-Prot:P9WKK1"
/inference="protein motif:PROSITE:PS00017"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MAAGKARVHE LAKELGVTSK EVLARLSEQG EFVKSASSTV EAPVARRLRE SFGGSKPAPA
61 KGTAKSPGKG PDKSLDKALD AAIDMAAGNG KATAAPAKAA DSGGAAIVSP TTPAAPEPPT
121 AVPPSPQAPH PGMAPGARPG PVPKPGIRTP RVGNNPFSSA QPADRPIPRP PAPRPGTARP
181 GVPRPGASPG SMPPRPGGAV GGARPPRPGA PRPGGRPGAP GAGRSDAGGG NYRGGGVGAA
241 PGTGFRGRPG GGGGGRPGQR GGAAGAFGRP GGAPRRGRKS KRQKRQEYDS MQAPVVGGVR
301 LPHGNGETIR LARGASLSDF ADKIDANPAA LVQALFNLGE MVTATQSVGD ETLELLGSEM
361 NYNVQVVSPE DEDRELLESF DLSYGEDEGG EEDLQVRPPV VTVMGHVDHG KTRLLDTIRK
421 ANVREAEAGG ITQHIGAYQV AVDLDGSQRL ITFIDTPGHE AFTAMRARGA KATDIAILVV
481 AADDGVMPQT VEAINHAQAA DVPIVVAVNK IDKEGADPAK IRGQLTEYGL VPEEFGGDTM
541 FVDISAKQGT NIEALEEAVL LTADAALDLR ANPDMEAQGV AIEAHLDRGR GPVATVLVQR
601 GTLRVGDSVV AGDAYGRVRR MVDEHGEDVE VALPSRPVQV IGFTSVPGAG DNFLVVDEDR
661 IARQIADRRS ARKRNALAAR SRKRISLEDL DSALKETSQL NLILKGDNAG TVEALEEALM
721 GIQVDDEVVL RVIDRGVGGI TETNVNLASA SDAVIIGFNV RAEGKATELA SREGVEIRYY
781 SVIYQAIDEI EQALRGLLKP IYEENQLGRA EIRALFRSSK VGLIAGCLVT SGVMRRNAKA
841 RLLRDNIVVA ENLSIASLRR EKDDVTEVRD GFECGLTLGY ADIKEGDVIE SYELVQKERA
//