LOCUS CCP45640.1 900 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Probable translation initiation factor if-2 InfB protein. ACCESSION AL123456-2918 PROTEIN_ID CCP45640.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /gene="infB" /locus_tag="Rv2839c" /note="Rv2839c, (MTCY16B7.03), len: 900 aa. Probable infB,translation initiation factor if-2, highly similar, but in part, to Q9Z5I9|IF2_MYCLE|ML1556|MLCB596.14 translation initiation factor if-2 from Mycobacterium leprae (924 aa),FASTA scores: opt: 4548, E(): 2.4e-132, (83.6% identity in 933 aa overlap). Also similar in part to others e.g. Q9K3E2|SC5H4.30 from Streptomyces coelicolor (835 aa),FASTA scores: opt: 2559, E(): 1.3e-71, (59.9% identity in 833 aa overlap); P17889|IF2_BACSU|INFB from Bacillus subtilis (716 aa), FASTA scores: opt: 1782, E(): 6.6e-48,(46.65% identity in 686 aa overlap); P02995|IF2_ECOLI|INFB|SSYG|B3168|Z4529|ECS4049 from Escherichia coli strains O157:H7 and K12 (890 aa), FASTA scores: opt: 1708, E(): 1.3e-45, (46.2% identity in 662 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the if-2 family." /db_xref="EnsemblGenomes-Gn:Rv2839c" /db_xref="EnsemblGenomes-Tr:CCP45640" /db_xref="GOA:P9WKK1" /db_xref="InterPro:IPR000178" /db_xref="InterPro:IPR000795" /db_xref="InterPro:IPR005225" /db_xref="InterPro:IPR006847" /db_xref="InterPro:IPR009000" /db_xref="InterPro:IPR015760" /db_xref="InterPro:IPR023115" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR036925" /db_xref="UniProtKB/Swiss-Prot:P9WKK1" /inference="protein motif:PROSITE:PS00017" /experiment="EXISTENCE: identified in proteomics study" BEGIN 1 MAAGKARVHE LAKELGVTSK EVLARLSEQG EFVKSASSTV EAPVARRLRE SFGGSKPAPA 61 KGTAKSPGKG PDKSLDKALD AAIDMAAGNG KATAAPAKAA DSGGAAIVSP TTPAAPEPPT 121 AVPPSPQAPH PGMAPGARPG PVPKPGIRTP RVGNNPFSSA QPADRPIPRP PAPRPGTARP 181 GVPRPGASPG SMPPRPGGAV GGARPPRPGA PRPGGRPGAP GAGRSDAGGG NYRGGGVGAA 241 PGTGFRGRPG GGGGGRPGQR GGAAGAFGRP GGAPRRGRKS KRQKRQEYDS MQAPVVGGVR 301 LPHGNGETIR LARGASLSDF ADKIDANPAA LVQALFNLGE MVTATQSVGD ETLELLGSEM 361 NYNVQVVSPE DEDRELLESF DLSYGEDEGG EEDLQVRPPV VTVMGHVDHG KTRLLDTIRK 421 ANVREAEAGG ITQHIGAYQV AVDLDGSQRL ITFIDTPGHE AFTAMRARGA KATDIAILVV 481 AADDGVMPQT VEAINHAQAA DVPIVVAVNK IDKEGADPAK IRGQLTEYGL VPEEFGGDTM 541 FVDISAKQGT NIEALEEAVL LTADAALDLR ANPDMEAQGV AIEAHLDRGR GPVATVLVQR 601 GTLRVGDSVV AGDAYGRVRR MVDEHGEDVE VALPSRPVQV IGFTSVPGAG DNFLVVDEDR 661 IARQIADRRS ARKRNALAAR SRKRISLEDL DSALKETSQL NLILKGDNAG TVEALEEALM 721 GIQVDDEVVL RVIDRGVGGI TETNVNLASA SDAVIIGFNV RAEGKATELA SREGVEIRYY 781 SVIYQAIDEI EQALRGLLKP IYEENQLGRA EIRALFRSSK VGLIAGCLVT SGVMRRNAKA 841 RLLRDNIVVA ENLSIASLRR EKDDVTEVRD GFECGLTLGY ADIKEGDVIE SYELVQKERA //