LOCUS CCP45572.1 245 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Dihydrodipicolinate reductase
DapB (DHPR) protein.
ACCESSION AL123456-2850
PROTEIN_ID CCP45572.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="dapB"
/locus_tag="Rv2773c"
/note="Rv2773c, (MTV002.38c), len: 245 aa.
DapB,dihydrodipicolinate reductase (see Pavelka et al.,
1997),highly similar to many e.g. P40110|DAPB_CORGL from
Corynebacterium glutamicum (Brevibacterium flavum) (248
aa), FASTA scores: opt: 1030, E(): 1.8e-58, (65.45%
identity in 246 aa overlap); O86836|DAPB_STRCO|SC9A10.03
from Streptomyces coelicolor (250 aa), FASTA scores: opt:
997, E(): 2.3e-56, (61.15% identity in 247 aa overlap);
P42976|DAPB_BACSU from Bacillus subtilis (267 aa), FASTA
scores: opt: 608, E(): 1.7e-31, (45.95% identity in 209 aa
overlap); P46829|DAPB_MYCBO from Mycobacterium bovis (see
Cirillo et al., 1994) (271 aa), FASTA scores: opt:
505,E(): 6.3e-25, (36.2% identity in 246 aa overlap); etc.
Belongs to the dihydrodipicolinate reductase family."
/db_xref="EnsemblGenomes-Gn:Rv2773c"
/db_xref="EnsemblGenomes-Tr:CCP45572"
/db_xref="GOA:P9WP23"
/db_xref="InterPro:IPR000846"
/db_xref="InterPro:IPR022663"
/db_xref="InterPro:IPR022664"
/db_xref="InterPro:IPR023940"
/db_xref="InterPro:IPR036291"
/db_xref="PDB:1C3V"
/db_xref="PDB:1P9L"
/db_xref="PDB:1YL5"
/db_xref="PDB:1YL6"
/db_xref="PDB:1YL7"
/db_xref="PDB:5TEK"
/db_xref="PDB:5TJY"
/db_xref="PDB:5TJZ"
/db_xref="PDB:5UGV"
/db_xref="UniProtKB/Swiss-Prot:P9WP23"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MRVGVLGAKG KVGATMVRAV AAADDLTLSA ELDAGDPLSL LTDGNTEVVI DFTHPDVVMG
61 NLEFLIDNGI HAVVGTTGFT AERFQQVESW LVAKPNTSVL IAPNFAIGAV LSMHFAKQAA
121 RFFDSAEVIE LHHPHKADAP SGTAARTAKL IAEARKGLPP NPDATSTSLP GARGADVDGI
181 PVHAVRLAGL VAHQEVLFGT EGETLTIRHD SLDRTSFVPG VLLAVRRIAE RPGLTVGLEP
241 LLDLH
//