LOCUS       CCP45572.1               245 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Dihydrodipicolinate reductase
            DapB (DHPR) protein.
ACCESSION   AL123456-2850
PROTEIN_ID  CCP45572.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="dapB"
                     /locus_tag="Rv2773c"
                     /note="Rv2773c, (MTV002.38c), len: 245 aa.
                     DapB,dihydrodipicolinate reductase (see Pavelka et al.,
                     1997),highly similar to many e.g. P40110|DAPB_CORGL from
                     Corynebacterium glutamicum (Brevibacterium flavum) (248
                     aa), FASTA scores: opt: 1030, E(): 1.8e-58, (65.45%
                     identity in 246 aa overlap); O86836|DAPB_STRCO|SC9A10.03
                     from Streptomyces coelicolor (250 aa), FASTA scores: opt:
                     997, E(): 2.3e-56, (61.15% identity in 247 aa overlap);
                     P42976|DAPB_BACSU from Bacillus subtilis (267 aa), FASTA
                     scores: opt: 608, E(): 1.7e-31, (45.95% identity in 209 aa
                     overlap); P46829|DAPB_MYCBO from Mycobacterium bovis (see
                     Cirillo et al., 1994) (271 aa), FASTA scores: opt:
                     505,E(): 6.3e-25, (36.2% identity in 246 aa overlap); etc.
                     Belongs to the dihydrodipicolinate reductase family."
                     /db_xref="EnsemblGenomes-Gn:Rv2773c"
                     /db_xref="EnsemblGenomes-Tr:CCP45572"
                     /db_xref="GOA:P9WP23"
                     /db_xref="InterPro:IPR000846"
                     /db_xref="InterPro:IPR022663"
                     /db_xref="InterPro:IPR022664"
                     /db_xref="InterPro:IPR023940"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PDB:1C3V"
                     /db_xref="PDB:1P9L"
                     /db_xref="PDB:1YL5"
                     /db_xref="PDB:1YL6"
                     /db_xref="PDB:1YL7"
                     /db_xref="PDB:5TEK"
                     /db_xref="PDB:5TJY"
                     /db_xref="PDB:5TJZ"
                     /db_xref="PDB:5UGV"
                     /db_xref="UniProtKB/Swiss-Prot:P9WP23"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MRVGVLGAKG KVGATMVRAV AAADDLTLSA ELDAGDPLSL LTDGNTEVVI DFTHPDVVMG
       61 NLEFLIDNGI HAVVGTTGFT AERFQQVESW LVAKPNTSVL IAPNFAIGAV LSMHFAKQAA
      121 RFFDSAEVIE LHHPHKADAP SGTAARTAKL IAEARKGLPP NPDATSTSLP GARGADVDGI
      181 PVHAVRLAGL VAHQEVLFGT EGETLTIRHD SLDRTSFVPG VLLAVRRIAE RPGLTVGLEP
      241 LLDLH
//