LOCUS CCP44734.1 271 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Conserved hypothetical
integral membrane protein YrbE3B protein.
ACCESSION AL123456-2012
PROTEIN_ID CCP44734.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="yrbE3B"
/locus_tag="Rv1965"
/note="Rv1965, (MTV051.03), len: 271 aa.
YrbE4B,hypothetical unknown integral membrane protein,
part of mce3 operon and member of YrbE family (see
citations below), highly similar to Mycobacterium
tuberculosis proteins O07413|Rv0168|MTCI28.08|yrbE1B (289
aa), FASTA scores: opt: 937, E(): 0, (54.3% identity in
254 aa overlap); O07790|Rv0588|MTCY19H5.34|yrbE2B (295
aa); etc. Also highly similar to conserved hypothetical
integral membrane proteins of the yrbEB type, e.g.
AAD24545.1|AF116213|YrbE1B from Mycobacterium leprae (106
aa); P45392|YRBE_ECOLI hypothetical 27.9 kDa protein from
Escherichia coli (260 aa), FASTA scores: opt: 218, E():
1.2e-07, (24.1% identity in 245 aa overlap); etc. The
transcription of this CDS seems negatively regulated by
the product of Rv1963c|mce3R (see Santangelo et al.,
2002)."
/db_xref="EnsemblGenomes-Gn:Rv1965"
/db_xref="EnsemblGenomes-Tr:CCP44734"
/db_xref="GOA:O53966"
/db_xref="InterPro:IPR030802"
/db_xref="UniProtKB/TrEMBL:O53966"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MTAAKALVSE WNRMGSQMRF FVGTLAGIPD ALMHYRGELL RVIAQMGLGT GVLAVIGGTV
61 AIVGFLAMTT GAIVAVQGYN QFASVGVEAL TGFASAFFNT REIQPGTVMV ALAATVGAGT
121 TAALGAMRIN EEIDALEVIG IRSISYLAST RVLAGVVVAV PLFCVGLMTA YLAARVGTTA
181 IYGQGSGVYD HYFNTFLRPT DVLWSSVEVV VVALMIMLVC TYYGYAAHGG PAGVGEAVGR
241 AVRASMVVAS IAILVMTLAI YGQSPNFHLA T
//