LOCUS       CCP44734.1               271 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Conserved hypothetical
            integral membrane protein YrbE3B protein.
ACCESSION   AL123456-2012
PROTEIN_ID  CCP44734.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="yrbE3B"
                     /locus_tag="Rv1965"
                     /note="Rv1965, (MTV051.03), len: 271 aa.
                     YrbE4B,hypothetical unknown integral membrane protein,
                     part of mce3 operon and member of YrbE family (see
                     citations below), highly similar to Mycobacterium
                     tuberculosis proteins O07413|Rv0168|MTCI28.08|yrbE1B (289
                     aa), FASTA scores: opt: 937, E(): 0, (54.3% identity in
                     254 aa overlap); O07790|Rv0588|MTCY19H5.34|yrbE2B (295
                     aa); etc. Also highly similar to conserved hypothetical
                     integral membrane proteins of the yrbEB type, e.g.
                     AAD24545.1|AF116213|YrbE1B from Mycobacterium leprae (106
                     aa); P45392|YRBE_ECOLI hypothetical 27.9 kDa protein from
                     Escherichia coli (260 aa), FASTA scores: opt: 218, E():
                     1.2e-07, (24.1% identity in 245 aa overlap); etc. The
                     transcription of this CDS seems negatively regulated by
                     the product of Rv1963c|mce3R (see Santangelo et al.,
                     2002)."
                     /db_xref="EnsemblGenomes-Gn:Rv1965"
                     /db_xref="EnsemblGenomes-Tr:CCP44734"
                     /db_xref="GOA:O53966"
                     /db_xref="InterPro:IPR030802"
                     /db_xref="UniProtKB/TrEMBL:O53966"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MTAAKALVSE WNRMGSQMRF FVGTLAGIPD ALMHYRGELL RVIAQMGLGT GVLAVIGGTV
       61 AIVGFLAMTT GAIVAVQGYN QFASVGVEAL TGFASAFFNT REIQPGTVMV ALAATVGAGT
      121 TAALGAMRIN EEIDALEVIG IRSISYLAST RVLAGVVVAV PLFCVGLMTA YLAARVGTTA
      181 IYGQGSGVYD HYFNTFLRPT DVLWSSVEVV VVALMIMLVC TYYGYAAHGG PAGVGEAVGR
      241 AVRASMVVAS IAILVMTLAI YGQSPNFHLA T
//