LOCUS CCP44648.1 277 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable short-chain
type dehydrogenase/reductase protein.
ACCESSION AL123456-1926
PROTEIN_ID CCP44648.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/locus_tag="Rv1882c"
/note="Rv1882c, (MTCY180.36), len: 277 aa. Probable
short-chain dehydrogenase/reductase, similar to various
dehydrogenases/reductases, generally belonging to SDR
family, e.g. NP_250789.1|NC_002516 probable short-chain
dehydrogenase from Pseudomonas aeruginosa (251 aa);
NP_421760.1|NC_002696 short chain dehydrogenase family
protein from Caulobacter crescentus (270 aa);
NP_107167.1|NC_002678 oxidoreductase (short chain
dehydrogenase/reductase family) from Mesorhizobium loti
(253 aa); P50197|LINC_PSEPA
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase
from Pseudomonas paucimobilis (Sphingomonas paucimobilis)
(250 aa), FASTA scores: opt: 301, E(): 2.3e-12, (30.0%
identity in 223 aa overlap); etc. Also similar to proteins
from Mycobacterium tuberculosis e.g. Rv3057c, Rv1245, etc.
Contains possible helix-turn-helix motif at aa 246-267
(+4.32 SD). Contains PS00061 Short-chain alcohol
dehydrogenase family signature. Belongs to the short-chain
dehydrogenases/reductases (SDR) family."
/db_xref="EnsemblGenomes-Gn:Rv1882c"
/db_xref="EnsemblGenomes-Tr:CCP44648"
/db_xref="GOA:O07749"
/db_xref="InterPro:IPR002347"
/db_xref="InterPro:IPR020904"
/db_xref="InterPro:IPR036291"
/db_xref="UniProtKB/TrEMBL:O07749"
/inference="protein motif:PROSITE:PS00061"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MKAIFITGAG SGMGREGATL FHANGWRVGA IDRNEDGLAA LRVQLGAERL WARAVDVTDK
61 AALEGALADF CAGNVGGGLD MMWNNAGIGE GGWFEDVPYE AAVRVVDVNF KAVLTGAYAA
121 LPYLKKAPGS LMFSTSSSSG TYGMPRIAVY SATKHAVKGL TEALSVEWQR HGVRVADVLP
181 GLIDTAILTS TRQHSDEGPY TISAEQIRAA APKKGMFRLM PSSSVAEAAW RAYQHPTRLH
241 WYVPRSIRWI DRLKGVSPEF VRRHIAKSLA TLEPKRK
//