LOCUS       CCP44648.1               277 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable short-chain
            type dehydrogenase/reductase protein.
ACCESSION   AL123456-1926
PROTEIN_ID  CCP44648.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /locus_tag="Rv1882c"
                     /note="Rv1882c, (MTCY180.36), len: 277 aa. Probable
                     short-chain dehydrogenase/reductase, similar to various
                     dehydrogenases/reductases, generally belonging to SDR
                     family, e.g. NP_250789.1|NC_002516 probable short-chain
                     dehydrogenase from Pseudomonas aeruginosa (251 aa);
                     NP_421760.1|NC_002696 short chain dehydrogenase family
                     protein from Caulobacter crescentus (270 aa);
                     NP_107167.1|NC_002678 oxidoreductase (short chain
                     dehydrogenase/reductase family) from Mesorhizobium loti
                     (253 aa); P50197|LINC_PSEPA
                     2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase
                     from Pseudomonas paucimobilis (Sphingomonas paucimobilis)
                     (250 aa), FASTA scores: opt: 301, E(): 2.3e-12, (30.0%
                     identity in 223 aa overlap); etc. Also similar to proteins
                     from Mycobacterium tuberculosis e.g. Rv3057c, Rv1245, etc.
                     Contains possible helix-turn-helix motif at aa 246-267
                     (+4.32 SD). Contains PS00061 Short-chain alcohol
                     dehydrogenase family signature. Belongs to the short-chain
                     dehydrogenases/reductases (SDR) family."
                     /db_xref="EnsemblGenomes-Gn:Rv1882c"
                     /db_xref="EnsemblGenomes-Tr:CCP44648"
                     /db_xref="GOA:O07749"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="UniProtKB/TrEMBL:O07749"
                     /inference="protein motif:PROSITE:PS00061"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MKAIFITGAG SGMGREGATL FHANGWRVGA IDRNEDGLAA LRVQLGAERL WARAVDVTDK
       61 AALEGALADF CAGNVGGGLD MMWNNAGIGE GGWFEDVPYE AAVRVVDVNF KAVLTGAYAA
      121 LPYLKKAPGS LMFSTSSSSG TYGMPRIAVY SATKHAVKGL TEALSVEWQR HGVRVADVLP
      181 GLIDTAILTS TRQHSDEGPY TISAEQIRAA APKKGMFRLM PSSSVAEAAW RAYQHPTRLH
      241 WYVPRSIRWI DRLKGVSPEF VRRHIAKSLA TLEPKRK
//