LOCUS       AJF01514.1               265 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena Conserved integral
            membrane protein YrbE1A protein.
ACCESSION   CP007027-170
PROTEIN_ID  AJF01514.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="yrbE1A"
                     /locus_tag="Y980_0167"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0167, (MTCI28.07) YrbE1A, unknown integral
                     membrane protein, part of mce1 operon and member of YrbE
                     family (see citations below), highly similar to
                     Mycobacterium tuberculosis proteins
                     O07791|Rv0587|MTCY19H5.35|yrbE2A (265 aa);
                     O53965|Rv1964|MTV051.02|yrbE3A (265 aa); etc. Also highly
                     similar or similar to conserved hypothetical integral
                     membrane proteins of yrbEA type, e.g.
                     NP_302654.1|NC_002677 conserved membrane protein from
                     Mycobacterium leprae (267 aa); P45030|YRBE_HAEIN|HI1086
                     hypothetical protein from Haemophilus influenzae (261 aa);
                     etc."
                     /transl_table=11
                     /db_xref="InterPro:IPR003453"
                     /db_xref="UniProtKB/TrEMBL:L7N5B8"
BEGIN
        1 MTTSTTLGGY VRDQLQTPLT LVGGFFRMCV LTGKALFRWP FQWREFILQC WFIMRVGFLP
       61 TIMVSIPLTV LLIFTLNILL AQFGAADISG SGAAIGAVTQ LGPLTTVLVV AGAGSTAICA
      121 DLGARTIREE IDAMEVLGID PIHRLVVPRV LASMLVATLL NGLVITVGLV GGFLFGVYLQ
      181 NVSGGAYLAT LTLITGLPEV VIATIKAATF GLIAGLVGCY RGLTVRGGSK GLGTAVNETV
      241 VLCVIALFAV NVILTTIGVR FGTGR
//