LOCUS AJF01514.1 265 aa PRT BCT 20-JUN-2017 DEFINITION Mycobacterium tuberculosis H37RvSiena Conserved integral membrane protein YrbE1A protein. ACCESSION CP007027-170 PROTEIN_ID AJF01514.1 SOURCE Mycobacterium tuberculosis H37RvSiena ORGANISM Mycobacterium tuberculosis H37RvSiena Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 (bases 1 to 4410911) AUTHORS Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G. TITLE Genomic polymorphisms in a Laboratory Isolate of Mycobacterium tuberculosis Reference Strain H37Rv (ATCC27294) JOURNAL New Microbiol. 40 (1), 62-69 (2017) PUBMED 27819398 REFERENCE 2 (bases 1 to 4410911) AUTHORS Guerrini,V., Santoro,F. and Pozzi,G. TITLE Direct Submission JOURNAL Submitted (30-DEC-2013) Medical Biotechnology, University of Siena, viale Bracci, Policlinico Le Scotte, Siena 53100, Italy REFERENCE 3 (bases 1 to 4410911) AUTHORS Guerrini,V., Santoro,F. and Pozzi,G. TITLE Direct Submission JOURNAL Submitted (20-FEB-2015) Medical Biotechnology, University of Siena, viale Bracci, Policlinico Le Scotte, Siena 53100, Italy REMARK Protein update by submitter COMMENT Annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (released 2013). Information about the Pipeline can be found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/ Annotation modified by submitter. ##Assembly-Data-START## Assembly Method :: Ray v. 2.3.1 Coverage :: 300 Sequencing Technology :: Illumina ##Assembly-Data-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Date :: 12/30/2013 09:28:23 Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline Annotation Method :: Best-placed reference protein set; GeneMarkS+ Annotation Software revision :: 2.3 (rev. 422554) Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region Genes :: 4,146 CDS :: 4,050 Pseudo Genes :: 42 CRISPR Arrays :: 2 rRNAs :: 3 (5S, 16S, 23S) tRNAs :: 45 ncRNA :: 6 Frameshifted Genes :: 34 ##Genome-Annotation-Data-END## FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37RvSiena" /mol_type="genomic DNA" /strain="H37RvSiena" /db_xref="taxon:1437856" protein /gene="yrbE1A" /locus_tag="Y980_0167" /experiment="EXISTENCE: identified in proteomics study" /note="Rv0167, (MTCI28.07) YrbE1A, unknown integral membrane protein, part of mce1 operon and member of YrbE family (see citations below), highly similar to Mycobacterium tuberculosis proteins O07791|Rv0587|MTCY19H5.35|yrbE2A (265 aa); O53965|Rv1964|MTV051.02|yrbE3A (265 aa); etc. Also highly similar or similar to conserved hypothetical integral membrane proteins of yrbEA type, e.g. NP_302654.1|NC_002677 conserved membrane protein from Mycobacterium leprae (267 aa); P45030|YRBE_HAEIN|HI1086 hypothetical protein from Haemophilus influenzae (261 aa); etc." /transl_table=11 /db_xref="InterPro:IPR003453" /db_xref="UniProtKB/TrEMBL:L7N5B8" BEGIN 1 MTTSTTLGGY VRDQLQTPLT LVGGFFRMCV LTGKALFRWP FQWREFILQC WFIMRVGFLP 61 TIMVSIPLTV LLIFTLNILL AQFGAADISG SGAAIGAVTQ LGPLTTVLVV AGAGSTAICA 121 DLGARTIREE IDAMEVLGID PIHRLVVPRV LASMLVATLL NGLVITVGLV GGFLFGVYLQ 181 NVSGGAYLAT LTLITGLPEV VIATIKAATF GLIAGLVGCY RGLTVRGGSK GLGTAVNETV 241 VLCVIALFAV NVILTTIGVR FGTGR //