LOCUS AAC50215.1 1629 aa PRT HUM 30-SEP-1995
DEFINITION Homo sapiens Pro-a2(XI) protein.
ACCESSION U32169-3
PROTEIN_ID AAC50215.1
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 28789)
AUTHORS Vuristo,M.M., Pihlajamaa,T., Vandenberg,P., Prockop,D.J. and
Ala-Kokko,L.
TITLE The human COL11A2 gene structure indicates that the gene has not
evolved with the genes for the major fibrillar collagens
JOURNAL J. Biol. Chem. 270 (39), 22873-22881 (1995)
PUBMED 7559422
REFERENCE 2 (sites)
AUTHORS Zhidkova,N.I., Brewton,R.G. and Mayne,R.
TITLE Molecular cloning of PARP (proline/arginine-rich protein) from
human cartilage and subsequent demonstration that PARP is a
fragment of the NH2-terminal domain of the collagen alpha 2(XI)
chain
JOURNAL FEBS Lett. 326 (1-3), 25-28 (1993)
PUBMED 8325374
REFERENCE 3 (sites)
AUTHORS Kimura,T., Cheah,K.S., Chan,S.D., Lui,V.C., Mattei,M.G., van der
Rest,M., Ono,K., Solomon,E., Ninomiya,Y. and Olsen,B.R.
TITLE The human alpha 2(XI) collagen (COL11A2) chain. Molecular cloning
of cDNA and genomic DNA reveals characteristics of a fibrillar
collagen with differences in genomic organization
JOURNAL J. Biol. Chem. 264 (23), 13910-13916 (1989)
PUBMED 2760050
REFERENCE 4 (bases 1 to 28789)
AUTHORS Tsumaki,N. and Kimura,T.
TITLE Differential expression of an acidic domain in the amino-terminal
propeptide of mouse pro-alpha 2(XI) collagen by complex alternative
splicing
JOURNAL J. Biol. Chem. 270 (5), 2372-2378 (1995)
PUBMED 7836472
REFERENCE 5 (bases 1 to 28789)
AUTHORS Zhidkova,N.I., Justice,S.K. and Mayne,R.
TITLE Alternative mRNA processing occurs in the variable region of the
pro-alpha 1(XI) and pro-alpha 2(XI) collagen chains
JOURNAL J. Biol. Chem. 270 (16), 9486-9493 (1995)
PUBMED 7721876
REFERENCE 6 (bases 1 to 28789)
AUTHORS Vuoristo,M.M.
TITLE Direct Submission
JOURNAL Submitted (24-JUL-1995) Mirka M. Vuoristo, Dept. of Biochemistry
and Molecular Biology, Thomas Jefferson University, 233 South 10th
Street, Philadelphia, PA 19107, USA
FEATURES Qualifiers
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6p212"
protein /gene="COL11A2"
/standard_name="pro-a2 chain of collagen type XI"
/experiment="experimental evidence, no additional details
recorded"
/note="lacks alternative exons 6, 7 and 8"
/citation=[5]
intron_pos 28:1 (1/62)
intron_pos 78:1 (2/62)
intron_pos 148:2 (3/62)
intron_pos 203:0 (4/62)
intron_pos 267:0 (5/62)
intron_pos 287:0 (6/62)
intron_pos 301:0 (7/62)
intron_pos 322:0 (8/62)
intron_pos 347:0 (9/62)
intron_pos 376:0 (10/62)
intron_pos 395:0 (11/62)
intron_pos 413:0 (12/62)
intron_pos 431:0 (13/62)
intron_pos 449:0 (14/62)
intron_pos 467:0 (15/62)
intron_pos 485:0 (16/62)
intron_pos 500:0 (17/62)
intron_pos 518:0 (18/62)
intron_pos 533:0 (19/62)
intron_pos 551:0 (20/62)
intron_pos 566:0 (21/62)
intron_pos 584:0 (22/62)
intron_pos 599:0 (23/62)
intron_pos 617:0 (24/62)
intron_pos 632:0 (25/62)
intron_pos 650:0 (26/62)
intron_pos 686:0 (27/62)
intron_pos 704:0 (28/62)
intron_pos 722:0 (29/62)
intron_pos 737:0 (30/62)
intron_pos 755:0 (31/62)
intron_pos 770:0 (32/62)
intron_pos 788:0 (33/62)
intron_pos 806:0 (34/62)
intron_pos 824:0 (35/62)
intron_pos 860:0 (36/62)
intron_pos 890:0 (37/62)
intron_pos 908:0 (38/62)
intron_pos 944:0 (39/62)
intron_pos 980:0 (40/62)
intron_pos 998:0 (41/62)
intron_pos 1016:0 (42/62)
intron_pos 1052:0 (43/62)
intron_pos 1070:0 (44/62)
intron_pos 1088:0 (45/62)
intron_pos 1106:0 (46/62)
intron_pos 1124:0 (47/62)
intron_pos 1160:0 (48/62)
intron_pos 1178:0 (49/62)
intron_pos 1196:0 (50/62)
intron_pos 1214:0 (51/62)
intron_pos 1232:0 (52/62)
intron_pos 1268:0 (53/62)
intron_pos 1286:0 (54/62)
intron_pos 1304:0 (55/62)
intron_pos 1340:0 (56/62)
intron_pos 1358:0 (57/62)
intron_pos 1370:0 (58/62)
intron_pos 1388:0 (59/62)
intron_pos 1477:1 (60/62)
intron_pos 1515:0 (61/62)
intron_pos 1584:0 (62/62)
BEGIN
1 MERCSXGHRL LLLLPLVLGL SAAPGWAGAP PVDVLRALRF PSLPDGVRRA KGICPADVAY
61 RVARPAQLSA PTRQLFPGGF PKDFSLLTVV RTRPGLQAPL LTLYSAQGVR QLGLELGRPV
121 RFLYEDQTGR PQPPSQPVFR GLSLADGKWH RVAVAVKGQS VTLIVDCKKR VTRPLPRSAR
181 PVLDTHGVII FGARILDEEV FEGDVQELAI VPGVQAAYES CEQKELECEG GQRERPQNQQ
241 PHRAQRSPQQ QPSRLHRPQN QEPQSQAAHG PRGLKGEKGE PAVLEPGMLV EGPPGPEGPA
301 GLIGPPGIQG NPGPVGDPGE RGPPGRAGLP GSDGAPGPPG TSLMLPFRFG SGGGDKGPVV
361 AAQEAQAQAI LQQARLALRG PPGPMGYTGR PGPLGQPGSP GLKGESGDLG PQGPRGPQGL
421 TGSLGKAGRR GRAGADGARG MPGDPGVKGD RGFDGLPGLP GEKGHRGDTG AQGLPGPPGE
481 DGERGDDGEI GPRGLPGESG PRGLLGPKGP PGIPGPPGVR GMDGPQGPKG SLGPQGEPGP
541 PGQQGTPGTQ GLPGPQGAIG PHGEKGPQGK PGLPGMPGSD GPPGHPGKEG PPGTKGNQGP
601 SGPQGPLGYP GPRGVKGVDG IRGLKGHKGE KGEDGFPGFK GDIGVKGDRG EVGVPGSRGE
661 DGPEGPKGRT GPTGDPGPPG LMGEKGKLGV PGLPGYPGRQ GPKGSLGFPG FPGASGEKGA
721 RGLSGKSGPR GERGPTGPRG QRGPRGATGK SGAKGTSGGD GPHGPPGERG LPGPQGPNGF
781 PGPKGPLGPP GKDGLPGHPG QRGEVGFQGK TGPPGPPGVV GPQGAAGETG PMGERGHPGP
841 PGPPGEQGLP GTAGKEGTKG DPGPPGAPGK DGPAGLRGFP GERGLPGTAG GPGLKGNEGP
901 SGPPGPAGSP GERGAAGSGG PIGRQGRPGP QGPPGAAGEK GVPGEKGPIG PTGRDGVQGP
961 VGLPGPAGPP GVAGEDGDKG EVGDPGQKGT KGNKGEHGPP GPPGPIGPVG QPGAAGADGE
1021 PGARGPQGHF GAKGDEGTRG FNGPPGPIGL QGLPGPSGEK GETGDVGPMG PPGPPGPRGP
1081 AGPNGADGPQ GPPGGVGNLG PPGEKGEPGE SGSPGIQGEP GVKGPRGERG EKGESGQPGE
1141 PGPPGAKGPQ GDDGPKGNPG PVGFPGDPGP PGEGGPRGQD GAKGDRGEDG EPGQPGSPGP
1201 TGENGPPGPL GKRGPAGSPG SEGRQGGKGA KGDPGAIGAP GKTGPVGPAG PAGKPGPDGL
1261 RGLPGSVGQQ GRPGATGQAG PPGPVGPPGL PGLRGDAGAK GEKGHPGLIG LIGPPGEQGE
1321 KGDRGLPGPQ GSPGQKGEMG IPGASGPIGP GGPPGLPGPA GPKGAKGATG PGGPKGEKGV
1381 QGPPGHPGPP GEVIQPLPIQ MPKKTRRSVD GSRLMQEDEA IPTGGAPGSP GGLEEIFGSL
1441 DSLREEIEQM RRPTGTQDSP ARTCQDLKLC HPELPDGEYW VDPNQGCARD AFRVFCNFTA
1501 GGETCVTPRD DVTQFSYVDS EGSPVGVVQL TFLRLLSVSA HQDVSYPCSG AARDGPLRLR
1561 GANEDELSPE TSPYVKEFRD GCQTQQGRTV LEVRTPVLEQ LPVLDASFSD LGAPPRRGGV
1621 LLGPVCFMG
//