LOCUS AAA86473.1 323 aa PRT HUM 10-JUN-2016
DEFINITION Homo sapiens CTLA-4 counter-receptor B7.2 protein.
ACCESSION AH003329-1
PROTEIN_ID AAA86473.1
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Azuma,M., Ito,D., Yagita,H., Okumura,K., Phillips,J.H., Lanier,L.L.
and Somoza,C.
TITLE B70 antigen is a second ligand for CTLA-4 and CD28
JOURNAL Nature 366 (6450), 76-79 (1993)
PUBMED 7694153
REFERENCE 2 (bases 173 to 292; 579 to 1050; 1151 to 1634; 1735 to 2475; 2576
to 3312; 3413 to 3983; 4084 to 4741; 4842 to 5471)
AUTHORS Freeman,G.J., Gribben,J.G., Boussiotis,V.A., Ng,J.W., Restivo,V.A.
Jr., Lombard,L.A., Gray,G.S. and Nadler,L.M.
TITLE Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human
T cell proliferation
JOURNAL Science 262 (5135), 909-911 (1993)
PUBMED 7694363
REFERENCE 3 (bases 1 to 5471)
AUTHORS Jellis,C.L., Wang,S.S., Rennert,P., Borriello,F., Sharpe,A.H.,
Green,N.R. and Gray,G.S.
TITLE Genomic organization of the gene coding for the costimulatory human
B-lymphocyte antigen B7-2 (CD86)
JOURNAL Immunogenetics 42 (2), 85-89 (1995)
PUBMED 7541777
REFERENCE 4 (bases 1 to 5471)
AUTHORS Jellis,C.L.
TITLE Direct Submission
JOURNAL Submitted (29-NOV-1994) Cindy L. Jellis, Molecular Biology,
Repligen Corporation, One Kendall Square, Building 700, Cambridge,
MA 02139, USA
COMMENT On or before Jun 10, 2016 this sequence version replaced U17715.1,
U17716.1, U17717.1, U17718.1, U17719.1, U17720.1, U17721.1,
U17722.1, AH003329.1.
FEATURES Qualifiers
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/sex="male"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company Human
foreskin Fibroblast P1 Library no.1"
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/clone="DMPC-HFF no.1-1390-A1 hB7.2 genomic DNA (exon 1)"
/sex="male"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company Human
foreskin Fibroblast P1 Library no.1"
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/clone="DMPC-HFF no.1-1390-A1"
/sex="male"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company Human
foreskin Fibroblast P1 Library no.1"
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/clone="DMPC-HFF no.1-1307-7C Human B7.2 genomic DNA"
/sex="male"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company Human
foreskin Fibroblast P1 Library no.1"
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/clone="DMPC-HFF no.1-1307-7C"
/sex="male"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company Human
foreskin Fibroblast P1 Library no.1"
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/clone="DMPC-HFF no.1-1307-7C"
/sex="male"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company Human
foreskin Fibroblast P1 Library no.1"
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/clone="DMPC-HFF no.1-1307-7C"
/sex="male"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company Human
foreskin Fibroblast P1 Library no.1"
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/clone="DMPC-HFF no.1-1307-7C"
/sex="male"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company Human
foreskin Fibroblast P1 Library no.1"
source /organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/clone="DMPC-HFF no.1"
/sex="male"
/cell_type="fibroblast"
/tissue_type="foreskin"
/clone_lib="Du Pont Merck Pharmaceutical Company Human
foreskin Fibroblast P1 Library no.1"
protein /gene="B7.2"
intron_pos 16:1 (1/5)
intron_pos 128:1 (2/5)
intron_pos 229:1 (3/5)
intron_pos 277:1 (4/5)
intron_pos 292:2 (5/5)
BEGIN
1 MGLSNILFVM AFLLSGAAPL EIQAYFNETA DLPCQFANSQ NQSLSELVVF WQDQENLVLN
61 EVYLGKEKFD SVHSKYMGRT SFDSDSWTLR LHNLQIKDKG LYQCIIHHKK PTGMIRIHQM
121 NSELSVLANF SQPEIVPISN ITENVYINLT CSSIHGYPEP KKMSVLLRTK NSTIEYDGIM
181 QKSQDNVTEL YDVSISLSVS FPDVTSNMTI FCILETDKTR LLSSPFSIEL EDPQPPPDHI
241 PWITAVLPTV IICVMVFCLI LWKWKKKKRP RNSYKCGTNT MEREESEQTK KREKIHIPER
301 SDEAQRVFKS SKTSSCDKSD TCF
//