LOCUS       AAA86473.1               323 aa    PRT              HUM 10-JUN-2016
DEFINITION  Homo sapiens CTLA-4 counter-receptor B7.2 protein.
ACCESSION   AH003329-1
PROTEIN_ID  AAA86473.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (sites)
  AUTHORS   Azuma,M., Ito,D., Yagita,H., Okumura,K., Phillips,J.H., Lanier,L.L.
            and Somoza,C.
  TITLE     B70 antigen is a second ligand for CTLA-4 and CD28
  JOURNAL   Nature 366 (6450), 76-79 (1993)
   PUBMED   7694153
REFERENCE   2  (bases 173 to 292; 579 to 1050; 1151 to 1634; 1735 to 2475; 2576
            to 3312; 3413 to 3983; 4084 to 4741; 4842 to 5471)
  AUTHORS   Freeman,G.J., Gribben,J.G., Boussiotis,V.A., Ng,J.W., Restivo,V.A.
            Jr., Lombard,L.A., Gray,G.S. and Nadler,L.M.
  TITLE     Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human
            T cell proliferation
  JOURNAL   Science 262 (5135), 909-911 (1993)
   PUBMED   7694363
REFERENCE   3  (bases 1 to 5471)
  AUTHORS   Jellis,C.L., Wang,S.S., Rennert,P., Borriello,F., Sharpe,A.H.,
            Green,N.R. and Gray,G.S.
  TITLE     Genomic organization of the gene coding for the costimulatory human
            B-lymphocyte antigen B7-2 (CD86)
  JOURNAL   Immunogenetics 42 (2), 85-89 (1995)
   PUBMED   7541777
REFERENCE   4  (bases 1 to 5471)
  AUTHORS   Jellis,C.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-1994) Cindy L. Jellis, Molecular Biology,
            Repligen Corporation, One Kendall Square, Building 700, Cambridge,
            MA 02139, USA
COMMENT     On or before Jun 10, 2016 this sequence version replaced U17715.1,
            U17716.1, U17717.1, U17718.1, U17719.1, U17720.1, U17721.1,
            U17722.1, AH003329.1.
FEATURES             Qualifiers
     source          /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /sex="male"
                     /cell_type="fibroblast"
                     /tissue_type="foreskin"
                     /clone_lib="Du Pont Merck Pharmaceutical Company Human
                     foreskin Fibroblast P1 Library no.1"
     source          /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /clone="DMPC-HFF no.1-1390-A1 hB7.2 genomic DNA (exon 1)"
                     /sex="male"
                     /cell_type="fibroblast"
                     /tissue_type="foreskin"
                     /clone_lib="Du Pont Merck Pharmaceutical Company Human
                     foreskin Fibroblast P1 Library no.1"
     source          /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /clone="DMPC-HFF no.1-1390-A1"
                     /sex="male"
                     /cell_type="fibroblast"
                     /tissue_type="foreskin"
                     /clone_lib="Du Pont Merck Pharmaceutical Company Human
                     foreskin Fibroblast P1 Library no.1"
     source          /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /clone="DMPC-HFF no.1-1307-7C Human B7.2 genomic DNA"
                     /sex="male"
                     /cell_type="fibroblast"
                     /tissue_type="foreskin"
                     /clone_lib="Du Pont Merck Pharmaceutical Company Human
                     foreskin Fibroblast P1 Library no.1"
     source          /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /clone="DMPC-HFF no.1-1307-7C"
                     /sex="male"
                     /cell_type="fibroblast"
                     /tissue_type="foreskin"
                     /clone_lib="Du Pont Merck Pharmaceutical Company Human
                     foreskin Fibroblast P1 Library no.1"
     source          /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /clone="DMPC-HFF no.1-1307-7C"
                     /sex="male"
                     /cell_type="fibroblast"
                     /tissue_type="foreskin"
                     /clone_lib="Du Pont Merck Pharmaceutical Company Human
                     foreskin Fibroblast P1 Library no.1"
     source          /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /clone="DMPC-HFF no.1-1307-7C"
                     /sex="male"
                     /cell_type="fibroblast"
                     /tissue_type="foreskin"
                     /clone_lib="Du Pont Merck Pharmaceutical Company Human
                     foreskin Fibroblast P1 Library no.1"
     source          /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /clone="DMPC-HFF no.1-1307-7C"
                     /sex="male"
                     /cell_type="fibroblast"
                     /tissue_type="foreskin"
                     /clone_lib="Du Pont Merck Pharmaceutical Company Human
                     foreskin Fibroblast P1 Library no.1"
     source          /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /clone="DMPC-HFF no.1"
                     /sex="male"
                     /cell_type="fibroblast"
                     /tissue_type="foreskin"
                     /clone_lib="Du Pont Merck Pharmaceutical Company Human
                     foreskin Fibroblast P1 Library no.1"
     protein         /gene="B7.2"
     intron_pos      16:1 (1/5)
     intron_pos      128:1 (2/5)
     intron_pos      229:1 (3/5)
     intron_pos      277:1 (4/5)
     intron_pos      292:2 (5/5)
BEGIN
        1 MGLSNILFVM AFLLSGAAPL EIQAYFNETA DLPCQFANSQ NQSLSELVVF WQDQENLVLN
       61 EVYLGKEKFD SVHSKYMGRT SFDSDSWTLR LHNLQIKDKG LYQCIIHHKK PTGMIRIHQM
      121 NSELSVLANF SQPEIVPISN ITENVYINLT CSSIHGYPEP KKMSVLLRTK NSTIEYDGIM
      181 QKSQDNVTEL YDVSISLSVS FPDVTSNMTI FCILETDKTR LLSSPFSIEL EDPQPPPDHI
      241 PWITAVLPTV IICVMVFCLI LWKWKKKKRP RNSYKCGTNT MEREESEQTK KREKIHIPER
      301 SDEAQRVFKS SKTSSCDKSD TCF
//