LOCUS AAA60225.1 2314 aa PRT HUM 08-JAN-1995
DEFINITION Homo sapiens protein tyrosine phosphatase zeta-polypeptide protein.
ACCESSION M93426-1
PROTEIN_ID AAA60225.1
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7941)
AUTHORS Krueger,N.X. and Saito,H.
TITLE A human transmembrane protein-tyrosine-phosphatase, PTP zeta, is
expressed in brain and has an N-terminal receptor domain homologous
to carbonic anhydrases
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 89 (16), 7417-7421 (1992)
PUBMED 1323835
COMMENT Original source text: Homo sapiens (tissue library: lambda gt10 and
gt11) fetus brain cDNA to mRNA.
FEATURES Qualifiers
source /db_xref="H-InvDB:HIT000196852"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Unassigned"
/tissue_type="brain"
/dev_stage="fetus"
/tissue_lib="lambda gt10 and gt11"
protein /gene="PTPRZ"
/note="carbonic anhydrase-like domain"
/db_xref="GDB:G00-127-353"
BEGIN
1 MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK
61 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV
121 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS
181 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC
241 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY
301 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRVVYD TMIEKFAVLY QQLDGEDQTK
361 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE
421 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN
481 RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND
541 GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS
601 ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI
661 TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP
721 TEVTPHAFTP SSRQQDLVST VNVVYSQTTQ PVYNGETPLQ PSYSSEVFPL VTPLLLDNQI
781 LNTTPAASSS DSALHATPVF PSVDVSFESI LSSYDGAPLL PFSSASFSSE LFRHLHTVSQ
841 ILPQVTSATE SDKVPLHASL PVAGGDLLLE PSLAQYSDVL STTHAASETL EFGSESGVLY
901 KTLMFSQVEP PSSDAMMHAR SSGPEPSYAL SDNEGSQHIF TVSYSSAIPV HDSVGVTYQG
961 SLFSGPSHIP IPKSSLITPT ASLLQPTHAL SGDGEWSGAS SDSEFLLPDT DGLTALNISS
1021 PVSVAEFTYT TSVFGDDNKA LSKSEIIYGN ETELQIPSFN EMVYPSESTV MPNMYDNVNK
1081 LNASLQETSV SISSTKGMFP GSLAHTTTKV FDHEISQVPE NNFSVQPTHT VSQASGDTSL
1141 KPVLSANSEP ASSDPASSEM LSPSTQLLFY ETSASFSTEV LLQPSFQASD VDTLLKTVLP
1201 AVPSDPILVE TPKVDKISST MLHLIVSNSA SSENMLHSTS VPVFDVSPTS HMHSASLQGL
1261 TISYASEKYE PVLLKSESSH QVVPSLYSND ELFQTANLEI NQAHPPKGRH VFATPVLSID
1321 EPLNTLINKL IHSDEILTST KSSVTGKVFA GIPTVASDTF VSTDHSVPIG NGHVAITAVS
1381 PHRDGSVTST KLLFPSKATS ELSHSAKSDA GLVGGGEDGD TDDDGDDDDD RDSDGLSIHK
1441 CMSCSSYRES QEKVMNDSDT HENSLMDQNN PISYSLSENS EEDNRVTSVS SDSQTGMDRS
1501 PGKSPSANGL SQKHNDGKEE NDIQTGSALL PLSPESKAWA VLTSDEESGS GQGTSDSLNE
1561 NETSTDFSFA DTNEKDADGI LAAGDSEITP GFPQSPTSSV TSENSEVFHV SEAEASNSSH
1621 ESRIGLAEGL ESEKKAVIPL VIVSALTFIC LVVLVGILIY WRKCFQTAHF YLEDSTSPRV
1681 ISTPPTPIFP ISDDVGAIPI KHFPKHVADL HASSGFTEEF ETLKEFYQEV QSCTVDLGIT
1741 ADSSNHPDNK HKNRYINIVA YDHSRVKLAQ LAEKDGKLTD YINANYVDGY NRPKAYIAAQ
1801 GPLKSTAEDF WRMIWEHNVE VIVMITNLVE KGRRKCDQYW PADGSEEYGN FLVTQKSVQV
1861 LAYYTVRNFT LRNTKIKKGS QKGRPSGRVV TQYHYTQWPD MGVPEYSLPV LTFVRKAAYA
1921 KRHAVGPVVV HCSAGVGRTG TYIVLDSMLQ QIQHEGTVNI FGFLKHIRSQ RNYLVQTEEQ
1981 YVFIHDTLVE AILSKETEVL DSHIHAYVNA LLIPGPAGKT KLEKQFQLLS QSNIQQSDYS
2041 AALKQCNREK NRTSSIIPVE RSRVGISSLS GEGTDYINAS YIMGYYQSNE FIITQHPLLH
2101 TIKDFWRMIW DHNAQLVVMI PDGQNMAEDE FVYWPNKDEP INCESFKVTL MAEEHKCLSN
2161 EEKLIIQDFI LEATQDDYVL EVRHFQCPKW PNPDSPISKT FELISVIKEE AANRDGPMIV
2221 HDEHGGVTAG TFCALTTLMH QLEKENSVDV YQVAKMINLM RPGVFADIEQ YQFLYKVILS
2281 LVSTRQEENP STSLDSNGAA LPDGNIAESL ESLV
//