LOCUS       AAA60225.1              2314 aa    PRT              HUM 08-JAN-1995
DEFINITION  Homo sapiens protein tyrosine phosphatase zeta-polypeptide protein.
ACCESSION   M93426-1
PROTEIN_ID  AAA60225.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7941)
  AUTHORS   Krueger,N.X. and Saito,H.
  TITLE     A human transmembrane protein-tyrosine-phosphatase, PTP zeta, is
            expressed in brain and has an N-terminal receptor domain homologous
            to carbonic anhydrases
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89 (16), 7417-7421 (1992)
   PUBMED   1323835
COMMENT     Original source text: Homo sapiens (tissue library: lambda gt10 and
            gt11) fetus brain cDNA to mRNA.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000196852"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /map="Unassigned"
                     /tissue_type="brain"
                     /dev_stage="fetus"
                     /tissue_lib="lambda gt10 and gt11"
     protein         /gene="PTPRZ"
                     /note="carbonic anhydrase-like domain"
                     /db_xref="GDB:G00-127-353"
BEGIN
        1 MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK
       61 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV
      121 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS
      181 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC
      241 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY
      301 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRVVYD TMIEKFAVLY QQLDGEDQTK
      361 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE
      421 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN
      481 RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND
      541 GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS
      601 ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI
      661 TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP
      721 TEVTPHAFTP SSRQQDLVST VNVVYSQTTQ PVYNGETPLQ PSYSSEVFPL VTPLLLDNQI
      781 LNTTPAASSS DSALHATPVF PSVDVSFESI LSSYDGAPLL PFSSASFSSE LFRHLHTVSQ
      841 ILPQVTSATE SDKVPLHASL PVAGGDLLLE PSLAQYSDVL STTHAASETL EFGSESGVLY
      901 KTLMFSQVEP PSSDAMMHAR SSGPEPSYAL SDNEGSQHIF TVSYSSAIPV HDSVGVTYQG
      961 SLFSGPSHIP IPKSSLITPT ASLLQPTHAL SGDGEWSGAS SDSEFLLPDT DGLTALNISS
     1021 PVSVAEFTYT TSVFGDDNKA LSKSEIIYGN ETELQIPSFN EMVYPSESTV MPNMYDNVNK
     1081 LNASLQETSV SISSTKGMFP GSLAHTTTKV FDHEISQVPE NNFSVQPTHT VSQASGDTSL
     1141 KPVLSANSEP ASSDPASSEM LSPSTQLLFY ETSASFSTEV LLQPSFQASD VDTLLKTVLP
     1201 AVPSDPILVE TPKVDKISST MLHLIVSNSA SSENMLHSTS VPVFDVSPTS HMHSASLQGL
     1261 TISYASEKYE PVLLKSESSH QVVPSLYSND ELFQTANLEI NQAHPPKGRH VFATPVLSID
     1321 EPLNTLINKL IHSDEILTST KSSVTGKVFA GIPTVASDTF VSTDHSVPIG NGHVAITAVS
     1381 PHRDGSVTST KLLFPSKATS ELSHSAKSDA GLVGGGEDGD TDDDGDDDDD RDSDGLSIHK
     1441 CMSCSSYRES QEKVMNDSDT HENSLMDQNN PISYSLSENS EEDNRVTSVS SDSQTGMDRS
     1501 PGKSPSANGL SQKHNDGKEE NDIQTGSALL PLSPESKAWA VLTSDEESGS GQGTSDSLNE
     1561 NETSTDFSFA DTNEKDADGI LAAGDSEITP GFPQSPTSSV TSENSEVFHV SEAEASNSSH
     1621 ESRIGLAEGL ESEKKAVIPL VIVSALTFIC LVVLVGILIY WRKCFQTAHF YLEDSTSPRV
     1681 ISTPPTPIFP ISDDVGAIPI KHFPKHVADL HASSGFTEEF ETLKEFYQEV QSCTVDLGIT
     1741 ADSSNHPDNK HKNRYINIVA YDHSRVKLAQ LAEKDGKLTD YINANYVDGY NRPKAYIAAQ
     1801 GPLKSTAEDF WRMIWEHNVE VIVMITNLVE KGRRKCDQYW PADGSEEYGN FLVTQKSVQV
     1861 LAYYTVRNFT LRNTKIKKGS QKGRPSGRVV TQYHYTQWPD MGVPEYSLPV LTFVRKAAYA
     1921 KRHAVGPVVV HCSAGVGRTG TYIVLDSMLQ QIQHEGTVNI FGFLKHIRSQ RNYLVQTEEQ
     1981 YVFIHDTLVE AILSKETEVL DSHIHAYVNA LLIPGPAGKT KLEKQFQLLS QSNIQQSDYS
     2041 AALKQCNREK NRTSSIIPVE RSRVGISSLS GEGTDYINAS YIMGYYQSNE FIITQHPLLH
     2101 TIKDFWRMIW DHNAQLVVMI PDGQNMAEDE FVYWPNKDEP INCESFKVTL MAEEHKCLSN
     2161 EEKLIIQDFI LEATQDDYVL EVRHFQCPKW PNPDSPISKT FELISVIKEE AANRDGPMIV
     2221 HDEHGGVTAG TFCALTTLMH QLEKENSVDV YQVAKMINLM RPGVFADIEQ YQFLYKVILS
     2281 LVSTRQEENP STSLDSNGAA LPDGNIAESL ESLV
//