LOCUS BC084566 1670 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens farnesyltransferase, CAAX box, alpha, mRNA (cDNA clone
MGC:99680 IMAGE:6423445), complete cds.
ACCESSION BC084566
VERSION BC084566.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1670)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1670)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-OCT-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: l Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 66882377.
FEATURES Location/Qualifiers
source 1..1670
/db_xref="H-InvDB:HIT000266075"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:99680 IMAGE:6423445"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1670
/gene="FNTA"
/gene_synonym="FPTA"
/gene_synonym="PGGT1A"
/db_xref="GeneID:2339"
/db_xref="HGNC:HGNC:3782"
/db_xref="MIM:134635"
CDS 9..1148
/gene="FNTA"
/gene_synonym="FPTA"
/gene_synonym="PGGT1A"
/codon_start=1
/product="farnesyltransferase, CAAX box, alpha"
/protein_id="AAH84566.1"
/db_xref="GeneID:2339"
/db_xref="HGNC:HGNC:3782"
/db_xref="MIM:134635"
/translation="MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAG
EAVASPMDDGFVSLDSPSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDY
FRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIE
EQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDN
ELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESA
WNYLKGILQDRGLSKYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDIL
NKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTENDSPTNVQQ"
BASE COUNT 521 a 339 c 389 g 421 t
ORIGIN
1 gaggcgagat ggcggccacc gagggggtcg gggaggctgc gcaagggggc gagcccgggc
61 agccggcgca acccccgccc cagccgcacc caccgccgcc ccagcagcag cacaaggaag
121 agatggcggc cgaggctggg gaagccgtgg cgtcccccat ggacgacggg tttgtgagcc
181 tggactcgcc ctcctatgtc ctgtacaggg acagagcaga atgggctgat atagatccgg
241 tgccgcagaa tgatggcccc aatcccgtgg tccagatcat ttatagtgac aaatttagag
301 atgtttatga ttacttccga gctgtcctgc agcgtgatga aagaagtgaa cgagctttta
361 agctaacccg ggatgctatt gagttaaatg cagccaatta tacagtgtgg catttccgga
421 gagttctttt gaagtcactt cagaaggatc tacatgagga aatgaactac atcactgcaa
481 taattgagga gcagcccaaa aactatcaag tttggcatca taggcgagta ttagtggaat
541 ggctaagaga tccatctcag gagcttgaat ttattgctga tattcttaat caggatgcaa
601 agaattatca tgcctggcag catcgacaat gggttattca ggaatttaaa ctttgggata
661 atgagctgca gtatgtggac caacttctga aagaggatgt gagaaataac tctgtctgga
721 accaaagata cttcgttatt tctaacacca ctggctacaa tgatcgtgct gtattggaga
781 gagaagtcca atacactctg gaaatgatta aactagtacc acataatgaa agtgcatgga
841 actatttgaa agggattttg caggatcgtg gtctttccaa atatcctaat ctgttaaatc
901 aattacttga tttacaacca agtcatagtt ccccctacct aattgccttt cttgtggata
961 tctatgaaga catgctagaa aatcagtgtg acaataagga agacattctt aataaagcat
1021 tagagttatg tgaaatccta gctaaagaaa aggacactat aagaaaggaa tattggagat
1081 acattggaag atcccttcaa agcaaacaca gcacagaaaa tgactcacca acaaatgtac
1141 agcaataaca ccatccagaa gaacttgatg gaatgctttt attttttatt aagggaccct
1201 gcaggagttt cacacgagag tggtccttcc ctttgcctgt ggtgtaaaag tgcatcacac
1261 aggtattgct ttttaacaag aactgatgct ccttgggtgc tgctgctact cagactagct
1321 ctaagtaatg tgattcttct aaagcaaagt cattggatgg gaggaggaag aaaaagtccc
1381 ataaaggaac ttttgtagtc ttatcaacat ataatctaat cccttagcat cagctcctcc
1441 ctcagtggta catgcgtcaa gatttgtagc agtaataact gcaggtcact tgtatgtaat
1501 ggatgtgagg tagccgaagt ttggttcagt aagcagggaa tacagtcgtt ccatcagagc
1561 tggtctgcac actcacatta tcttgctatc actgtaacca actaatgcca aaagaacggt
1621 tttgtaataa aattatagct gtatctaaaa acaaaaaaaa aaaaaaaaaa
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