LOCUS BC084556 2398 bp mRNA linear HUM 24-JAN-2005
DEFINITION Homo sapiens dedicator of cytokinesis 2, mRNA (cDNA clone
IMAGE:5933446), partial cds.
ACCESSION BC084556
VERSION BC084556.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2398)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2398)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (12-OCT-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Daniel McVicar, DBS/NCI
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: h Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..2398
/db_xref="H-InvDB:HIT000266065"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5933446"
/tissue_type="Blood, natural killer cell"
/clone_lib="NIH_MGC_106"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2398
/gene="DOCK2"
/gene_synonym="KIAA0209"
/db_xref="GeneID:1794"
/db_xref="MIM:603122"
CDS <1..1854
/gene="DOCK2"
/gene_synonym="KIAA0209"
/codon_start=1
/product="DOCK2 protein"
/protein_id="AAH84556.1"
/db_xref="GeneID:1794"
/db_xref="MIM:603122"
/translation="NNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQ
CASQVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDY
ELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERRED
FQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQII
NFYKSNYVQRFHYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQ
TTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYE
KAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEEC
FKNLKMKVEKEYGVREMPDFDDRRVGRPRSMLRSYRQMSIISLASMNSDCSTPSKPTS
ESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLK
RLSRKHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANT
SPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKSAEEGKQIPDSLSTDL"
BASE COUNT 665 a 619 c 596 g 518 t
ORIGIN
1 aacaacaggg aggagatgta cataaggtac ctgtacaaac tccgcgatct tcacctggac
61 tgtgacaatt acacagaggc tgcctacacg ctccttctcc acacctggct tctcaagtgg
121 tcggatgagc agtgtgcatc acaggtcatg cagacaggcc agcagcaccc ccagacacac
181 cggcagctga aggagacgct ctacgagacc atcataggct actttgacaa aggaaagatg
241 tgggaagagg ccataagtct gtgcaaggag ctggcggaac agtacgagat ggagatcttt
301 gactatgagc tgctcagcca gaacctgatc cagcaggcaa aattctatga aagcatcatg
361 aaaatcctca ggcccaaacc agactacttt gctgttggat actacggcca gggattcccc
421 tccttcctgc ggaacaaagt gttcatctac cgcgggaagg aatatgagcg aagagaagat
481 ttccagatgc agctgatgac ccagttcccc aatgcagaga agatgaacac cacctctgcc
541 ccgggagatg atgtgaagaa tgccccaggc cagtatatcc agtgcttcac tgtccagcct
601 gtcttggatg aacatcccag gttcaagaat aagccagtgc ctgaccagat tataaacttc
661 tacaaatcca actacgtgca aaggttccac tactcccggc ccgtgcgcag ggggaccgta
721 gacccagaga atgagtttgc ttccatgtgg attgagagaa cctccttcgt gactgcatac
781 aagctgccgg ggatcctgcg ctggtttgag gtggtgcaca tgtcgcagac cacaattagt
841 cctctggaga atgccataga aaccatgtcc acggccaatg agaagatcct gatgatgata
901 aaccagtacc agagtgatga gaccctcccc atcaacccac tctccatgct cctgaacggg
961 attgtggacc ctgctgtcat gggaggcttc gccaagtatg agaaggcctt cttcactgaa
1021 gagtatgtca gggaccaccc tgaggaccag gacaagctga cccacctcaa ggacctgatt
1081 gcatggcaga tccccttctt gggagctggg attaagatcc atgagaaaag ggtgtcagat
1141 aacttgcgac ccttccatga ccggatggag gaatgtttca agaacctgaa aatgaaggtg
1201 gagaaggagt acggtgtccg agagatgcct gactttgacg acaggagagt gggccgtccc
1261 aggtctatgc tgcgctcata cagacagatg tccatcatct ctctggcttc catgaattct
1321 gactgcagca cccccagcaa gcctacctca gagagctttg acctggaatt agcatcaccc
1381 aagacgccga gagtggagca ggaggaaccg atctccccgg ggagcaccct gcctgaggtc
1441 aagctgcgga ggtccaagaa gaggacaaag agaagcagcg tagtttttgc ggatgagaaa
1501 gcagctgcag agtcggacct gaagcggctt tccaggaagc atgagttcat gagtgacacc
1561 aacctctcgg agcatgcggc catccccctc aaggcgtctg tcctctctca aatgagcttt
1621 gccagccagt ccatgcctac catcccagcc ctggcgctct cagtggcagg catccctggg
1681 ttggatgagg ccaacacatc tccccgcctc agccagacct tcctccaact ctcagatggt
1741 gacaagaaga cactcacacg gaagaaggtc aatcagttct tcaagacaat gctggccagc
1801 aaatcggctg aagaaggcaa acagatccca gactcgctgt ccacggacct gtgagctgct
1861 gctgactagg gctgcatggg agagccaggg aggggagttt ctggaagagg aaagccatgc
1921 gtggaacatc gaagcctcag agagtgggag actgtcccca tcagttgtcc ttacttagag
1981 gagacagaga ggccaatcag gtcccagagc ttgagtgcta acaagcccag catcccctgg
2041 ggctgtgatc atggtggatg aggaagcctc aacgtagatt cctgaactca aggtaccagc
2101 aagaatgcct tctcccagtg tgctctcccc aacatcctag gcacagcttt cataacccag
2161 tttcttaggt gtaagaaact gtttttatct catttattaa gtctcagaac ttaacagaaa
2221 aggaagcctt ttaaatattc tttttaattt tattttagat taacagtttt gtactttaca
2281 tttttttata caaccaacca gtttcttttc tagccaatca tctctgaaga gttgctgttt
2341 cttactgaca ataaaaaatg ttctcttggt tcgaataaaa aaaaaaaaaa aaaaaaaa
//