LOCUS BC082986 3010 bp mRNA linear HUM 21-JUL-2008
DEFINITION Homo sapiens amyloid beta (A4) precursor protein-binding, family A,
member 2, mRNA (cDNA clone MGC:99508 IMAGE:6671740), complete cds.
ACCESSION BC082986
VERSION BC082986.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3010)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3010)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-SEP-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: p Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22035549.
FEATURES Location/Qualifiers
source 1..3010
/db_xref="H-InvDB:HIT000266023"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:99508 IMAGE:6671740"
/tissue_type="Ovary, teratocarcinoma"
/clone_lib="NIH_MGC_109"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3010
/gene="APBA2"
/gene_synonym="D15S1518E"
/gene_synonym="HsT16821"
/gene_synonym="LIN-10"
/gene_synonym="MGC:14091"
/db_xref="GeneID:321"
/db_xref="HGNC:HGNC:579"
/db_xref="MIM:602712"
CDS 187..2400
/gene="APBA2"
/gene_synonym="D15S1518E"
/gene_synonym="HsT16821"
/gene_synonym="LIN-10"
/gene_synonym="MGC:14091"
/codon_start=1
/product="APBA2 protein"
/protein_id="AAH82986.1"
/db_xref="GeneID:321"
/db_xref="HGNC:HGNC:579"
/db_xref="MIM:602712"
/translation="MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPE
GLELAALRPESPAPEEQECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIR
YCPEDDSYLEGMDCNGEEYLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDY
PDGQLPIPEDEPSVLEAHDQEEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGD
LEDQEEDIDQIVAEIKMSLSMTSITSASEASPEHGPEPGPEDSVEACPPIKASCSPSR
HEARPKSLNLLPEAKHPGDPQRGFKPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLN
GPVDNNNIPETKKVASFPSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNI
RMMQAQEAVSRVKNSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIAD
IGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAF
SVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEI
LGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQG
IIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGV
RVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI"
BASE COUNT 721 a 883 c 899 g 507 t
ORIGIN
1 gttgctgaat ctcctgtgga caaaccacca ataggccagg actgtcctgt ggacagacgg
61 ggtgagcctc ttcttgtgtc tggagattct gaaaagattt gatcaccagg agatttttcg
121 ggacattacc aaaccactca ttttagtggc tgcctccggg tgatgatggc tgtgtgaacg
181 actgccatgg cccaccggaa gcttgagagc gtggggagcg gcatgttgga ccatagggtg
241 agaccaggtc ctgtccctca cagccaggag cccgagagcg aggacatgga gctgcccttg
301 gagggctatg tgcccgaggg cctggagctg gctgccctgc ggccagagag ccccgcgcca
361 gaggaacagg agtgccacaa ccacagcccc gatggggact ccagctctga ctacgtgaac
421 aacacctctg aggaggagga ctatgacgag ggcctccctg aggaggagga gggcatcacc
481 tactacatcc gctactgccc tgaggacgac agctacctag agggcatgga ctgcaacggg
541 gaggagtacc tggcccacag tgcacaccct gtggacactg atgagtgcca ggaggcggtg
601 gaggagtgga cggactcggc gggcccgcac ccccacggcc acgaggctga aggcagccag
661 gactacccag acggccaact gcccattccg gaggatgagc cctccgtcct tgaggcccat
721 gaccaggaag aagatggtca ctactgtgcc agcaaagagg gctaccagga ctactacccc
781 gaggaggcca acgggaacac cggcgcctcc ccctaccgcc tgaggcgtgg ggatggggac
841 ctggaggacc aggaggagga cattgaccag atcgtggcag agatcaagat gagtctgagc
901 atgaccagca tcaccagcgc cagtgaggcc agccccgagc atgggcctga gccagggcct
961 gaggactctg tagaggcctg cccacccatc aaggccagct gcagccccag caggcacgag
1021 gcgaggccca agtcgctgaa cctccttccc gaggccaagc accccggaga cccccagaga
1081 ggcttcaagc ccaagaccag gaccccagaa gagaggccga agtggcccca cgagcaggtt
1141 tgcaatggtc tggagcagcc aaggaagcag cagcgctctg atctcaatgg acctgttgac
1201 aataacaaca ttccagagac aaagaaggtg gcatcatttc caagttttgt ggctgttcca
1261 gggccctgcg aaccagaaga cctcatcgac gggatcatct ttgctgccaa ttacctgggg
1321 tccacccagc tgctatcaga acggaaccct tccaaaaaca tcagaatgat gcaagcgcag
1381 gaggccgtca gccgggtcaa gaattctgag ggggatgccc agacgctgac ggaagtggac
1441 ctcttcattt ccacccagag gatcaaggtt ttaaatgcag acacgcagga aaccatgatg
1501 gaccacgcct tgcgtaccat ctcctacatc gccgacattg ggaacattgt agtgctgatg
1561 gccagacgcc gcatgccccg gtcagcctct caggactgca tcgagaccac gcccggggcc
1621 caggaaggca agaagcagta taagatgatc tgccatgtgt tcgagtcgga ggatgcccag
1681 ctcatcgccc agtctatcgg ccaggccttc agcgtggcct accaggagtt cctgcgagcc
1741 aatggcatca accccgaaga cttgagccag aaggaataca gcgacatcat caacacccag
1801 gagatgtaca acgacgacct catccacttc tcaaactcgg agaactgcaa ggagctgcag
1861 ctggagaagc acaagggcga gatcctgggc gtggtggtgg tggagtcggg ctggggctcc
1921 atcctgccca cggtgatcct ggccaacatg atgaatggtg gcccggctgc ccgctcgggg
1981 aagctgagca tcggggacca gatcatgtcc atcaatggca ccagcctggt ggggctgccc
2041 ctcgccacct gccaaggcat catcaagggc ctgaagaacc agacacaggt gaagctcaac
2101 attgtcagct gtcccccggt caccacggtc cttatcaagc ggccagacct caagtaccag
2161 ctgggcttca gcgtgcagaa tggaattatc tgcagcctca tgagaggggg cattgctgag
2221 cgagggggcg tccgtgtggg ccaccgcatc atcgagatca acgggcagag cgtggtggcc
2281 acagcccacg agaagatagt ccaagctctg tccaactcgg tcggagagat ccacatgaag
2341 accatgcccg ccgccatgtt caggctcctc acgggtcagg agaccccgct gtacatctag
2401 gccaccccag cctggccacg cagccaggac accgggcagg gccgcccggg cccagaggag
2461 ctgggagccg ggccgcagac ttgaccccga cgccacagcc cagccacgga cgctggctcc
2521 ccaaagggtg tgccctcacc acccacttga tttttttcat tttgccaaaa aggggtatgt
2581 ctttatcaaa ggagagtcac agaacaaatg tttgtttgta aagcgttcca agtattttgc
2641 cacgttctgg actgtcttct ccctgaacaa gccagggtgt gtctcggtag ctgtgcgtgg
2701 tgtggagtgt gtgtctttcc tccctgaagc tgtgcggagc gaactggcgc ctccgaggga
2761 cgcggctccc ggggcagggc agccgtcacc cctgcctccc gcccccttgg ctgggacgtc
2821 tggggtcctg tggggccccc acaatggtcc caaacagctg cctctgccac tgactgcagg
2881 gacacgggca gcctggctcc caggacacga cttgtaatga aagtttgggg acatgtgatt
2941 gattgattga ttgtaaataa aggatgatgg ccacaacaaa aaaaaaaaaa aaaaaaaaaa
3001 aaaaaaaaaa
//