LOCUS BC080647 2622 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens scavenger receptor class B, member 1, mRNA (cDNA clone
MGC:99530 IMAGE:6576008), complete cds.
ACCESSION BC080647
VERSION BC080647.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2622)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2622)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: n Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33620766.
FEATURES Location/Qualifiers
source 1..2622
/db_xref="H-InvDB:HIT000265909"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:99530 IMAGE:6576008"
/tissue_type="Prostate, carcinoma"
/clone_lib="NIH_MGC_40"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2622
/gene="SCARB1"
/gene_synonym="CLA-1"
/gene_synonym="CLA1"
/gene_synonym="SR-BI"
/gene_synonym="SRB1"
/db_xref="GeneID:949"
/db_xref="HGNC:HGNC:1664"
/db_xref="MIM:601040"
CDS 128..1657
/gene="SCARB1"
/gene_synonym="CLA-1"
/gene_synonym="CLA1"
/gene_synonym="SR-BI"
/gene_synonym="SRB1"
/codon_start=1
/product="scavenger receptor class B, member 1"
/protein_id="AAH80647.1"
/db_xref="GeneID:949"
/db_xref="HGNC:HGNC:1664"
/db_xref="MIM:601040"
/translation="MGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKNV
RIDPSSLSFNMWKEIPIPFYLSVYFFDVMNPSEILKGEKPQVRERGPYVYREFRHKSN
ITFNNNDTVSFLEYRTFQFQPSKSHGSESDYIVMPNILVLGAAVMMENKPMTLKLIMT
LAFTTLGERAFMNRTVGEIMWGYKDPLVNLINKYFPGMFPFKDKFGLFAELNNSDSGL
FTVFTGVQNISRIHLVDKWNGLSKVDFWHSDQCNMINGTSGQMWPPFMTPESSLEFYS
PEACRSMKLMYKESGVFEGIPTYRFVAPKTLFANGSIYPPNEGFCPCLESGIQNVSTC
RFSAPLFLSHPHFLNADPVLAEAVTGLHPNQEAHSLFLDIHPVTGIPMNCSVKLQLSL
YMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHTFYTQLVLMPKVMHYAQYVLLA
LGCVLLLVPVICQIRSQEKCYLFWSSSKKGSKDKEAIQAYSESLMTSAPKGSVLQEAK
L"
BASE COUNT 527 a 839 c 711 g 545 t
ORIGIN
1 cccggatcca ccgtgcctct gcggcctgcg tgcccggagt ccccgcctgt gtcgtctctg
61 tcgccgtccc cgtctcctgc caggcgcgga gccctgcgag ccgcgggtgg gccccaggcg
121 cgcagacatg ggctgctccg ccaaagcgcg ctgggctgcc ggggcgctgg gcgtcgcggg
181 gctactgtgc gctgtgctgg gcgctgtcat gatcgtgatg gtgccgtcgc tcatcaagca
241 gcaggtcctt aagaacgtgc gcatcgaccc cagtagcctg tccttcaaca tgtggaagga
301 gatccctatc cccttctatc tctccgtcta cttctttgac gtcatgaacc ccagcgagat
361 cctgaagggc gagaagccgc aggtgcggga gcgcgggccc tacgtgtaca gggagttcag
421 gcacaaaagc aacatcacct tcaacaacaa cgacaccgtg tccttcctcg agtaccgcac
481 cttccagttc cagccctcca agtcccacgg ctcggagagc gactacatcg tcatgcccaa
541 catcctggtc ttgggtgcgg cggtgatgat ggagaataag cccatgaccc tgaagctcat
601 catgaccttg gcattcacca ccctcggcga acgtgccttc atgaaccgca ctgtgggtga
661 gatcatgtgg ggctacaagg acccccttgt gaatctcatc aacaagtact ttccaggcat
721 gttccccttc aaggacaagt tcggattatt tgctgagctc aacaactccg actctgggct
781 cttcacggtg ttcacggggg tccagaacat cagcaggatc cacctcgtgg acaagtggaa
841 cgggctgagc aaggttgact tctggcattc cgatcagtgc aacatgatca atggaacttc
901 tgggcaaatg tggccgccct tcatgactcc tgagtcctcg ctggagttct acagcccgga
961 ggcctgccga tccatgaagc taatgtacaa ggagtcaggg gtgtttgaag gcatccccac
1021 ctatcgcttc gtggctccca aaaccctgtt tgccaacggg tccatctacc cacccaacga
1081 aggcttctgc ccgtgcctgg agtctggaat tcagaacgtc agcacctgca ggttcagtgc
1141 ccccttgttt ctctcccatc ctcacttcct caacgccgac ccggttctgg cagaagcggt
1201 gactggcctg caccctaacc aggaggcaca ctccttgttc ctggacatcc acccggtcac
1261 gggaatcccc atgaactgct ctgtgaaact gcagctgagc ctctacatga aatctgtcgc
1321 aggcattgga caaactggga agattgagcc tgtggtcctg ccgctgctct ggtttgcaga
1381 gagcggggcc atggaggggg agactcttca cacattctac actcagctgg tgttgatgcc
1441 caaggtgatg cactatgccc agtacgtcct cctggcgctg ggctgcgtcc tgctgctggt
1501 ccctgtcatc tgccaaatcc ggagccaaga gaaatgctat ttattttgga gtagtagtaa
1561 aaagggctca aaggataagg aggccattca ggcctattct gaatccctga tgacatcagc
1621 tcccaagggc tctgtgctgc aggaagcaaa actgtagggt cctgaggaca ccgtgagcca
1681 gccaggcctg gccgctgggc ctgaccggcc ccccagcccc tacaccccgc ttctcccgga
1741 ctctcccagc ggacagcccc ccagccccac agcctgagcc tcccagctgc catgtgcctg
1801 ttgcacacct gcacacacgc cctggcacac atacacacat gcgtgcaggc ttgtgcagac
1861 actcagggat ggagctgctg ctgaagggac ttgtagggag aggctcgtca acaagcactg
1921 ttctggaacc ttctctccac gtggcccaca ggcctgacca caggggctgt gggtcctgcg
1981 tccccttcct cgggtgagcc tggcctgtcc cgttcagccg ttgggcccag gcttcctccc
2041 ctccaaggtg aaacactgca gtcccggtgt ggtggctccc catgcaggac gggccaggct
2101 gggagtgccg ccttcctgtg ccaaattcag tggggactca gtgcccaggc cctggccacg
2161 agctttggcc ttggtctacc tgccaggcca ggcaaagcgc ctttacacag gcctcggaaa
2221 acaatggagt gagcacaaga tgccctgtgc agctgcccga gggtctccgc ccaccccggc
2281 cggactttga tccccccgaa gtcttcacag gcactgcatc gggttgtctg gcgccctttt
2341 cctccagcct aaactgacat catcctatgg actgagccgg ccactctctg gccgaagtgg
2401 ccgcaggctg tgcccccgag ctgcccccac cccctcacag ggtccctcag attataggtg
2461 cccaggctga ggtgaagagg cctgggggcc ctgccttccg ggcgctcctg gaccctgggg
2521 caaacctgtg acccttttct actggaatag aaatgagttt tatcatcttt gaaaaataat
2581 tcactcttga agtaataaac gtttaaaaaa aaaaaaaaaa aa
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