LOCUS BC080551 2354 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens hypoxia inducible factor 3, alpha subunit, mRNA (cDNA
clone MGC:99497 IMAGE:6250259), complete cds.
ACCESSION BC080551
VERSION BC080551.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2354)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2354)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: i Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23065537.
FEATURES Location/Qualifiers
source 1..2354
/db_xref="H-InvDB:HIT000265820"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:99497 IMAGE:6250259"
/tissue_type="Pancreas, ductal carcinoma"
/clone_lib="NIH_MGC_110"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2354
/gene="HIF3A"
/gene_synonym="HIF-3A"
/gene_synonym="HIF-3A4"
/gene_synonym="IPAS"
/gene_synonym="MOP7"
/gene_synonym="PASD7"
/db_xref="GeneID:64344"
/db_xref="HGNC:HGNC:15825"
/db_xref="MIM:609976"
CDS 3..2012
/gene="HIF3A"
/gene_synonym="HIF-3A"
/gene_synonym="HIF-3A4"
/gene_synonym="IPAS"
/gene_synonym="MOP7"
/gene_synonym="PASD7"
/codon_start=1
/product="hypoxia inducible factor 3, alpha subunit"
/protein_id="AAH80551.1"
/db_xref="GeneID:64344"
/db_xref="HGNC:HGNC:15825"
/db_xref="MIM:609976"
/translation="MALGLQRARSTTELRKEKSRDAARSRRSQETEVLYQLAHTLPFA
RGVSAHLDKASIMRLTISYLRMHRLCAAGEWNQVGAGGEPLDACYLKALEGFVMVLTA
EGDMAYLSENVSKHLGLSQLELIGHSIFDFIHPCDQEELQDALTPQQTLSRRKVEAPT
ERCFSLRMKSTLTSRGRTLNLKAATWKVLNCSGHMRAYKPPAQTSPAGSPDSEPPLQC
LVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDDRIAEVAGYSPDDLIGCSAYE
YIHALDSDAVSKSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSESI
VCVHFLISRVEETGVVLSLEQTEQHSRRPIQRGAPSQKDTPNPGDSLDTPGPRILAFL
HPPSLSEAALAADPRRFCSPDLRRLLGPILDGASVAATPSTPLATRHPQSPLSADLPD
ELPVGTENVHRLFTSGKDTEAVETDLDIAQDADALDLEMLAPYISMDDDFQLNASEQL
PRAYHRPLGAVPRPRARSFHGLSPPALEPSLLPRWGSDPRLSCSSPSRGDPSASSPMA
GARKRTLAQSSEDEDEGVELLGVRPPKRSPSPEHENFLLFPLSLSFLLTGGPAPGSLQ
DPSTPLLNLNEPLGLGPSLLSPYSDEDTTQPGGPFQPRAGSAQAD"
BASE COUNT 483 a 819 c 646 g 406 t
ORIGIN
1 ccatggcgct ggggctgcag cgcgcaaggt cgaccacgga gctgcgcaag gaaaagtccc
61 gggatgcggc ccgcagccgg cgcagccagg agaccgaggt gctgtaccag ctggctcaca
121 cgctgccctt cgcccgcggc gtcagcgccc acctggacaa ggcctctatc atgcgcctca
181 ccatcagcta cctgcgcatg caccgcctct gcgccgcagg ggagtggaac caggtgggag
241 cagggggaga accactggat gcctgctacc tgaaggccct ggagggcttc gtcatggtgc
301 tcaccgccga gggagacatg gcttacctgt cggagaatgt cagcaaacac ctgggcctca
361 gtcagctgga gctcattgga cacagcatct ttgatttcat ccacccctgt gaccaagagg
421 agcttcagga cgccctgacc ccccagcaga ccctgtccag gaggaaggtg gaggccccca
481 cggagcggtg cttctccttg cgcatgaaga gtacactcac cagccgcggg cgcaccctca
541 acctcaaggc ggccacctgg aaggtgctga actgctctgg acatatgagg gcctacaagc
601 cacctgcgca gacttctcca gctgggagcc ctgactcaga gcccccgctg cagtgcctgg
661 tgctcatctg cgaagccatc ccccacccag gcagcctgga gcccccactg ggccgagggg
721 ccttcctcag ccgccacagc ctggacatga agttcaccta ctgtgacgac aggattgcag
781 aagtggctgg ctatagtccc gatgacctga tcggctgttc cgcctacgag tacatccacg
841 cgctggactc cgacgcggtc agcaagagca tccacacctt gctgagcaag ggccaggcag
901 taacagggca gtatcgcttc ctggcccgga gtggtggcta cctgtggacc cagacccagg
961 ccacagtggt gtcaggggga cggggccccc agtcggagag tatcgtctgt gtccattttt
1021 taatcagccg ggtggaagag accggagtgg tgctgtccct ggagcaaacg gagcaacatt
1081 ctcgcagacc cattcagcgg ggcgccccct ctcagaagga cacccctaac cctggggaca
1141 gccttgacac ccctggcccc cggatccttg ccttcctgca cccgccttcc ctgagcgagg
1201 ctgccctggc cgctgacccc cgccgtttct gcagccctga cctccgtcgc ctcctgggac
1261 ccatcctgga tggggcttca gtagcagcca ctcccagcac cccgctggcc acacggcacc
1321 cccaaagtcc tctttcggct gatctcccag atgaactacc tgtgggcacc gagaatgtgc
1381 acagactctt cacctccggg aaagacactg aggcagtgga gacagattta gatatagctc
1441 aggatgctga tgctctggat ttggagatgc tggcccccta catctccatg gatgatgact
1501 tccagctcaa cgccagcgag cagctaccca gggcctacca cagacctctg ggggctgtcc
1561 cccggccccg tgctcggagc ttccatggcc tgtcacctcc agcccttgag ccctccctgc
1621 taccccgctg ggggagtgac ccccggctga gctgctccag cccttccaga ggggacccct
1681 cagcatcctc tcccatggct ggggctcgga agaggaccct ggcccagagc tcagaggacg
1741 aggacgaggg agtggagctg ctgggagtga gacctcccaa aaggtccccc agcccagaac
1801 acgaaaactt tctgctcttt cctctcagcc tgagtttcct tctgacagga ggaccagccc
1861 cagggagcct gcaggacccc agcaccccac tcctgaacct gaatgagccc ctgggcctgg
1921 gcccctcact gctctctccg tactcagacg aggacactac ccagcccggg ggccccttcc
1981 agccaagggc aggctcagcc caggctgact gagccggctc ctctccccat ctgccttctc
2041 ctcccccaga aaggacctca accacactcc acgccggcag ccaacgcaca ggatgggggc
2101 gccaggagag gggcccctct ctcctctatg taccccctgc ccacctcggg cctacctcag
2161 ccctcacccc tctgcctgct cccaatctgg gggctctctg gggtggtctc agctcagtga
2221 cctctgggag gtggtccctg gccccctcct ccttctctca ggatttctct tggggttctc
2281 aatacttggt tacctcatta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2341 aaaaaaaaaa aaaa
//