LOCUS BC080541 2308 bp mRNA linear HUM 24-NOV-2004
DEFINITION Homo sapiens receptor tyrosine kinase-like orphan receptor 1, mRNA
(cDNA clone IMAGE:5477978), complete cds.
ACCESSION BC080541
VERSION BC080541.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2308)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2308)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: g Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4826867
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..2308
/db_xref="H-InvDB:HIT000265810"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5477978"
/tissue_type="Brain, astrocytoma, grade IV"
/clone_lib="NIH_MGC_98"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..2308
/gene="ROR1"
/gene_synonym="dJ537F10.1"
/gene_synonym="NTRKR1"
/db_xref="GeneID:4919"
/db_xref="MIM:602336"
CDS 400..1581
/gene="ROR1"
/gene_synonym="dJ537F10.1"
/gene_synonym="NTRKR1"
/codon_start=1
/product="ROR1 protein"
/protein_id="AAH80541.1"
/db_xref="GeneID:4919"
/db_xref="MIM:602336"
/translation="MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTS
SWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEP
RRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGY
SDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDK
CSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMILMR
LKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQC
QPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACG
K"
BASE COUNT 608 a 614 c 593 g 493 t
ORIGIN
1 gttgagcgag agagggagcg tggagagctg gagcagccgc caccgccgcc gccgagggag
61 ccccgggacg gcagcccctg ggcgcagggt gcgctgttct cggagtccga cccagggcga
121 ctcacgccca ctggtgcgac ccggacagcc tgggactgac ccgccggccc aggcgaggct
181 gcagccagag ggctgggaag ggatcgcgct cgcggcatcc agaggcggcc aggcggaggc
241 gagggagcag gttagaggga caaagagctt tgcagacgtc cccggcgtcc tgcgagcgcc
301 agcggccggg acgaggcggc cgggagcccg ggaagagccc gtggatgttc tgcgcgcggc
361 ctgggagccg ccgccgccgc cgcctcagcg agaggaggaa tgcaccggcc gcgccgccgc
421 gggacgcgcc cgccgctcct ggcgctgctg gccgcgctgc tgctggccgc acgcggggct
481 gctgcccaag aaacagagct gtcagtcagt gctgaattag tgcctacctc atcatggaac
541 atctcaagtg aactcaacaa agattcttac ctgacccttg atgaaccaat gaataacatc
601 accacgtctc tgggccagac agcagaactg cactgcaaag tctctgggaa tccacctccc
661 accatccgct ggttcaaaaa tgatgctcct gtggtccagg agccccggag gctctccttt
721 cggtccacca tctatggctc tcggctgcgg attagaaacc tcgacaccac agacacaggc
781 tacttccagt gcgtggcaac aaacggcaag gaggtggttt cttccactgg agtcttgttt
841 gtcaagtttg gcccccctcc cactgcaagt ccaggatact cagatgagta tgaagaagat
901 ggattctgtc agccatacag agggattgca tgtgcaagat ttattggcaa ccgcaccgtc
961 tatatggagt ctttgcacat gcaaggggaa atagaaaatc agatcacagc tgccttcact
1021 atgattggca cttccagtca cttatctgat aagtgttctc agttcgccat tccttccctg
1081 tgccactatg ccttcccgta ctgcgatgaa acttcatccg tcccaaagcc ccgtgacttg
1141 tgtcgcgatg aatgtgaaat cctggagaat gtcctgtgtc aaacagagta catttttgca
1201 agatcaaatc ccatgattct gatgaggctg aaactgccaa actgtgaaga tctcccccag
1261 ccagagagcc cagaagctgc gaactgtatc cggattggaa ttcccatggc agatcctata
1321 aataaaaatc acaagtgtta taacagcaca ggtgtggact accgggggac cgtcagtgtg
1381 accaaatcag ggcgccagtg ccagccatgg aattcccagt atcctcacac acacactttc
1441 accgcccttc gtttcccaga gctgaatgga ggccattcct actgccgcaa cccagggaat
1501 caaaaggaag ctccctggtg cttcaccttg gatgaaaact ttaagtctga tctgtgtgac
1561 atcccagctt gcggtaaata gaagtcattg cccctaatgt attcaatcat ctttaaagat
1621 ccctatccta cccctcttat ttaggagaat cctataaggg gggcaaagaa aatggacagt
1681 atttgcttga tctcaatctg gttttagggt aaaccttgcc gtttctacat aaaacacctc
1741 gtaaggtacc aaaacacgtt ctcaagaagt caactgcctt tatacctgca gccattgcac
1801 tcatggatgt aacagggacc cagcccttca gaggcacagt tgagacagtt tatcacattg
1861 atttttatag aaaaagatgt tacccagaat ggtctgcgtc caagtggacc ttttcagcaa
1921 aaaaaggaat attggaagca ggaagaaatt gttttctgta tgccttaaga acaccacaag
1981 gcaggatgaa tctacaacca ttactcggtc atccaggaca atctgtgggt aaactgtgtc
2041 cttcgttatg tctgttaata ctgcagaaga agcatatagg tatctagtaa gaaaatggaa
2101 ttcctgagtc agttaactgt tcctttttct agaaaatgtt tggagaaaat aatgaaaatg
2161 ggccaagcat ggtggcttat acctgtaatc ccaacactct aggaaggccg aggcaggagg
2221 atcatttgag cccaggggtt caagaccagc ccaggcaaca tagtgagact ccatctctac
2281 caaaaaaaag aaaaaaaaaa aaaaaaaa
//