LOCUS BC078659 6901 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens latent transforming growth factor beta binding protein
2, mRNA (cDNA clone MGC:87426 IMAGE:30343778), complete cds.
ACCESSION BC078659
VERSION BC078659.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6901)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6901)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-AUG-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 168 Row: m Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46389563.
FEATURES Location/Qualifiers
source 1..6901
/db_xref="H-InvDB:HIT000265746"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87426 IMAGE:30343778"
/tissue_type="Placenta, normal"
/clone_lib="NIH_MGC_147"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..6901
/gene="LTBP2"
/gene_synonym="C14orf141"
/gene_synonym="MSTP031"
/db_xref="GeneID:4053"
/db_xref="HGNC:HGNC:6715"
/db_xref="MIM:602091"
CDS 294..5759
/gene="LTBP2"
/gene_synonym="C14orf141"
/gene_synonym="MSTP031"
/codon_start=1
/product="latent transforming growth factor beta binding
protein 2"
/protein_id="AAH78659.1"
/db_xref="GeneID:4053"
/db_xref="HGNC:HGNC:6715"
/db_xref="MIM:602091"
/translation="MRPRTKARSPGRALRNPWRGFLPLTLALFVGAGHAQRDPVGRYE
PAGGDANRLRRPGGSYPAAAAAKVYSLFREQDAPVAGLQPVERAQPGWGSPRRPTEAE
ARRPSRAQQSRRVQPPAQTRRSTPLGQQQPAPRTRAAPALPRLGTPQRSGAAPPTPPR
GRLTGRNVCGGQCCPGWTTANSTNHCIKPVCEPPCQNRGSCSRPQLCVCRSGFRGARC
EEVIPDEEFDPQNSRLAPRRWAERSPNLRRSSAAGEGTLARAQPPAPQSPPAPQSPPA
GTLSGLSQTHPSQQHVGLSRTVRLHPTATASSQLSSNALPPGPGLEQRDGTQQAVPLE
HPSSPWGLNLTEKIKKIKIVFTPTICKQTCARGHCANSCERGDTTTLYSQGGHGHDPK
SGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPIPQPDREPPGRGSRPRALLE
APLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQIHQVAQVRGGVEEALVENSVE
TRPPPWLPASPGHSLWDSNNIPARSGEPPRPLPPAAPRPRGLLGRCYLNTVNGQCANP
LLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDIN
ECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGT
CTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGYTYASSDIRLS
MRKAEEEELARPPREQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVT
TSVTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVC
GPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCY
PGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDIN
ECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEG
SFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDG
TACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC
LGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCA
PGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDE
CEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCD
NTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEE
YDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAEC
CCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGP
GLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLACENGECVNTEGSFHCF
CSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECC
CQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSI
YGPDGAPFYNYLGPEDTVPDPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPEPP
AGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP
AVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCTAKE"
BASE COUNT 1428 a 2194 c 2069 g 1210 t
ORIGIN
1 ccaaaaataa aaccgtccgg gtccccttca gacggctgca ggcacaggga ggaggcgcga
61 aggtgcagca gccgtgcgag cccagctgga gtaggagcgc ggactcgagg ctcggggcgc
121 gcagccctcg ttccgccgag agccgggccc ccagtcggcc gcttcagggc cccctagact
181 cagagaagct ggccgccggg cggggccggg agaacagccc gcgggcgtcc agcgtgccga
241 ccacaaagct cttcgcggtg cccgcgcgca ccactctcca gccgccccgc gccatgaggc
301 cgcggaccaa agcccgcagc ccggggcgcg ccctgcggaa cccctggaga ggcttcctgc
361 cgctcaccct ggctctcttc gtgggcgcgg gtcatgccca aagggacccc gtagggagat
421 acgagccggc tggtggagac gcgaatcgac tgcggcgccc tgggggcagc tacccggcag
481 cggctgcagc caaggtgtac agtctgttcc gggagcagga cgcgcctgtc gcgggcttgc
541 agcccgtgga gcgggcccag ccgggctggg ggagccccag gaggcccacc gaggcggagg
601 ccaggaggcc gtcccgcgcg cagcagtcgc ggcgtgtcca gccacctgcg cagacccgga
661 gaagcactcc cctgggccag cagcaaccag caccccggac ccgggccgcg ccggctctcc
721 cacgcctggg gaccccacag cggtctgggg ctgcgccccc aaccccgccg cgagggcgac
781 tcacggggag gaacgtctgc gggggacagt gctgcccagg atggacaaca gcaaacagca
841 ccaaccactg tatcaaaccc gtttgcgagc cgccgtgcca gaaccggggc tcctgcagcc
901 gcccgcagct ctgtgtctgc cgctctggtt tccgtggagc ccgctgcgag gaggtcattc
961 ccgatgagga atttgacccc cagaactcca ggctggcacc tcgacgctgg gccgagcgtt
1021 cacccaacct gcgcaggagc agtgcggctg gagagggcac cttggccaga gcacagccgc
1081 cagcaccaca gtcgccgccc gcaccacagt cgccaccagc tgggaccctg agtggcctca
1141 gccagaccca cccttcccag cagcacgtgg ggttgtcccg cactgtccga cttcacccga
1201 ctgccacggc cagtagccag ctctcttcca acgccctgcc cccgggacca ggccttgagc
1261 agagagatgg cacccaacag gcggtacctc tggagcaccc ctcatccccc tgggggctga
1321 acctcacgga gaaaatcaag aagatcaaga tcgtcttcac tcccaccatc tgcaagcaga
1381 cctgtgcccg tggacactgt gccaacagct gtgagagggg cgacaccacc accctgtaca
1441 gccagggcgg ccatgggcac gatcccaagt ctggcttccg catctatttc tgccagatcc
1501 cctgcctgaa cggaggccgc tgcatcggca gggacgaatg ctggtgcccc gccaactcca
1561 ccgggaagtt ctgccacctg cctatcccgc agccggacag ggagcctcca gggagggggt
1621 cccgccccag ggccttgctg gaagccccac tgaagcagtc cactttcaca ctgccgctct
1681 ccaaccagct ggcctccgtg aacccctccc tggtgaaggt gcacattcac cacccacccg
1741 aggcctcagt gcagatccac caggtggccc aggtgcgggg cggggtggag gaggccctag
1801 tggagaacag cgtggagacc agacccccgc cctggctgcc tgccagccct ggccacagcc
1861 tctgggacag caacaacatc cctgctcggt ctggagagcc ccctcggcca ctgcccccag
1921 cagcacccag gcctcgagga ctgctgggcc ggtgttacct gaacactgtg aacggacagt
1981 gtgccaaccc tctgctggag ctgactaccc aggaggactg ctgtggcagt gtgggagcct
2041 tctggggggt gactttgtgt gccccatgcc cacccagacc agcctccccg gtgattgaga
2101 atggccagct ggagtgtcct caggggtaca agagactgaa cctcactcac tgccaagata
2161 tcaacgagtg cttgaccctg ggcctgtgca aggacgcgga gtgtgtgaat accaggggca
2221 gctacctgtg cacatgcaga cctggcctca tgctggatcc atcgcggagc cgctgtgtgt
2281 cggacaaggc aatctccatg ctgcagggac tgtgctaccg gtcgctgggg cccggcacct
2341 gcaccctgcc tttggcccag cggatcacca agcagatatg ctgctgcagc cgcgtgggca
2401 aagcatgggg cagcgagtgt gagaaatgcc ctctgcctgg cacagaggcc ttcagagaga
2461 tctgccctgc cggccacggc tacacctacg cgagctccga catccgcctg tccatgagga
2521 aagccgagga ggaggaactg gcaaggcccc caagggagca agggcagagg agcagcgggg
2581 cactgcccgg gccagcagag aggcagcccc tccgggtcgt cacggacacc tggcttgagg
2641 ccgggaccat ccctgacaag ggtgactctc aggctggcca ggtcacgacc agtgtcactc
2701 atgcacctgc ctgggtcaca gggaatgcca caaccccacc aatgcctgaa caggggattg
2761 cagagataca ggaagaacaa gtgaccccct ccaccgatgt gctggtgacc ctgagcaccc
2821 caggcattga cagatgcgct gctggagcca ccaacgtctg tggccctgga acctgcgtga
2881 acctccccga tggatacaga tgtgtctgca gccctggcta ccagctgcac cccagccagg
2941 cctactgcac agatgacaac gagtgtctga gggacccctg caagggaaaa gggcgctgca
3001 tcaaccgcgt ggggtcctac tcctgcttct gctaccctgg ctacactctg gccacctcag
3061 gggcgacaca ggagtgtcaa gatatcaatg agtgtgagca gccaggggtg tgcagcgggg
3121 ggcagtgcac caacaccgag ggctcgtacc actgcgagtg tgatcagggc tacatcatgg
3181 tcaggaaagg acactgccaa gatatcaacg aatgccgtca ccccggtacc tgccctgatg
3241 ggagatgcgt caattcccct ggctcctaca cttgtctggc ctgtgaggag ggctaccggg
3301 gccagagtgg gagctgtgta gatgtgaatg agtgtctgac tcccggggtc tgtgcccatg
3361 gaaagtgcac caacctagaa ggctccttca gatgctcttg tgagcagggc tatgaggtca
3421 cctcagatga gaagggctgc caagatgtgg atgagtgtgc cagccgggcc tcatgcccca
3481 caggcctctg cctcaacacg gagggctcct tcgcctgctc tgcctgtgag aacgggtact
3541 gggtgaatga agacggcact gcctgtgaag acctagatga gtgtgccttc ccgggagtct
3601 gcccctccgg agtctgcacc aacacggctg gctccttctc ctgcaaggac tgcgatgggg
3661 gctaccggcc cagccccctg ggtgactcct gtgaagatgt ggatgaatgt gaagaccccc
3721 agagcagctg cctgggaggc gagtgcaaga acactgtggg ctcctaccag tgcctctgtc
3781 cccagggctt ccagctggcc aatggcaccg tgtgtgagga tgtgaatgag tgcatggggg
3841 aggagcactg cgcaccacac ggcgagtgcc tcaacagcca cgggtctttc ttctgtctgt
3901 gcgcgcctgg cttcgtcagc gcagaggggg gcaccagctg ccaggatgtg gacgagtgtg
3961 ccaccacaga cccgtgtgtg ggagggcact gtgtcaacac cgagggctcc ttcaactgtc
4021 tatgtgagac tggcttccag ccctccccag agagtggaga gtgtgtggat attgacgagt
4081 gtgaggacta tggagacccg gtgtgtggca cctggaagtg tgaaaacagc cctggctcct
4141 accgctgtgt tctgggctgc cagcctggct tccacatggc cccgaacgga gactgcattg
4201 acatagacga gtgcgccaac gacaccatgt gtggcagcca cggcttctgt gacaacactg
4261 atggctcctt ccgctgcctc tgtgaccagg gcttcgagat ctctccctca ggctgggact
4321 gtgtggatgt gaacgagtgt gagcttatgc tggcggtatg tggggccgcg ctctgtgaga
4381 acgtggaggg ctccttcctg tgcctctgtg ccagtgacct ggaggagtac gatgcccagg
4441 aggggcactg ccgcccacgg ggggctggag gtcagagtat gtctgaggcc ccaacggggg
4501 accatgcccc ggcccccacc cgcatggact gctactccgg gcagaagggc catgcgccct
4561 gctccagtgt cctgggccgg aacaccacac aggctgaatg ctgctgcacc cagggcgcta
4621 gctggggaga tgcctgtgac ctctgcccgt ctgaggactc agctgaattc agcgagatct
4681 gccctagtgg aaaaggctac attcctgtgg aaggagcctg gacgtttgga cagaccatgt
4741 acacagatgc ggatgagtgt gtgatattcg ggcctggtct ctgcccgaac ggccggtgcc
4801 tcaacaccgt gcctggttat gtctgcctgt gcaatcccgg cttccactac gatgcttccc
4861 acaagaagtg tgaggatcac gatgagtgcc aggacctggc ctgtgagaat ggcgagtgcg
4921 tcaacacgga gggctccttc cactgcttct gcagcccccc gctcaccctg gacctcagcc
4981 agcagcgctg catgaacagc accagcagca cggaggacct ccctgaccac gacatccaca
5041 tggacatctg ctggaaaaaa gtcaccaatg atgtgtgcag cgaacccctg cgtgggcacc
5101 gcaccaccta cacggaatgc tgctgccagg acggcgaggc ctggagccag cagtgtgctc
5161 tgtgtccccc gaggagctct gaggtctatg ctcagctgtg caacgtggct cgcattgagg
5221 cagagcggga ggccggggtc cacttccggc caggctatga gtatggcccc gggcccgatg
5281 acctgcacta cagcatctat ggcccagatg gggccccctt ctacaactac ctgggccccg
5341 aggacaccgt ccctgatcct gccttcccca acacagccgg tcactcagcg gaccgcacac
5401 ccatccttga gtctcctttg cagccctcag aactccagcc ccactacgtg gccagccatc
5461 cagagccccc agccggcttc gaagggcttc aggcggagga gtgcggcatc ctgaacggct
5521 gtgagaatgg ccgctgtgtg cgcgtgcggg agggctacac ctgtgactgt tttgagggct
5581 tccagctgga tgcggcccac atggcctgcg tagatgtgaa tgagtgtgat gacttgaacg
5641 ggcctgctgt gctctgtgtc catggttact gcgagaacac agagggctcc taccgctgcc
5701 actgctcccc gggatatgtg gctgaggcag ggccccccca ctgcactgcc aaggagtagc
5761 agtcaggggt cagtgtggca actacctgga aatggcctcc agtcacaggc aggggccttg
5821 aggatgattt cctagctggg aagacaccgt gacatcaggc cagaggtttc caatcagcct
5881 tgcctgcttt catctctccc agcttagcct ctggctgtaa gcttcggtca ttgcctccat
5941 gcccttgctt ggctcaagca ccaccaatcg ctttaatgct tcagccaccg catgaggccc
6001 tgtccaccac ctttcctggc cttgctatgg gatgcttacc aaaggatggc cctcatccac
6061 cctcccaagc tgtgcgagca tgcaaggccc catggcctca cactgcagac acccctttcc
6121 agccacaatc caccatcatc ctgacgatcc cacaactggg acagaggcta catctgccct
6181 agggaggtcc ttcagaatct gtggagcaag aaaggatttg gggaagcttg gggactgact
6241 ccagagcccc ctcctaagaa ccatcaccac cactcagcca atctgttctg ggccctgatt
6301 ttgccacacc tccatcctgt agcccattct ctgaccccaa ggagtggcag aagatccctt
6361 cactcagaga agcaaggctg atattagctt gttgaatgta agagacacaa atgaagaaga
6421 acaaagagcc tgagaaagca gcaagaggac atgatgaaaa atacgtggag ttgatgagaa
6481 aggggagcca aggctttata cgtctaaaga aaatattcag tagctgaatc cgcccagtga
6541 tagcctgtgg gcaccagcag caagggctgc catgggatac agcacccatc tacaaagacc
6601 tctattacat aaacactgct tcttacagga aacaaacctc ttctgggatc tccttttgtg
6661 aaaaccagtt tgatgtgcta aaagtaaaag tctattttcc agtgtggtct tgttcagaag
6721 cagccagatt tccaatgttg tttttcccct ccactcagaa acccctgccc tttcccttca
6781 gaaaacgatg gcaggcattc ctctgagttt acaagcagag actcactcca acccaaacta
6841 gctgggagtt cagaaccatg gtggaataaa gaaatgtgca tctagaaaaa aaaaaaaaaa
6901 a
//