LOCUS BC077726 4494 bp mRNA linear HUM 19-JUN-2006
DEFINITION Homo sapiens sema domain, seven thrombospondin repeats (type 1 and
type 1-like), transmembrane domain (TM) and short cytoplasmic
domain, (semaphorin) 5B, mRNA (cDNA clone MGC:78583 IMAGE:6597493),
complete cds.
ACCESSION BC077726
VERSION BC077726.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4494)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4494)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-JUL-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 54 Row: p Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 39930366.
FEATURES Location/Qualifiers
source 1..4494
/db_xref="H-InvDB:HIT000265690"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:78583 IMAGE:6597493"
/tissue_type="Ovary, teratocarcinoma"
/clone_lib="NIH_MGC_109"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..4494
/gene="SEMA5B"
/gene_synonym="FLJ10372"
/gene_synonym="KIAA1445"
/gene_synonym="SemG"
/db_xref="GeneID:54437"
/db_xref="HGNC:HGNC:10737"
/db_xref="MIM:609298"
CDS 71..3526
/gene="SEMA5B"
/gene_synonym="FLJ10372"
/gene_synonym="KIAA1445"
/gene_synonym="SemG"
/codon_start=1
/product="sema domain, seven thrombospondin repeats (type
1 and type 1-like), transmembrane domain (TM) and short
cytoplasmic domain, (semaphorin) 5B"
/protein_id="AAH77726.1"
/db_xref="GeneID:54437"
/db_xref="HGNC:HGNC:10737"
/db_xref="MIM:609298"
/translation="MPCGFSPSPVAHHLVPGPPDTPAQQLRCGWTVGGWLLSLVRGLL
PCLPPGARTAEGPIMVLAGPLAVSLLLPSLTLLVSHLSSSQDVSSEPSSEQQLCALSK
HPTVAFEDLQPWVSNFTYPGARDFSQLALDPSGNQLIVGARNYLFRLSLANVSLLQAT
EWASSEDTRRSCQSKGKTEEECQNYVRVLIVAGRKVFMCGTNAFSPMCTSRQVGNLSR
TIEKINGVARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQ
YNSKWLNEPNFVAAYDIGLFAYFFLRENAVEHDCGRTVYSRVARVCKNDVGGRFLLED
TWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNL
SAISQAFNGPFRYQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSLQDAQRLFL
MSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRS
LHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQGACL
GARDPYCGWDGKQQRCSTLEDSSNMSLWTQNITACPVRNVTRDGGFGPWSPWQPCEHL
DGDNSGSCLCRARSCDSPRPRCGGLDCLGPAIHIANCSRNGAWTPWSSWALCSTSCGI
GFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVPIFWASWGSWSKCSSNCGG
GMQSRRRACENGNSCLGCGVEFKTCNPEGCPEVRRNTPWTPWLPVNVTQGGARQEQRF
RFTCRAPLADPHGLQFGRRRTETRTCPADGSGSCDTDALVEDLLRSGSTSPHTVSGGW
AAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWS
CWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACPEGWSPWS
EWSKCTDDGAQSRSRHCEELLPGSSACAGNSSQSRPCPYSEIPVILPASSMEEATGCA
GFNLIHLVATGISCFLGSGLLTLAVYLSCQHCQRQSQESTLVHPATPNHLHYKGGGTP
KNEKYTPMEFKTLNKNNLIPDDRANFYPLQQTNVYTTTYYPSPLNKHSFRPEASPGQR
CFPNS"
BASE COUNT 868 a 1448 c 1304 g 874 t
ORIGIN
1 gggaaccggg cacctgcacc cgcctctggg agtgagtggc tccagctggt gcctggcctg
61 tgtctcttgg atgccctgtg gcttcagtcc gtctcctgtt gcccaccacc tcgtccctgg
121 gccgcctgat accccagccc aacagctaag gtgtggatgg acagtagggg gctggcttct
181 ctcactggtc aggggtcttc tcccctgtct gcctcccgga gctaggactg cagaggggcc
241 tatcatggtg cttgcaggcc ccctggctgt ctcgctgttg ctgcccagcc tcacactgct
301 ggtgtcccac ctctccagct cccaggatgt ctccagtgag cccagcagtg agcagcagct
361 gtgcgccctt agcaagcacc ccaccgtggc ctttgaagac ctgcagccgt gggtctctaa
421 cttcacctac cctggagccc gggatttctc ccagctggct ttggacccct ccgggaacca
481 gctcatcgtg ggagccagga actacctctt cagactcagc cttgccaatg tctctcttct
541 tcaggccaca gagtgggcct ccagtgagga cacgcgccgc tcctgccaaa gcaaagggaa
601 gactgaggag gagtgtcaga actacgtgcg agtcctgatc gtcgccggcc ggaaggtgtt
661 catgtgtgga accaatgcct tttcccccat gtgcaccagc agacaggtgg ggaacctcag
721 ccggactatt gagaagatca atggtgtggc ccgctgcccc tatgacccac gccacaactc
781 cacagctgtc atctcctccc agggggagct ctatgcagcc acggtcatcg acttctcagg
841 tcgggaccct gccatctacc gcagcctggg cagtgggcca ccgcttcgca ctgcccaata
901 taactccaag tggcttaatg agccaaactt cgtggcagcc tatgatattg ggctgtttgc
961 atacttcttc ctgcgggaga acgcagtgga gcacgactgt ggacgcaccg tgtactctcg
1021 cgtggcccgc gtgtgcaaga atgacgtggg gggccgattc ctgctggagg acacatggac
1081 cacattcatg aaggcccggc tcaactgctc ccgcccgggc gaggtcccct tctactataa
1141 cgagctgcag agtgccttcc acttgccgga gcaggacctc atctatggag ttttcacaac
1201 caacgtaaac agcattgcgg cttctgctgt ctgcgccttc aacctcagtg ctatctccca
1261 ggctttcaat ggcccatttc gctaccagga gaaccccagg gctgcctggc tccccatagc
1321 caaccccatc cccaatttcc agtgtggcac cctgcctgag accggtccca acgagaacct
1381 gacggagcgc agcctgcagg acgcgcagcg cctcttcctg atgagcgagg ccgtgcagcc
1441 ggtgacaccc gagccctgtg tcacccagga cagcgtgcgc ttctcacacc tcgtggtgga
1501 cctggtgcag gctaaagaca cgctctacca tgtactctac attggcaccg agtcgggcac
1561 catcctgaag gcgctgtcca cggcgagccg cagcctccac ggctgctacc tggaggagct
1621 gcacgtgctg ccccccgggc gccgcgagcc cctgcgcagc ctgcgcatcc tgcacagcgc
1681 ccgcgcgctc ttcgtggggc tgagagacgg cgtcctgcgg gtcccactgg agaggtgcgc
1741 cgcctaccgc agccaggggg catgcctggg ggcccgggac ccgtactgtg gctgggacgg
1801 gaagcagcaa cgttgcagca cactcgagga cagctccaac atgagcctct ggacccagaa
1861 catcaccgcc tgtcctgtgc ggaatgtgac acgggatggg ggcttcggcc catggtcacc
1921 atggcaacca tgtgagcact tggatgggga caactcaggc tcttgcctgt gtcgagctcg
1981 atcctgtgat tcccctcgac cccgctgtgg gggccttgac tgcctggggc cagccatcca
2041 catcgccaac tgctccagga atggggcgtg gaccccgtgg tcatcgtggg cgctgtgcag
2101 cacgtcctgt ggcatcggct tccaggtccg ccagcgaagt tgcagcaacc ctgctccccg
2161 ccacgggggc cgcatctgcg tgggcaagag ccgggaggaa cggttctgta atgagaacac
2221 gccttgcccg gtgcccatct tctgggcttc ctggggctcc tggagcaagt gcagcagcaa
2281 ctgtggaggg ggcatgcagt cgcggcgtcg ggcctgcgag aacggcaact cctgcctggg
2341 ctgcggcgtg gagttcaaga cgtgcaaccc cgagggctgc cccgaagtgc ggcgcaacac
2401 cccctggacg ccgtggctgc ccgtgaacgt gacgcagggc ggggcacggc aggagcagcg
2461 gttccgcttc acctgccgcg cgccccttgc agacccgcac ggcctgcagt tcggcaggag
2521 aaggaccgag acgaggacct gtcccgcgga cggctccggc tcctgcgaca ccgacgccct
2581 ggtggaggac ctcctgcgca gcgggagcac ctccccgcac acggtgagcg ggggctgggc
2641 cgcctggggc ccgtggtcgt cctgctcccg ggactgcgag ctgggcttcc gcgtccgcaa
2701 gagaacgtgc actaacccgg agccccgcaa cgggggcctg ccctgcgtgg gcgatgctgc
2761 cgagtaccag gactgcaacc cccaggcttg cccagttcgg ggtgcttggt cctgctggac
2821 ctcatggtct ccatgctcag cttcctgtgg tgggggtcac tatcaacgca cccgttcctg
2881 caccagcccc gcaccctccc caggtgagga catctgtctc gggctgcaca cggaggaggc
2941 actatgtgcc acacaggcct gcccagaagg ctggtcgccc tggtctgagt ggagtaagtg
3001 cactgacgac ggagcccaga gccgaagccg gcactgtgag gagctcctcc cagggtccag
3061 cgcctgtgct ggaaacagca gccagagccg cccctgcccc tacagcgaga ttcccgtcat
3121 cctgccagcc tccagcatgg aggaggccac cggctgtgca gggttcaatc tcatccactt
3181 ggtggccacg ggcatctcct gcttcttggg ctctgggctc ctgaccctag cagtgtacct
3241 gtcttgccag cactgccagc gtcagtccca ggagtccaca ctggtccatc ctgccacccc
3301 caaccatttg cactacaagg gcggaggcac cccgaagaat gaaaagtaca cacccatgga
3361 attcaagacc ctgaacaaga ataacttgat ccctgatgac agagccaact tctacccatt
3421 gcagcagacc aatgtgtaca cgactactta ctacccaagc cccctgaaca aacacagctt
3481 ccggcccgag gcctcacctg gacaacggtg cttccccaac agctgatacc gccgtcctgg
3541 ggacttgggc ttcttgcctt cataaggcac agagcagatg gagatgggac agtggagcca
3601 gtttggtttt ctccctctgc actaggccaa gaacttgctg ccttgcctgt ggggggtccc
3661 atccggcttc agagagctct ggctggcatt gaccatgggg gaaagggctg gtttcaggct
3721 gacatatggc cgcaggtcca gttcagccca ggtctctcat ggttatcttc caacccactg
3781 tcacgctgac actatgctgc catgcctggg ctgtggacct actgggcatt tgaggaattg
3841 gagaatggag atggcaagag ggcaggcttt taagtttggg ttggagacaa cttcctgtgg
3901 cccccacaag ctgagtctgg ccttctccag ctggccccaa aaaaggcctt tgctacatcc
3961 tgattatctc tgaaagtaat caatcaagtg gctccagtag ctctggattt tctgccaggg
4021 ctgggccatt gtggtgctgc cccagtatga catgggacca aggccagcgc aggttattca
4081 cctctgcctg gaagtctata ctctacccag ggcatccctc tggtcagagg cagtgagtac
4141 tgggaactgg aggctgacct gtgcttagaa gtcctttaat ctgggctggt acaggcctca
4201 gccttgccct caatgcacga aaggtggccc aggagagagg atcaatgcca taggaggcag
4261 aagtctggcc tctgtgcctc tatggagact atcttccagt tgctgctcaa cagagttgtt
4321 ggctgagacc tgcttgggag tctctgctgg cccttcatct gttcaggaac acacacacac
4381 acacactcac acacgcacac acaatcacaa tttgctacag caacaaaaaa gacattgggc
4441 tgtggcatta ttaattaaag atgatatcca gtctcaaaaa aaaaaaaaaa aaaa
//