LOCUS BC073990 1396 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens activating transcription factor 4 (tax-responsive
enhancer element B67), mRNA (cDNA clone MGC:88042 IMAGE:6022488),
complete cds.
ACCESSION BC073990
VERSION BC073990.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1396)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1396)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 174 Row: f Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33469973.
FEATURES Location/Qualifiers
source 1..1396
/db_xref="H-InvDB:HIT000265210"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88042 IMAGE:6022488"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_68"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1396
/gene="ATF4"
/gene_synonym="CREB-2"
/gene_synonym="CREB2"
/gene_synonym="TAXREB67"
/db_xref="GeneID:468"
/db_xref="HGNC:HGNC:786"
/db_xref="MIM:604064"
CDS 229..1284
/gene="ATF4"
/gene_synonym="CREB-2"
/gene_synonym="CREB2"
/gene_synonym="TAXREB67"
/codon_start=1
/product="activating transcription factor 4
(tax-responsive enhancer element B67)"
/protein_id="AAH73990.1"
/db_xref="GeneID:468"
/db_xref="HGNC:HGNC:786"
/db_xref="MIM:604064"
/translation="MTEMSFLSSEVLVGDLMSPFDPSGLGAEESLGLLDDYLEVAKHF
KPHGFSSDKAKAGSSEWLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGI
DDLETMPDDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFL
QPLPLSPGVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDND
SGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGE
KLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYL
KDLIEEVRKARGKKRVP"
BASE COUNT 383 a 356 c 372 g 285 t
ORIGIN
1 ctcctccccc gccctcaggg tccacggcca ccatggcgta ttaggggcag cagtgcctgc
61 ggcagcattg gcctttgcag cggcggcagc agcaccaggc tctgcagcgg caacccccag
121 cggcttaagc catggcgctt ctcacggcat tcagcagcag cgttgctgta accgacaaag
181 acaccttcga attaagcaca ttcctcgatt ccagcaaagc accgcaacat gaccgaaatg
241 agcttcctga gcagcgaggt gttggtgggg gacttgatgt cccccttcga cccgtcgggt
301 ttgggggctg aagaaagcct aggtctctta gatgattacc tggaggtggc caagcacttc
361 aaacctcatg ggttctccag cgacaaggct aaggcgggct cctccgaatg gctggctgtg
421 gatgggttgg tcagtccctc caacaacagc aaggaggatg ccttctccgg gacagattgg
481 atgttggaga aaatggattt gaaggagttc gacttggatg ccctgttggg tatagatgac
541 ctggaaacca tgccagatga ccttctgacc acgttggatg acacttgtga tctctttgcc
601 cccctagtcc aggagactaa taagcagccc ccccagacgg tgaacccaat tggccatctc
661 ccagaaagtt taacaaaacc cgaccaggtt gcccccttca ccttcttaca acctcttccc
721 ctttccccag gggtcctgtc ctccactcca gatcattcct ttagtttaga gctgggcagt
781 gaagtggata tcactgaagg agataggaag ccagactaca ctgcttacgt tgccatgatc
841 cctcagtgca taaaggagga agacacccct tcagataatg atagtggcat ctgtatgagc
901 ccagagtcct atctggggtc tcctcagcac agcccctcta ccaggggctc tccaaatagg
961 agcctcccat ctccaggtgt tctctgtggg tctgcccgtc ccaaacctta cgatcctcct
1021 ggagagaaga tggtagcagc aaaagtaaag ggtgagaaac tggataagaa gctgaaaaaa
1081 atggagcaaa acaagacagc agccactagg taccgccaga agaagagggc ggagcaggag
1141 gctcttactg gtgagtgcaa agagctggaa aagaagaacg aggctctaaa agagagggcg
1201 gattccctgg ccaaggagat ccagtacctg aaagatttga tagaagaggt ccgcaaggca
1261 agggggaaga aaagggtccc ctagttgagg atagtcagga gcgtcaatgt gcttgtacat
1321 agagtgctgt agctgtgtgt tccaataaat tattttgtag gaaaaaaaaa aaaaaaaaaa
1381 aaaaaaaaaa aaaaaa
//