LOCUS BC073856 1586 bp mRNA linear HUM 03-NOV-2006
DEFINITION Homo sapiens adrenergic, beta-2-, receptor, surface, mRNA (cDNA
clone MGC:90247 IMAGE:5217922), complete cds.
ACCESSION BC073856
VERSION BC073856.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1586)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1586)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 166 Row: k Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 15718673.
FEATURES Location/Qualifiers
source 1..1586
/db_xref="H-InvDB:HIT000265080"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:90247 IMAGE:5217922"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1586
/gene="ADRB2"
/gene_synonym="ADRBR"
/gene_synonym="B2AR"
/gene_synonym="BAR"
/gene_synonym="BETA2AR"
/db_xref="GeneID:154"
/db_xref="HGNC:HGNC:286"
/db_xref="MIM:109690"
CDS 191..1432
/gene="ADRB2"
/gene_synonym="ADRBR"
/gene_synonym="B2AR"
/gene_synonym="BAR"
/gene_synonym="BETA2AR"
/codon_start=1
/product="adrenergic, beta-2-, receptor, surface"
/protein_id="AAH73856.1"
/db_xref="GeneID:154"
/db_xref="HGNC:HGNC:286"
/db_xref="MIM:109690"
/translation="MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIV
LAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFG
NFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIV
SGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFV
YSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLG
IIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRI
AFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQG
TVPSDNIDSQGRNCSTNDSLL"
BASE COUNT 406 a 432 c 394 g 354 t
ORIGIN
1 ctggaactgg caggcaccgc gagcccctag cacccgacaa gctgagtgtg caggacgagt
61 ccccaccaca cccacaccac agccgctgaa tgaggcttcc aggcgtccgc tcgcggcccg
121 cagagccccg ccgtgggtcc gcccgctgag gcgcccccag ccagtgcgct cacctgccag
181 actgcgcgcc atggggcaac ccgggaacgg cagcgccttc ttgctggcac ccaatggaag
241 ccatgcgccg gaccacgacg tcacgcagga aagggacgag gtgtgggtgg tgggcatggg
301 catcgtcatg tctctcatcg tcctggccat cgtgtttggc aatgtgctgg tcatcacagc
361 cattgccaag ttcgagcgtc tgcagacggt caccaactac ttcatcactt cactggcctg
421 tgctgatctg gtcatgggcc tggcagtggt gccctttggg gccgcccata ttcttatgaa
481 aatgtggact tttggcaact tctggtgcga gttttggact tccattgatg tgctgtgcgt
541 cacggccagc attgagaccc tgtgcgtgat cgcagtggat cgctactttg ccattacttc
601 acctttcaag taccagagcc tgctgaccaa gaataaggcc cgggtgatca ttctgatggt
661 gtggattgtg tcaggcctta cctccttctt gcccattcag atgcactggt accgggccac
721 ccaccaggaa gccatcaact gctatgccaa tgagacctgc tgtgacttct tcacgaacca
781 agcctatgcc attgcctctt ccatcgtgtc cttctacgtt cccctggtga tcatggtctt
841 cgtctactcc agggtctttc aggaggccaa aaggcagctc cagaagattg acaaatctga
901 gggccgcttc catgtccaga accttagcca ggtggagcag gatgggcgga cggggcatgg
961 actccgcaga tcttccaagt tctgcttgaa ggagcacaaa gccctcaaga cgttaggcat
1021 catcatgggc actttcaccc tctgctggct gcccttcttc atcgttaaca ttgtgcatgt
1081 gatccaggat aacctcatcc gtaaggaagt ttacatcctc ctaaattgga taggctatgt
1141 caattctggt ttcaatcccc ttatctactg ccggagccca gatttcagga ttgccttcca
1201 ggagcttctg tgcctgcgca ggtcttcttt gaaggcctat gggaatggct actccagcaa
1261 cggcaacaca ggggagcaga gtggatatca cgtggaacag gagaaagaaa ataaactgct
1321 gtgtgaagac ctcccaggca cggaagactt tgtgggccat caaggtactg tgcctagcga
1381 taacattgat tcacaaggga ggaattgtag tacaaatgac tcactgctgt aaagcagttt
1441 ttctactttt aaagaccccc ccccccaaca gaacactaaa cagactattt aacttgaggg
1501 taataaactt agaataaaat tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1561 aaaaaaaaaa aaaaaaaaaa aaaaaa
//