LOCUS BC073754 1417 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens activating transcription factor 4 (tax-responsive
enhancer element B67), mRNA (cDNA clone MGC:88758 IMAGE:6580199),
complete cds.
ACCESSION BC073754
VERSION BC073754.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1417)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1417)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 58 Row: o Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33469973.
FEATURES Location/Qualifiers
source 1..1417
/db_xref="H-InvDB:HIT000264982"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88758 IMAGE:6580199"
/tissue_type="Ovary, teratocarcinoma"
/clone_lib="NIH_MGC_109"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1417
/gene="ATF4"
/gene_synonym="CREB-2"
/gene_synonym="CREB2"
/gene_synonym="TAXREB67"
/db_xref="GeneID:468"
/db_xref="HGNC:HGNC:786"
/db_xref="MIM:604064"
CDS 254..1309
/gene="ATF4"
/gene_synonym="CREB-2"
/gene_synonym="CREB2"
/gene_synonym="TAXREB67"
/codon_start=1
/product="activating transcription factor 4
(tax-responsive enhancer element B67)"
/protein_id="AAH73754.1"
/db_xref="GeneID:468"
/db_xref="HGNC:HGNC:786"
/db_xref="MIM:604064"
/translation="MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHF
KPHGFSSDKAKAGSSEWLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGI
DDLETMPDDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFL
QPLPLSPGVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDND
SGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGE
KLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYL
KDLIEEVRKARGKKRVP"
BASE COUNT 379 a 361 c 380 g 297 t
ORIGIN
1 gttttctctg cgcgtgtgcg ttttccctcc tccccgccct cagggtccac ggccaccatg
61 gcgtattagg ggcagcagtg cctgcggcag cattggcctt tgcagcggcg gcagcagcac
121 caggctctgc agcggcaacc cccagcggct taagccatgg cgcttctcac ggcattcagc
181 agcagcgttg ctgtaaccga caaagacacc ttcgaattaa gcacattcct cgattccagc
241 aaagcaccgc aacatgaccg aaatgagctt cctgagcagc gaggtgttgg tgggggactt
301 gatgtccccc ttcgaccagt cgggtttggg ggctgaagaa agcctaggtc tcttagatga
361 ttacctggag gtggccaagc acttcaaacc tcatgggttc tccagcgaca aggctaaggc
421 gggctcctcc gaatggctgg ctgtggatgg gttggtcagt ccctccaaca acagcaagga
481 ggatgccttc tccgggacag attggatgtt ggagaaaatg gatttgaagg agttcgactt
541 ggatgccctg ttgggtatag atgacctgga aaccatgcca gatgaccttc tgaccacgtt
601 ggatgacact tgtgatctct ttgcccccct agtccaggag actaataagc agccccccca
661 gacggtgaac ccaattggcc atctcccaga aagtttaaca aaacccgacc aggttgcccc
721 cttcaccttc ttacaacctc ttcccctttc cccaggggtc ctgtcctcca ctccagatca
781 ttcctttagt ttagagctgg gcagtgaagt ggatatcact gaaggagata ggaagccaga
841 ctacactgct tacgttgcca tgatccctca gtgcataaag gaggaagaca ccccttcaga
901 taatgatagt ggcatctgta tgagcccaga gtcctatctg gggtctcctc agcacagccc
961 ctctaccagg ggctctccaa ataggagcct cccatctcca ggtgttctct gtgggtctgc
1021 ccgtcccaaa ccttacgatc ctcctggaga gaagatggta gcagcaaaag taaagggtga
1081 gaaactggat aagaagctga aaaaaatgga gcaaaacaag acagcagcca ctaggtaccg
1141 ccagaagaag agggcggagc aggaggctct tactggtgag tgcaaagagc tggaaaagaa
1201 gaacgaggct ctaaaagaga gggcggattc cctggccaag gagatccagt acctgaaaga
1261 tttgatagaa gaggtccgca aggcaagggg gaagaaaagg gtcccctagt tgaggatagt
1321 caggagcgtc aatgtgcttg tacatagagt gctgtagctg tgtgttccaa taaattattt
1381 tgtagggaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//