LOCUS BC072449 2091 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens X-ray repair complementing defective repair in Chinese
hamster cells 6, mRNA (cDNA clone MGC:87834 IMAGE:6167735),
complete cds.
ACCESSION BC072449
VERSION BC072449.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2091)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2091)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 174 Row: k Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51093847.
FEATURES Location/Qualifiers
source 1..2091
/db_xref="H-InvDB:HIT000264893"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87834 IMAGE:6167735"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2091
/gene="XRCC6"
/gene_synonym="CTC75"
/gene_synonym="CTCBF"
/gene_synonym="KU70"
/gene_synonym="ML8"
/gene_synonym="TLAA"
/db_xref="GeneID:2547"
/db_xref="HGNC:HGNC:4055"
/db_xref="MIM:152690"
CDS 23..1852
/gene="XRCC6"
/gene_synonym="CTC75"
/gene_synonym="CTCBF"
/gene_synonym="KU70"
/gene_synonym="ML8"
/gene_synonym="TLAA"
/codon_start=1
/product="X-ray repair complementing defective repair in
Chinese hamster cells 6"
/protein_id="AAH72449.1"
/db_xref="GeneID:2547"
/db_xref="HGNC:HGNC:4055"
/db_xref="MIM:152690"
/translation="MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDA
SKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNI
YVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFK
MSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYR
DIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNL
VQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEET
EELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEK
EVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTE
KIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTL
PKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKT
HISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD"
BASE COUNT 605 a 454 c 548 g 484 t
ORIGIN
1 gccaaagtga gcagtagcca acatgtcagg gtgggagtca tattacaaaa ccgagggcga
61 tgaagaagca gaggaagaac aagaagagaa ccttgaagca agtggagact ataaatattc
121 aggaagagat agtttgattt ttttggttga tgcctccaag gctatgtttg aatctcagag
181 tgaagatgag ttgacacctt ttgacatgag catccagtgt atccaaagtg tgtacatcag
241 taagatcata agcagtgatc gagatctctt ggctgtggtg ttctatggta ccgagaaaga
301 caaaaattca gtgaatttta aaaatattta cgtcttacag gagctggata atccaggtgc
361 aaaacgaatt ctagagcttg accagtttaa ggggcagcag ggacaaaaac gtttccaaga
421 catgatgggc cacggatctg actactcact cagtgaagtg ctgtgggtct gtgccaacct
481 ctttagtgat gtccaattca agatgagtca taagaggatc atgctgttca ccaatgaaga
541 caacccccat ggcaatgaca gtgccaaagc cagccgggcc aggaccaaag ccggtgatct
601 ccgagataca ggcatcttcc ttgacttgat gcacctgaag aaacctgggg gctttgacat
661 atccttgttc tacagagata tcatcagcat agcagaggat gaggacctca gggttcactt
721 tgaggaatcc agcaagctag aagacctgtt gcggaaggtt cgcgccaagg agaccaggaa
781 gcgagcactc agcaggttaa agctgaagct caacaaagat atagtgatct ctgtgggcat
841 ttataatctg gtccagaagg ctctcaagcc tcctccaata aagctctatc gggaaacaaa
901 tgaaccagtg aaaaccaaga cccggacctt taatacaagt acaggcggtt tgcttctgcc
961 tagcgatacc aagaggtctc agatctatgg gagtcgtcag attatactgg agaaagagga
1021 aacagaagag ctaaaacggt ttgatgatcc aggtttgatg ctcatgggtt tcaagccgtt
1081 ggtactgctg aagaaacacc attacctgag gccctccctg ttcgtgtacc cagaggagtc
1141 gctggtgatt gggagctcaa ccctgttcag tgctctgctc atcaagtgtc tggagaagga
1201 ggttgcagca ttgtgcagat acacaccccg caggaacatc cctccttatt ttgtggcttt
1261 ggtgccacag gaagaagagt tggatgacca gaaaattcag gtgactcctc caggcttcca
1321 gctggtcttt ttaccctttg ctgatgataa aaggaagatg ccctttactg aaaaaatcat
1381 ggcaactcca gagcaggtgg gcaagatgaa ggctatcgtt gagaagcttc gcttcacata
1441 cagaagtgac agctttgaga accccgtgct gcagcagcac ttcaggaacc tggaggcctt
1501 ggccttggat ttgatggagc cggaacaagc agtggacctg acattgccca aggttgaagc
1561 aatgaataaa agactgggct ccttggtgga tgagtttaag gagcttgttt acccaccaga
1621 ttacaatcct gaagggaaag ttaccaagag aaaacacgat aatgaaggtt ctggaagcaa
1681 aaggcccaag gtggagtatt cagaagagga gctgaagacc cacatcagca agggtacgct
1741 gggcaagttc actgtgccca tgctgaaaga ggcctgccgg gcttacgggc tgaagagtgg
1801 tctgaagaag caggagctgc tggaagccct caccaagcac ttccaggact gaccagaggc
1861 cgcgcgtcca gctgcccttc cgcagtgtgg ccaggctgcc tggccttgtc ctcagccagt
1921 taaaatgtgt ttctcctgag ctaggaagag tctacccgac ataagtcgag ggactttatg
1981 tttttgaggc tttctgttgc catggtgatg gtgtagccct cccactttgc tgttccttac
2041 tttactgcct gaataaagag ccctaagttt gtactaaaaa aaaaaaaaaa a
//